hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mtj/mtj00724/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1739  ( 755 res)   mtj00724

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
Sema     Sema domain                                    624.4   6.6e-184   1
PSI      Plexin repeat                                   35.3    1.4e-06   1
ig       Immunoglobulin domain                           17.2       0.38   1
V-set    Immunoglobulin V-set domain                      6.3       0.14   1
I-set    Immunoglobulin I-set domain                     -7.5      0.049   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Sema       1/1       1   402 [.     1   490 []   624.4 6.6e-184
PSI        1/1     420   473 ..     1    63 []    35.3  1.4e-06
ig         1/1     492   551 ..     1    65 []    17.2     0.38
I-set      1/1     478   561 ..     1    97 []    -7.5    0.049
V-set      1/1     477   561 ..     1   130 []     6.3     0.14

Alignments of top-scoring domains:
Sema: domain 1 of 1, from 1 to 402: score 624.4, E = 6.6e-184
                   *->frtllldedrgrLyVGArNhvyvLnledlserlqqkigWpsspgeek
                       r+    e+               +l +l++r              +
   mKIAA1739     1    -RLWSCKER---------------SLGRLQLR---------R--KLN 20   

                   ceeCkmkgkspgcVeteCqNfirVLqpyndthLyvCGTnaFqPvCtlinl
                         kg      +teC+Nfir Lqpyn++hLyvCGT+aFqP+Ct+in+
   mKIAA1739    21 ---VPRKGRA----QTECFNFIRFLQPYNSSHLYVCGTYAFQPKCTYINM 63   

                   gdrseaviiaetdcLFsldvekeesGkgrCPydPlhnstsvlvqgrtgeL
                    +             F+ld +++e+Gkg+CPydP++++t++lv +  geL
   mKIAA1739    64 LT-------------FTLDRAEFEDGKGKCPYDPAKGHTGLLV-D--GEL 97   

                   YsGtviDssvaasFsGrdpaIrRslgshdplrTeqhdskwlnePnFVdsy
                   Ys+t+++      F+G++p+I R++g+h+ ++Te+  + wlneP+FV+s 
   mKIAA1739    98 YSATLNN------FLGTEPVILRYMGTHHSIKTEY-LAFWLNEPHFVGSA 140  

                   pipyvhsf...dDdkVYFFFrEtaveyspnsgkaiysRVaRvCknDvGGr
                    +p++    ++dDdk+YFFF E+avey+ ++++++++RVaRvCk+D+GG+
   mKIAA1739   141 FVPESVGSftgDDDKIYFFFSERAVEYD-CYSEQVVARVARVCKGDMGGA 189  

                   rylelnkWTTFLKARLnCSvpGeegipkfyFNeLQavfllptganlAreL
                   r+l+ +kWTTFLKARL+CS p+  +  k+yFN+L+av++l+ +++     
   mKIAA1739   190 RTLQ-KKWTTFLKARLVCSAPD--W--KVYFNQLKAVHTLRGASW----- 229  

                   gIserdpviYGVFttssnsiagpgdnSAVCaFsmsdIrqvFenGpfkhqs
                       +++ ++GVF+  + ++      SAVC +++ +I+qvF +Gp+k++s
   mKIAA1739   230 ----HNTTFFGVFQARWGDMDL----SAVCEYQLEQIQQVF-EGPYKEYS 270  

                   nEgpnskwlpyrglkvPyPRPGqCpndssgp.nytStkdlPDdtlnfiks
                    E+++ kw +y++ +vP+PRPG+C+n+++++++ytS+++lPD+tlnfik+
   mKIAA1739   271 -EQAQ-KWARYTD-PVPSPRPGSCINNWHRDnGYTSSLELPDNTLNFIKK 317  

                   hpLmdevvpPlhnrPlfvgtsvnyrlTqIaVdkrVragdGqlYtVlFlGT
                   hpLm+++v+P  +rPl+v++++  ++T++++d rV+++dG +YtVlF+GT
   mKIAA1739   318 HPLMEDQVKPRLGRPLLVKKNT--NFTHVVAD-RVPGLDGATYTVLFIGT 364  

                   ddGtvlKkvvvlsrsss.syeevvleelqvfkdpriePvqnleisskq<-
                    dG++l k+v+l  + + +    ++eelqvf d+  ePv++l++s+++  
   mKIAA1739   365 GDGWLL-KAVSL--GPWiH----MVEELQVF-DQ--EPVESLVLSQSK   402  

                   *
                    
   mKIAA1739     -   -    

PSI: domain 1 of 1, from 420 to 473: score 35.3, E = 1.4e-06
                   *->nCsqytsCssCLaardpfyCgWCssegrCtrgsayts.....f.yGe
                      +C  y+ C +C++ardp yC+W ++++rC+  +   s+++++f +++
   mKIAA1739   420    DCTKYRFCVDCVLARDP-YCAWNVNTSRCVATT---SgrsgsFlVQH 462  

                   CpraependqwldwswssskCp<-*
                     + +           +s+ C    
   mKIAA1739   463 VANLD-----------TSKMCN    473  

ig: domain 1 of 1, from 492 to 551: score 17.2, E = 0.38
                   *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyq
                      G ++ L+C+    ++  ++ +W++++++l+ ++++ +  + g +   
   mKIAA1739   492    GTDLVLPCHL---SSNLAHAHWTFGSQdLPaEQPGSFLYDTGLQA-- 533  

                   tsLtitnvtpeDggtYtCvv<-*
                     L++ ++++ ++g Y+C+    
   mKIAA1739   534 --LVVMAAQSRHSGPYRCYS    551  

I-set: domain 1 of 1, from 478 to 561: score -7.5, E = 0.049
                   *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVsWfKdGqplssvllp
                       k   +pk+++V  G ++++ C+ + +      W+ + q+l++    
   mKIAA1739   478    KKVRSIPKNITVVSGTDLVLPCHLSSN-LAHAHWTFGSQDLPA---- 519  

                   sdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeaeasaeLtVq
                   ++  ++ yd   g + L++  +q++ sG Y+C+      + e   +L  +
   mKIAA1739   520 EQPGSFLYDT--GLQALVVMAAQSRHSGPYRCY------SEEQGTRLAAE 561  

                   <-*
                      
   mKIAA1739     -     -    

V-set: domain 1 of 1, from 477 to 561: score 6.3, E = 0.14
                   *->qstvtqepprLLLASLfWptsvtvaeGgsvtLpCtysGtfddsssss
                         v    p+           +tv+ G+++ LpC++s     s    
   mKIAA1739   477    IKKVRS-IPK----------NITVVSGTDLVLPCHLS-----S---- 503  

                   gtgsvyWyrq.qppGekpeliiisyytyysysegngtvserfkgrvrfsg
                   +  + +W +++q++                        + + +g++ ++ 
   mKIAA1739   504 NLAHAHWTFGsQDL------------------------PAEQPGSF-LYD 528  

                   npskgdfsLtIsnlqlsDsGtYyCa..gggtrLtVl<-*
                   ++      L  + +q+ +sG Y C ++++gtrL  +   
   mKIAA1739   529 TGL---QALVVMAAQSRHSGPYRCYseEQGTRLAAE    561  

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