hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg15369/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1722  ( 1337 res)   mbg15369

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RhoGAP   RhoGAP domain                                  242.3    6.8e-69   1
FF       FF domain                                       50.9    2.9e-11   2
Ras      Ras family                                     -88.8      0.083   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Ras        1/1       1    87 [.     1   174 []   -88.8    0.083
FF         1/2     110   162 ..     1    64 []    17.1     0.23
FF         2/2     325   385 ..     1    64 []    37.2  3.9e-07
RhoGAP     1/1    1100  1251 ..     1   155 []   242.3  6.8e-69

Alignments of top-scoring domains:
Ras: domain 1 of 1, from 1 to 87: score -88.8, E = 0.083
                   *->KlVlvGDgGVGKSsLliRFtdnkFpeeYipTIGvDFytktvevdgkt
                                                      G+D  +      + +
   mKIAA1722     1    --------------------------------GIDVSRGMNRNFDDQ 15   

                   vkLqIWDTAGQErFralrpaYYRgAqGfLLVYDITsrdSFenvkkWleei
                    k+                                       v + + ++
   mKIAA1722    16 LKF---------------------------------------VSNLYNQL 26   

                   lrhadkdenvpivLVGNKcDLeddedlelekqkRqVsteeGealAkelgA
                    + +   + +++vL  +KcD            +R +   ++  +A ++++
   mKIAA1722    27 AKTKK--P-IVVVL--TKCDEGV---------ERYIR--DAHTFALSKKN 60   

                   lpFmETSAKtneNVeeaFeelareilk<-*
                   l+ +ETSA++n+NV+ aF +l++ i k   
   mKIAA1722    61 LQVVETSARSNVNVDLAFSTLVQLIDK    87   

FF: domain 1 of 2, from 110 to 162: score 17.1, E = 0.23
                   *->kakeaFreLLkehkvityakklliktsnstWseakkkls...eDpry
                      +ak+ +++L +   +++             W  +++k + ++e+  y
   mKIAA1722   110    TAKDKYEWLVSRIVKNHN----------ENWPSVSRKMQaspEYQDY 146  

                   ialdsesylksereqlFedy<-*
                   ++l+++     ++++lF ++   
   mKIAA1722   147 VYLEGTQ----KAKKLFLQH    162  

FF: domain 2 of 2, from 325 to 385: score 37.2, E = 3.9e-07
                   *->kakeaFreLLkehkvityak.klliktsnstWseakkklseDpryia
                      +ake+F+eLL e +   y +  l +k+s  ++  ++++l e+ r++a
   mKIAA1722   325    RAKEEFQELLLEYSELFY-ElELDAKPSKEKMGVIQDVLGEEQRFKA 370  

                   ldsesylksereqlFedy<-*
                   l+++     er  l+ ++   
   mKIAA1722   371 LQKLQ---AERDALILKH    385  

RhoGAP: domain 1 of 1, from 1100 to 1251: score 242.3, E = 6.8e-69
                   *->PlivekCieflekrGLdtEGIyRvsGsksrikeLreafdrgedvdln
                      P+++e+Cie++e+ GL tEGIyRvsG+ks+++ L+ +fd+++  dl 
   mKIAA1722  1100    PIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDL- 1145 

                   dleeedvhvvAslLKlFLReLPePLltfelyeefieaaaksedeeerlea
                    +++++v++vA++ K F+ eLP+PL+++++  +++e a k++d+e++l+a
   mKIAA1722  1146 AEKDFTVNTVAGAMKSFFSELPDPLVPYSMQIDLVE-AHKINDREQKLHA 1194 

                   lrellrkLPpaNrdtLryLlahLnrVaqnsevNkMtahNLAivFgPtLlr
                   l+e+l+k+P++N+++++y + hLn+V+ n +vN+Mt++NL+i+F+PtL+r
   mKIAA1722  1195 LKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMR 1244 

                   ppdgdsad<-*
                   p+ + s+d   
   mKIAA1722  1245 PDFS-SMD    1251 

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