hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbh/mbh01547/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1727  ( 1159 res)   mbh01547

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
FH2      Formin Homology 2 Domain                       417.3   1.4e-121   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
FH2        1/1      99   468 ..     1   413 []   417.3 1.4e-121

Alignments of top-scoring domains:
FH2: domain 1 of 1, from 99 to 468: score 417.3, E = 1.4e-121
                   *->kkepkpkkkLKpLhWdKlnpsqdrgt.svWdkldeesfekkldldls
                       ++  +kk++++++W+ ++++q+rg++++W+   ++++++  ++d +
   mKIAA1727    99    YSSLGKKKRMRSFFWKTIPEEQVRGKtNIWTLAAKQQHQY--QIDKK 143  

                   elEelFsakakkkkekks...seksskskkkkkeisvLDpkrsQNiaIlL
                    +EelF+ ++ ++k++ ++++   +s+ + +++e++vLD+krs+Ni+I+L
   mKIAA1727   144 TIEELFGQQEDTSKASLPkrgGALNSSFRDAREEVTVLDAKRSMNIGIFL 193  

                   rklsklppeeivqAilemDedvLgvvlflkemldllenLlkmaPtkeElk
                   +++ k++p+ iv+ i ++ +++ g         ++l   lk +P++eE+k
   mKIAA1727   194 KQF-KKSPQSIVEDIYQGKSEHYG--------SETLREILKLLPESEEVK 234  

                   klqekeykgdekspskLgraEqqFLlelskliprleeRlrallFkstFee
                   kl  k+++gd   +skL+ a+ +FL  l++ +p++++R++a+  k++F +
   mKIAA1727   235 KL--KAFNGD---VSKLSLAD-SFLHCLIQ-VPNYSLRIEAMVLKKEFLP 277  

                   eveelkpsletleaAseeLreSrkfkklLeliLalGNyMNsGtrrrGnAk
                   ++  l ++++tl+aA++eL+ ++ ++++L+l+L++GN+MN+G +  GnA+
   mKIAA1727   278 SCSSLFKDIRTLRAATKELMLCEELHSILHLVLQAGNIMNAGGYA-GNAV 326  

                   GFkLssLlKLsdvKstidnktTLLHflvkeieesEGkrlEeyrKLklpel
                   GFkLssLlKL+d+K++ +  ++LLHf+++e  +                l
   mKIAA1727   327 GFKLSSLLKLADTKAN-KPGMNLLHFVAQEAQK------------QDAIL 363  

                   ldfsseLshVekAakvdleeLeadvkeLekglkklekelelseeSkvsde
                   l+fs+ L+hV+++++++l+  ea++++L  + k l+++++l  e      
   mKIAA1727   364 LNFSEKLQHVQETSRLSLDITEAELHSLFVRTKSLQENIQLDQE------ 407  

                   epsdkFvevmkeFleeAeekldkLesllkeakelfkelteYFghggedpk
                        ++++m++Fl+ A ekl++Le + +e++ + + l+++F   +ed++
   mKIAA1727   408 -----LCQQMEDFLQFAVEKLAELELWKRELQGEAHTLIDFF---CEDKE 449  

                   detspeeFFkilrdFlnefk<-*
                    ++ ++e+F+i+rdF++ f+   
   mKIAA1727   450 -TMKLDECFQIFRDFCTRFN    468  

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