hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm10269/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1592  ( 795 res)   mpm10269

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N 
--------     -----------                                -----    ------- ---
DUF21        Domain of unknown function DUF21           171.3    1.6e-47   1
CBS          CBS domain pair                             45.5    1.2e-09   1
cNMP_binding Cyclic nucleotide-binding domain             7.7       0.42   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
DUF21          1/1     205   379 ..     1   208 []   171.3  1.6e-47
CBS            1/1     398   525 ..     1   114 []    45.5  1.2e-09
cNMP_binding   1/1     612   745 ..     1   100 []     7.7     0.42

Alignments of top-scoring domains:
DUF21: domain 1 of 1, from 205 to 379: score 171.3, E = 1.6e-47
                   *->lllliillLillsaFFSasEfALvslrrsrleqlaesGdp.EK.hKk
                      l +l++ +L++ls++FS++ ++L++l++ +l+ +++ G+++E+++  
   mKIAA1592   205    LHILLVMVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEkERkY-- 249  

                   gAkralkllenpdrllLstiqlGiTlvnilaGavGEpaiatllapllggl
                    A+++++++++ + l L++++lG++lvn+         +++ll+ l+g+ 
   mKIAA1592   250 -ARKIEPIRRKGNYL-LCSLLLGNVLVNTS--------LTILLDNLIGS- 288  

                   glpenktslahaisvvlAfaliTfLilvfGElvPKsiAirypEkvAlrvA
                                  + A+a +T+ i++fGE++P+++++r++++v+++++
   mKIAA1592   289 --------------GIMAVASSTIGIVIFGEILPQALCSRHGLAVGANTI 324  

                   pplrlfyrlfyPlvwllnkasanlllrllGvepaeesesavteeElkslv
                   +++ +f++l++Pl+++++k    ll+ +lG e ++    ++ +e l +++
   mKIAA1592   325 VLTKVFMLLTFPLSFPISK----LLDFVLGQEIRT----VYNREKLMEML 366  

                   eesaeeGvleeeE<-*
                    + +   +l +eE   
   mKIAA1592   367 KVTEPYNDLVKEE    379  

CBS: domain 1 of 1, from 398 to 525: score 45.5, E = 1.2e-09
                RF    xxxxxxxxxxxxxxxxx  xxxxxxxxxxxxxxxxxx xxxxxxxxx
                   *->dvmtkdvvtvdpedttl..ealklmrengisrlPVvd.edgklvGiv
                      ++  +d ++++ +d+ l+   + ++ e+g++r+PV ++e  ++v i+
   mKIAA1592   398    MTQLHDCFMIR-SDAILdfNTMSEIMESGYTRIPVFEdEQSNIVDIL 443  

                RF xxxxxxxxxx       xxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxx
                   terDlllral.......tpvsdiMtrpPvitvppdtsl.ealelmlehgi
                    ++D l  + +++ ++ +++ ++ ++p v++v  dt l+  le + + + 
   mKIAA1592   444 YVKD-LAFVDpddctplKTITRFYNHP-VHFVFHDTKLdAMLEEFKKGKS 491  

                RF xxxxxxxxxx         xxxxxxxxxxxxxxxxxx   
                   rhrrlpVvDe.........dgklvGivtreDilrala<-*
                    h +++V  + ++++++++  +++G+vt+eD++++++   
   mKIAA1592   492 -H-LAIVQ-KvnnegegdpFYEVLGLVTLEDVIEEII    525  

cNMP_binding: domain 1 of 1, from 612 to 745: score 7.7, E = 0.42
                   *->lelrsfkkGevifreGdpadslYivlsGkvkvyk.dedgreq.....
                       e+ +++  ++++  + pad++ ++l+Gkv+v+ + e+ +  ++  +
   mKIAA1592   612    NEHNRYCVRHYLYTRNKPADCFVLILQGKVEVEAgKENMKFEtgafs 658  

                   .....................................ilgilgpGdffGe
                     ++   +  ++++++  +++ +++ + + ++++++ +   l     fG 
   mKIAA1592   659 yygtmalsvappdrspalptplsrsaslsypdrntdlTSTSLAGSNQFGS 708  

                   lallggendspSrhaprsatvvAltdsellvipredflelleedpe<-*
                     l +           + ++v+Altd + + i r++ ++ l+ +     
   mKIAA1592   709 CILGQYV---------SDFSVRALTDLQYIKITRQQYQNGLMASRM    745  

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