hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg16135/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1708  ( 1291 res)   mbg16135

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
WD40     WD domain, G-beta repeat                       183.6    3.2e-51   7
Ebp2     Eukaryotic rRNA processing protein EBP2       -142.5       0.76   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Ebp2       1/1     236   503 ..     1   345 []  -142.5     0.76
WD40       1/7     955   990 ..     1    38 []    41.1  2.5e-08
WD40       2/7     995  1031 ..     1    38 []    15.7      1.1
WD40       3/7    1059  1095 ..     1    38 []    17.3     0.37
WD40       4/7    1100  1140 ..     1    38 []    30.0  5.3e-05
WD40       5/7    1150  1186 ..     1    38 []    20.4    0.042
WD40       6/7    1192  1229 ..     1    38 []    27.5   0.0003
WD40       7/7    1234  1269 ..     1    38 []    35.9    9e-07

Alignments of top-scoring domains:
Ebp2: domain 1 of 1, from 236 to 503: score -142.5, E = 0.76
                   *->esdieasDleelededdesDrEl.qsafdsGllkeglnvllegkKka
                      e+d+e++D  e+e ++desD+E+++ a+ + +l  ++   + ++K++
   mKIAA1708   236    EEDEEEEDDIEGEESSDESDSESdEKANYQADLANITCEIAIKQKLI 282  

                   iNdvqgLkqkleeikykeDlpWvErLdVettlgpmkhaLervllpekkks
                       ++L+++ +++  +    + E+L +   + +    Ler +     +s
   mKIAA1708   283 ----DELENSQKRL-QTLKKQYEEKLMM-LQHKIRDTQLERDQVLQNLGS 326  

                   aqehqsnasetnidpeikdvnDDfqRElaFYkQAqsAVlaAfprLreLgV
                     e  s+ + + +  e              Y   + A    + rL  +  
   mKIAA1708   327 V-ESYSEEKAKKVKCE--------------YEKKLHAMNKELQRLQTA-- 359  

                   ktkRPtDYFAEMaKSDeHMqKVRqkLlkeqaakeksEeakki..RelKKf
                                      qK  ++Llk q++ ek+ +  +++  e KK 
   mKIAA1708   360 -------------------QKEHARLLKNQSQYEKQLKKLQQdvMEMKK- 389  

                   GKkVQkevlqkRqkEKkemle........kiKKlkKgrkqnliDflelek
                     kV + ++ k ++EK+ + e++++++  ++KK +++r ++l   le   
   mKIAA1708   390 -TKVRLMKQMKEEQEKARLTEsrrnreiaQLKKDQRKRDHQL-RLLE--- 434  

                   edDfdsaksaqrGagGdrlgvasgdgvggegrgqrmrkqkpnaaKRkkK.
                                          + ++  e+   r +     a+ R+ ++
   mKIAA1708   435 -----------------------AQKRNQEVVLRRKTEE-VTALRRQVRp 460  

                   .nqKFGfGGkKkgsKrNtkeSsaDvsGfrsglahGkGrrrpGkKgGassn
                    ++K    Gk  ++ +   +   D+ +  ++              G   +
   mKIAA1708   461 mSDK--VAGKVTRKLSSSESPAPDTGSSAAS--------------GEADT 494  

                   kRpGKarReKr<-*
                    RpG  + +K+   
   mKIAA1708   495 SRPG--TQQKM    503  

WD40: domain 1 of 7, from 955 to 990: score 41.1, E = 2.5e-08
                   *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-*
                      +c+++ +gHt++V cv+   d   ll++gS D+t+k+W+   
   mKIAA1708   955    QCVHIAeGHTKAVLCVDSTDD---LLFTGSKDRTCKVWN    990  

WD40: domain 2 of 7, from 995 to 1031: score 15.7, E = 1.1
                   *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-*
                      + + +l+ H + V +v+++    +l+++ S    ik+Wd   
   mKIAA1708   995    QEIMSLgVHPNNVVSVKYCNY-TSLVFTVST-SYIKVWD    1031 

WD40: domain 3 of 7, from 1059 to 1095: score 17.3, E = 0.37
                   *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-*
                        +  ++  +s ++ +a +p  g++l  +S  + +++Wd   
   mKIAA1708  1059    SRTVAIpSGESQINQIALNPT-GTFLYAASG-NAVRMWD    1095 

WD40: domain 4 of 7, from 1100 to 1140: score 30.0, E = 5.3e-05
                   *->eclavl.gHtspVtcvafspd..sgpllasgSrDgtikiWd<-*
                      + +  l+gH +pV+c+ +++ ++++ l+++gS D+ ik++d   
   mKIAA1708  1100    QSTGKLtGHLGPVMCLTVDQIsnGQDLIITGSKDHYIKMFD    1140 

WD40: domain 5 of 7, from 1150 to 1186: score 20.4, E = 0.042
                   *->eclavl..gHtspVtcvafspdsgpllasgSrDgtikiWd<-*
                       +++ +++ H ++++++a+  d    l+sgSrD+ ik Wd   
   mKIAA1708  1150    SPTHNFepPHYDGIEALAIQGD---NLFSGSRDNGIKKWD    1186 

WD40: domain 6 of 7, from 1192 to 1229: score 27.5, E = 0.0003
                   *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-*
                       +++v ++H+++V+++  +p   p+l+sg+r g +k+W+   
   mKIAA1708  1192    LLQQVPnAHKDWVCALGLVPG-HPVLLSGCRGGILKLWN    1229 

WD40: domain 7 of 7, from 1234 to 1269: score 35.9, E = 9e-07
                   *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-*
                       ++ + +gH sp+++++++     +++++ +D+t++iW+   
   mKIAA1708  1234    VPVGEMrGHDSPINAICVNST---HVFTAADDRTVRIWK    1269 

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