hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file: /cdna4/rodent/full/goal/mbg/mbg08078/w3open/interpro/cnk_1/seq.in
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Query: mKIAA1621 ( 810 res) mbg08078
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
CA Cadherin repeats. 394.2 7.5e-114 5
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CA 1/5 166 251 .. 1 121 [] 75.8 5.4e-18
CA 2/5 275 356 .. 1 121 [] 94.1 1.7e-23
CA 3/5 379 460 .. 1 121 [] 84.5 1.3e-20
CA 4/5 484 570 .. 1 121 [] 97.3 1.8e-24
CA 5/5 600 681 .. 1 121 [] 57.9 1.3e-12
Alignments of top-scoring domains:
CA: domain 1 of 5, from 166 to 251: score 75.8, E = 5.4e-18
*->vsAtDaDsgsngeNgkpgdaevvtYsils.....lFsIdpetGtngp
+A D D N tY+++s+++ + +++ G ++p
mKIAA1621 166 NNALDSDVA---INNI------QTYRLSSnshflVVTRNRSDGRKYP 203
sLvkleiiitttkpLDREeqflkreqtdeseYtLtveAtDgGgpppgdss
++++ k+LDREe +e +Lt +A DgG pp
mKIAA1621 204 -------ELVLEKELDREEE---------PELRLTLTALDGGAPP----- 232
ptrksqqtpplsstatvtvtVlDvNDNaP<-*
+s+ta+v ++V+D+NDNaP
mKIAA1621 233 ----------RSGTAQVLIEVVDINDNAP 251
CA: domain 2 of 5, from 275 to 356: score 94.1, E = 1.7e-23
*->vsAtDaDsgsngeNgkpgdaevvtYsils.......lFsIdpetGtn
vsA D+Dsg + gk v Y +++++++ ++ +++p tG
mKIAA1621 275 VSANDLDSG---DYGK------VLYALSQpsediskTLEVNPVTG-- 310
gpsLvkleiiitttkpLDREeqflkreqtdeseYtLtveAtDgGgpppgd
+i+++k+ D+E++ ++Y++ ++AtDgGg
mKIAA1621 311 ---------EIRLRKEVDFETI---------PSYEVDIKATDGGG----- 337
ssptrksqqtpplsstatvtvtVlDvNDNaP<-*
ls+ +t+ +V+DvNDNaP
mKIAA1621 338 ------------LSGKCTLLLKVVDVNDNAP 356
CA: domain 3 of 5, from 379 to 460: score 84.5, E = 1.3e-20
*->vsAtDaDsgsngeNgkpgdaevvtYsils..lFsIdpetGtngpsLv
+s+ D+Ds +Ngk si+++ +F + +++ +
mKIAA1621 379 FSVKDPDSA---NNGK------MIASIEEdlPFLLKSSGKN------ 410
kleiiitttkpLDREeqflkreqtdeseYtLtveAtDgGgpppgdssptr
+++++t+++LDREe+ ++Y++t++++D G+p+
mKIAA1621 411 --FYTLVTKRALDREER---------EKYNITITVSDLGTPR-------- 441
ksqqtpplsstatvtvtVlDvNDNaP<-*
l+++ t+tv+V D NDNaP
mKIAA1621 442 -------LTTQHTITVQVSDTNDNAP 460
CA: domain 4 of 5, from 484 to 570: score 97.3, E = 1.8e-24
*->vsAtDaDsgsngeNgkpgdaevvtYsils..........lFsIdpet
+sAtD D+g +N++ ++Ys+l++++++ ++l sI++++
mKIAA1621 484 ISATDSDAG---SNSH------ISYSLLPshdpqlaldsLISINADN 521
GtngpsLvkleiiitttkpLDREeqflkreqtdeseYtLtveAtDgGgpp
G +++++++LD+E+ + +++ v A D+G+p
mKIAA1621 522 G-----------QLFALRALDYEAL---------QAFEFHVGAIDQGSPA 551
pgdssptrksqqtpplsstatvtvtVlDvNDNaP<-*
lss+a v+v VlD NDNaP
mKIAA1621 552 ---------------LSSQALVRVVVLDDNDNAP 570
CA: domain 5 of 5, from 600 to 681: score 57.9, E = 1.3e-12
*->vsAtDaDsgsngeNgkpgdaevvtYsils.....lFsIdpetGtngp
v+A+D+Dsg +N++ +++++l ++++lFs+ +++G
mKIAA1621 600 VVAVDRDSG---QNAW------LSFQLLKatepgLFSVWAHNG---- 633
sLvkleiiitttkpLDREeqflkreqtdeseYtLtveAtDgGgpppgdss
+++tt+ L + ++++L+ ++D+G pp
mKIAA1621 634 -------EVRTTRLLSERDV---------PKHRLVLLVKDNGDPP----- 662
ptrksqqtpplsstatvtvtVlDvNDNaP<-*
+s+++t++v V+D +
mKIAA1621 663 ----------RSASVTLHVLVVDGFSQPY 681
//