hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbh/mbh04724/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1589  ( 775 res)   mbh04724

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
FYVE     FYVE zinc finger                               105.2    1.3e-27   2
zf-B_box B-box zinc finger                                3.6       0.32   1
GBP      Guanylate-binding protein, N-terminal domain   -91.5        0.5   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
zf-B_box   1/1      69   122 ..     1    46 []     3.6     0.32
GBP        1/1     160   404 ..     1   289 []   -91.5      0.5
FYVE       1/2     594   661 ..     1    77 []    62.1  1.2e-14
FYVE       2/2     708   774 ..     1    77 []    51.1  2.5e-11

Alignments of top-scoring domains:
zf-B_box: domain 1 of 1, from 69 to 122: score 3.6, E = 0.32
                   *->ervC......peHg....ekaslfCedDqalLCvvCdesgeHsankl
                       ++C++ +++  H ++ +++a + C+++   LC +C+    H   + 
   mKIAA1589    69    VPYCdpckgpNGHSpgvrQRAAVRCQTCKINLCLECQKR-TH-SGGN 113  

                   argHtvvpl<-*
                    r+H +      
   mKIAA1589   114 KRRHPITVY    122  

GBP: domain 1 of 1, from 160 to 404: score -91.5, E = 0.5
                   *->dgqlelNeeALeiLLlsesaitqpVvVVaivGlyRtGKSfLmN..kL
                      + q +  e+ +++L   + + +q + VV+i G    GKS  +N++++
   mKIAA1589   160    EIQVTNEEDFIRKL---DCKPDQHLKVVSIFGNTGDGKSHTLNhtFF 203  

                   agYlynkdssdWlggnsekntGFslgsTveseTkGIwmWcvpflidhpnk
                    g                 ++ F   +  es+T G+w   +p        
   mKIAA1589   204 YG-----------------REVFKTSPAQESCTVGVWAAYDP-------- 228  

                   pevtLvLLDTeGlgDveksdnkndawIFALavL.LSStfVYNsmgtIneq
                     + +   DTeGl       n +  +   L vL +S   +Y +     + 
   mKIAA1589   229 -VHKVAVIDTEGLLGATV--NLSQRTRLLLKVLaISDLVIYRTHADRLHN 275  

                   aLdqL......hlVTELTelIRakssPdegrvadssefvsfFPdfvWtvR
                   +L +  ++ ++ +    T+ ++a       r  +   ++   P  +    
   mKIAA1589   276 DLFKFlgdaseAYLKHFTKELKAT----TARCGLDVPLSTLGPAVI---- 317  

                   DFsLeLeldggaitgdeyLenaLklsqgqheelqnsNelRecIrkfFpkr
                      +   +  + +++d   e   kl+q    +l+ + e   +I++  ++ 
   mKIAA1589   318 --IFHETVHTQLLGSDHPSEAPEKLIQDRFRKLGRFPEAFSSIHYKGTR- 364  

                   kCFvfdrPglkkkllpqleelredeLdpeFkeqldafcsyifspeskvkt
                      +   P++   l   le+     L ++    +      if+     k 
   mKIAA1589   365 ---TYNPPTDFSGLRRALEQ-----LLENNTTRSPRHPGVIFK---ALKA 403  

                   l<-*
                   l   
   mKIAA1589   404 L    404  

FYVE: domain 1 of 2, from 594 to 661: score 62.1, E = 1.2e-14
                   *->phWvpDeevsnCmrCgkpFtkltkRrHHCRaCGrifCgsCssktvll
                      ++W p +   +C++C ++F    + +HHCRaCG  fC+sCsskt ++
   mKIAA1589   594    AYWRPNSQILSCNQCATSFK-DNDTKHHCRACGEGFCDSCSSKTRPV 639  

                   pylgiaallkndviekpvRVCdsCydrlnk<-*
                   p+ g            pvRVCdsCyd  n    
   mKIAA1589   640 PERGW--------GPAPVRVCDSCYDARNV    661  

FYVE: domain 2 of 2, from 708 to 774: score 51.1, E = 2.5e-11
                   *->phWvpDeevsnCmrCgkpFtkltkRrHHCRaCGrifCgsCssktvll
                      ++WvpD e  +C++C+k+F+ +   +HHCRaCG+ fC++Cs    ++
   mKIAA1589   708    AYWVPDHEILHCHNCRKEFS-VKLSKHHCRACGQGFCDECSHDCRAV 753  

                   pylgiaallkndviekpvRVCdsCydrlnk<-*
                   p+ g            pvRVC +C+    +   
   mKIAA1589   754 PSRGW---------DHPVRVCFNCNKKPGD    774  

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