hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj24085/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1562  ( 1135 res)   mfj24085

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
Cadherin   Cadherin domain                              302.3    5.9e-87   5
Cadherin_2 Cadherin-like                                 34.1      4e-08   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
Cadherin_2   1/1      29   115 ..     1    84 []    34.1    4e-08
Cadherin     1/5     143   238 ..     1   107 []    59.4  7.6e-14
Cadherin     2/5     252   346 ..     1   107 []    86.6  5.2e-22
Cadherin     3/5     366   457 ..     1   107 []    54.5  2.4e-12
Cadherin     4/5     471   568 ..     1   107 []    73.0  6.3e-18
Cadherin     5/5     587   678 ..     1   107 []    35.2  1.5e-06

Alignments of top-scoring domains:
Cadherin_2: domain 1 of 1, from 29 to 115: score 34.1, E = 4e-08
                   *->gqirYSVpEEterGsfVGNl...AKDLGLdvqeLaaRgaRivSggnk
                        + Y + EE   Gs+++ l++++ D  L +   +a ++R   +gn 
   mKIAA1562    29    KNLKYRIYEEQRVGSVIARLsedVADVLLKLPNPSAVRFRAMPRGNS 75   

                   qyFqlnletGdLlvnERiDREeLCgqsepCvLhlevllEn<-*
                   +++ +n +tG+  +  +iDRE+LC +   C+++++vl      
   mKIAA1562    76 PLLVVNENTGEISIGAKIDREQLCQKNLNCSIEFDVLTLP    115  

Cadherin: domain 1 of 5, from 143 to 238: score 59.4, E = 7.6e-14
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFr
                       +++++E a+vGt++    A D+D   g N+  +Ys++ ++    F 
   mKIAA1562   143    IPIEISESAAVGTRIPLDSAFDPD--VGENSLHTYSLSAND---YFN 184  

                   IdpdtGdnegi....isttkpLDREeifngeYeLtveAtDadpllasggg
                   I+ +t + +g++  ++ ++k+LDRE      YeL + A+D+       g 
   mKIAA1562   185 IEVRTRT-DGAkyaeLIVVKELDRELK--ASYELQLTASDM-------GV 224  

                   pplsstatvtitVl<-*
                   p +s+   + i++    
   mKIAA1562   225 PQRSGSSILKISIS    238  

Cadherin: domain 2 of 5, from 252 to 346: score 86.6, E = 5.2e-22
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnp...gg
                      y++++ En+pvGt +l ++AtD+D  +g+Ngri+Ys++++ +++   
   mKIAA1562   252    YTIQLLENSPVGTLLLDLNATDPD--EGANGRIVYSFSSHVSpkiIE 296  

                   wFrIdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgggp
                   +F+Id++ G     +++ kp+D+E +    Ye+ v A+D        g+ 
   mKIAA1562   297 TFKIDSEKGH----LTLFKPVDYEIT--KSYEIDVQAQDL-------GPN 333  

                   plsstatvtitVl<-*
                   +  + + ++i+V    
   mKIAA1562   334 SIPAHCKIIIKVV    346  

Cadherin: domain 3 of 5, from 366 to 457: score 54.5, E = 2.4e-12
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFr
                       +  v E+ p+ t+v+ v+++D+D  +g+Ng i  ++ g++   +F+
   mKIAA1562   366    EVSYVFEGDPIDTFVAIVRVQDKD--SGLNGEIICKLHGHG---HFK 407  

                   IdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgggppls
                   +++ t +n  +i t + LDRE++  +eY+Ltv+A D        g+p+ls
   mKIAA1562   408 LQK-TYENNYLILTNATLDREKR--SEYSLTVIAEDK-------GTPSLS 447  

                   statvtitVl<-*
                   s+   t+++    
   mKIAA1562   448 SVRHFTVQIN    457  

Cadherin: domain 4 of 5, from 471 to 568: score 73.0, E = 6.3e-18
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnp.....
                      y++ ++En ++G  ++tvtAtD+D  lg Ng ++Y il+  + +++ 
   mKIAA1562   471    YEFVISENNSPGAYITTVTATDPD--LGENGHVTYTILESFVlgssi 515  

                   ggwFrIdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgg
                       +Idp +G     i+  +  D Ee   ++ +++veA+D+      g 
   mKIAA1562   516 TTYVTIDPSNGA----IYALRIFDHEEV--SQITFVVEARDG------GS 553  

                   gpplsstatvtitVl<-*
                   ++ lss +tv+ t++   
   mKIAA1562   554 QKQLSSNTTVVLTII    568  

Cadherin: domain 5 of 5, from 587 to 678: score 35.2, E = 1.5e-06
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFr
                       ++s+p +a +G +v++++++D+D  +g+N+  + si++gn++++F 
   mKIAA1562   587    AEISIPKGAESGFHVTRIRVVDRD--SGANAEFSCSIVSGNEENIFI 631  

                   IdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgggppls
                   +dp++ d    i t   +  E+i+  e  L+v+ +D        g+ppl 
   mKIAA1562   632 MDPRSCD----IHTN--VSMESIPSTEWALSVIIQDK-------GSPPLH 668  

                   statvtitVl<-*
                   + + +++ V    
   mKIAA1562   669 TKVLLRCMVF    678  

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