hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/smart.HMMs Sequence file: /cdna4/rodent/full/goal/meh/meh02165/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA1679 ( 1608 res) meh02165 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- TSP1 Thrombospondin type 1 repeats 254.3 1e-71 17 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- TSP1 1/17 44 99 .. 1 66 [] -1.1 15 TSP1 2/17 183 234 .. 1 66 [] 45.9 5.5e-09 TSP1 3/17 340 400 .. 1 66 [] 44.2 1.7e-08 TSP1 4/17 488 544 .. 1 66 [] 13.4 0.35 TSP1 5/17 605 662 .. 1 66 [] 38.6 8.3e-07 TSP1 6/17 665 736 .. 1 66 [] 21.4 0.044 TSP1 7/17 741 797 .. 1 66 [] 33.8 2.3e-05 TSP1 8/17 800 870 .. 1 66 [] -3.5 27 TSP1 9/17 875 923 .. 1 66 [] 24.0 0.021 TSP1 10/17 953 1000 .. 1 66 [] 4.1 3.8 TSP1 11/17 1005 1060 .. 1 66 [] 41.9 8.7e-08 TSP1 12/17 1063 1127 .. 1 66 [] 5.4 2.8 TSP1 13/17 1132 1183 .. 1 66 [] 28.0 0.0013 TSP1 14/17 1186 1247 .. 1 66 [] 7.7 1.5 TSP1 15/17 1252 1304 .. 1 66 [] 42.1 7.3e-08 TSP1 16/17 1305 1370 .. 1 66 [] 9.8 0.88 TSP1 17/17 1375 1433 .. 1 66 [] 20.0 0.063 Alignments of top-scoring domains: TSP1: domain 1 of 17, from 44 to 99: score -1.1, E = 15 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg + +++W+ C g CG G g ++R +c ++ + mKIAA1679 44 LWKTGPWGRCAG-DCGPG----GAQSRAV----WCFHIEGWT--SPM 79 epCs......EtrpCntqpnLqpCp<-* ++C+++++++ r C+ +C+ mKIAA1679 80 SNCDessqppKERSCFR-----VCD 99 TSP1: domain 2 of 17, from 183 to 234: score 45.9, E = 5.5e-09 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg +se+s+WS+C + CG ++ ++RtR v + pp gg mKIAA1679 183 VSEFSPWSTCP-EGCG-----KKLQHRTR----VAIAPPL----YGG 215 epCs...EtrpCntqpnLqpCp<-* +C++ +E+r+C+ + Cp mKIAA1679 216 LQCPnltESRACEAPV---SCP 234 TSP1: domain 3 of 17, from 340 to 400: score 44.2, E = 1.7e-08 *->wseWseWSpCSgvtCGgGgrte...gvrtRtRsslrvccspppprnq seWs+WSpCS +tC +G + ++gvr+R+R + + + mKIAA1679 340 TSEWSPWSPCS-KTCRSG---TlspGVRSRSR-----NVKHIA---I 374 nggepCs...EtrpCntqpn.LqpCp<-* gg++C++ E+++C + LqpCp mKIAA1679 375 GGGQECPellEKETCIAEGEfLQPCP 400 TSP1: domain 4 of 17, from 488 to 544: score 13.4, E = 0.35 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg +s+Ws W+pC + C + +g+r+R+R+ + + +p mKIAA1679 488 VSSWSTWGPCVFENCHDPQGKKGFRMRQRH-VLMESTGPM------- 526 epCs...EtrpCntqpnLqpCp<-* ++C++ E+ pC+ + C+ mKIAA1679 527 GRCPhlaESVPCEDP----MCH 544 TSP1: domain 5 of 17, from 605 to 662: score 38.6, E = 8.3e-07 *->wseWseWSpCSgvtCG....gGgrtegvrtRtRsslrvccspppprn +seW+ WS+CS ++C ++++ G +tR+R +++ ++ mKIAA1679 605 VSEWTVWSSCS-QSCSnknsDG-----KQTRSR-----SILALAG-- 638 qnggepCs......EtrpCntqpnLqpCp<-* gg+ C+++++ +E+r Cn + C mKIAA1679 639 -EGGKTCPssqelqEYRLCNDH----SCT 662 TSP1: domain 6 of 17, from 665 to 736: score 21.4, E = 0.044 *->wseWseWSpCSg................vtCGgGgrtegvrtRtRss +e+s W++CS ++ + + + + ++++tCG G ++tR+ mKIAA1679 665 YWETSAWGSCSEntlvtalnvtigwngeATCGVG-----IQTRKV-- 704 lrvccspppprnqnggepCs......EtrpCntqpnLqpCp<-* +c+ + + q+ ++C+++++++ +rpC++ pC mKIAA1679 705 --FCIKSHVG--QVMTKRCPestrpeTVRPCFL-----PCK 736 TSP1: domain 7 of 17, from 741 to 797: score 33.8, E = 2.3e-05 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg ++++seW+pC ++C G t+ ++R+R + ++ ngg mKIAA1679 741 VTAFSEWTPCP-RPCQPG-NTTIKQSRYRI----IIQEAA----NGG 777 epCs....EtrpCntqpnLqpCp<-* ++C+++ E r+C+ Cp mKIAA1679 778 QECPdtlfEERECEDIS---LCP 797 TSP1: domain 8 of 17, from 800 to 870: score -3.5, E = 27 *->wseWseWSpC..............SgvtCGgGgrtegvrtRtRsslr + WS+C +++ +++++++S + CG+G +tR s mKIAA1679 800 RWKPQKWSSCilvpesirqgrtgtS-EACGKG-----LQTRAVS--- 837 vccspppprnqnggepCs........EtrpCntqpnLqpCp<-* c+s ++ +C ++ ++ ++ +++C+ pC mKIAA1679 838 -CISDDNQ--SAEMTECLkqmngmppLVQECTI-----PCR 870 TSP1: domain 9 of 17, from 875 to 923: score 24.0, E = 0.021 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg ++Ws +pCS + C e +++R+R + +++ mKIAA1679 875 FTPWSKFTPCS-KNC------EATQIRRR-----QLTGKSRKK---- 905 epCs...EtrpCntqpnLqpCp<-* e C++ + + +++ pCp mKIAA1679 906 EKCQdasLYPLVEME----PCP 923 TSP1: domain 10 of 17, from 953 to 1000: score 4.1, E = 3.8 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg w + + + CG+G vr R cs+ ++r+ ++ mKIAA1679 953 WVQGD-----D-KECGEG-----VRFRAI-----ACSNINGRP-VDP 982 epCs....EtrpCntqpnLqpCp<-* + C +++ +++C pCp mKIAA1679 983 SFCNssgyIQEACVI-----PCP 1000 [output cut off at A = 10 top alignments] //