hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg15369/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1722  ( 1337 res)   mbg15369

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RhoGAP   GTPase-activator protein for Rho-like GTPase   253.8    1.4e-71   1
FF       Contains two conserved F residues              149.8    2.8e-40   4

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
FF         1/4     108   165 ..     1    64 []    45.0  9.8e-09
FF         2/4     207   260 ..     1    64 []    34.1  1.9e-05
FF         3/4     267   321 ..     1    64 []    54.6  1.3e-11
FF         4/4     323   377 ..     1    64 []    29.9  0.00034
RhoGAP     1/1    1097  1271 ..     1   193 []   253.8  1.4e-71

Alignments of top-scoring domains:
FF: domain 1 of 4, from 108 to 165: score 45.0, E = 9.8e-09
                   *->reeakeaFkelLkehevitkksKiEpdttWseakkkikdDpryke.i
                      + +ak+++ +l ++++++       ++ +W  +++k++ +p+y + +
   mKIAA1722   108    IATAKDKYEWLVSRIVKN-------HNENWPSVSRKMQASPEYQDyV 147  

                   allsesereqlFedyiee<-*
                   +l+++ ++++lF ++i++   
   mKIAA1722   148 YLEGTQKAKKLFLQHIHR    165  

FF: domain 2 of 4, from 207 to 260: score 34.1, E = 1.9e-05
                   *->reeakeaFkelLkehevitkksKiEpdttWseakkkikdDprykeia
                      + e k +F +++  +e+          t+W+ +++++ ++ + ++++
   mKIAA1722   207    LLETKPEFLKWFVVLEE----------TPWDATSHIDNMENERIPFD 243  

                   llsesereqlFedyiee<-*
                   l+++ ++eql+e + e+   
   mKIAA1722   244 LMDTVPAEQLYETHLEK    260  

FF: domain 3 of 4, from 267 to 321: score 54.6, E = 1.3e-11
                   *->reeakeaFkelLkehevitkksKiEpdttWseakkkikdDprykeia
                      r e+++aFke L++ ++it      p+ +W+ea+++i++++ y   +
   mKIAA1722   267    RAEMRRAFKENLETSPFIT------PGKPWEEARSFIMNEDFY---Q 304  

                   llsesereqlFedyiee<-*
                   +l+es   +++ +++++   
   mKIAA1722   305 WLEESVYMDIYGKHQKQ    321  

FF: domain 4 of 4, from 323 to 377: score 29.9, E = 0.00034
                   *->reeakeaFkelLkehevitkksKiEpdttWseakkkikdDprykeia
                      +++ake+F+elL e+++ +      ++   +   +k k+  +    +
   mKIAA1722   323    IDRAKEEFQELLLEYSELF------YELELDAKPSKEKMGVIQ---D 360  

                   llsesereqlFedyiee<-*
                   +l+e+ r ++ ++ ++e   
   mKIAA1722   361 VLGEEQRFKALQKLQAE    377  

RhoGAP: domain 1 of 1, from 1097 to 1271: score 253.8, E = 1.4e-71
                   *->spiPiivekCieylekrGldteGIYRvsGsksrvkeLreafdsged.
                      +piPi++e+Ciey+e+ Gl teGIYRvsG+ks+++ L+++fd+++  
   mKIAA1722  1097    KPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNl 1143 

                   dldsldesiteesedleeydvhdvAglLKlyLReLPePLltfelyeefie
                   d            +++ +++v++vAg+ K+++ eLP+PL++++++ +++e
   mKIAA1722  1144 D------------LAEKDFTVNTVAGAMKSFFSELPDPLVPYSMQIDLVE 1181 

                   aaklyqieatsrkqseksedeeerlralrellslLPpanratLryLl.HL
                   a k+              +d+e++l+al+e+l+++P++n+++++y+++HL
   mKIAA1722  1182 AHKI--------------NDREQKLHALKEVLKKFPKENHEVFKYVIsHL 1217 

                   nrVaehsevNkMtarNLAivFgPtLlrpp......ltdikhqnkvvetli
                   n+V+ + +vN+Mt++NL+i+F PtL+rp+ ++ + lt+++  ++++e +i
   mKIAA1722  1218 NKVSHNNKVNLMTSENLSICFWPTLMRPDfssmdaLTATRSYQTIIELFI 1267 

                   enad<-*
                   ++++   
   mKIAA1722  1268 QQCP    1271 

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