hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/Pfam Sequence file: /cdna4/rodent/full/goal/mpm/mpm11207/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA1521 ( 1446 res) mpm11207 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- VPS9 Vacuolar sorting protein 9 (VPS9) domain 194.6 1.5e-54 1 RasGAP GTPase-activator protein for Ras-like GTPase -1.5 1e-05 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- RasGAP 1/1 162 364 .. 1 231 [] -1.5 1e-05 VPS9 1/1 1342 1444 .. 1 120 [] 194.6 1.5e-54 Alignments of top-scoring domains: RasGAP: domain 1 of 1, from 162 to 364: score -1.5, E = 1e-05 *->LvktllqkEIeSkaddpttlfRgNslaskmleqyf....RrarGneY ++ l+ E++ +d p l+R+ ++a +l +f+++ ++a + mKIAA1521 162 VLRYLIEFELK-ESDNPRRLLRRGTCAFSILFKLFseglFSA--KLF 205 LrktL.rpvLkeIieskdWqHLscEiDPlkvykklVNqgelstsE..... L tL+ p+ + +e+ d +E+DP k+ E+ ++ mKIAA1521 206 LTATLhEPIMQLLVEDED----HLETDPNKL------------IErfspa 239 ldydlTnEevld..eeekseaieenlrnLlkyteklleaItsSsdefPpe l E +d+ ++ e +++n + L+++++k++ + fP mKIAA1521 240 QQEKLFGEKGSDrfRQKVQEMVDSNEAKLVALVNKFIGYLKQNTYCFPHS 289 LryIckclrqsa.cekFPdnatVKEKKENKKSVVSqRFeqvilsavGgfv Lr+I ++ ++c+ ++ + + ++ mKIAA1521 290 LRWIVSQMYKTLsCVDRLEVG-------------------EVRAMCTDLL 320 FLRFinPAIvsPdlfnIidkspsaqaTTDqrR.tLtliAKviQslANg<- Fi+PA v+P +Ii++ p ++ +R +L + +Q lA mKIAA1521 321 LACFICPAVVNPEQYGIISDAPINEV----ARfNLMQVGRLLQQLAMT 364 * mKIAA1521 - - VPS9: domain 1 of 1, from 1342 to 1444: score 194.6, E = 1.5e-54 *->veeakqeLrelqYeyySPrdKlqcllrccklIfnalknakgeneaPT +++a++e+r+++ +y++PrdK+qc+lr+c++I+n+l++a++++ mKIAA1521 1342 WPSAQSEIRTIS-AYKTPRDKVQCILRMCSTIMNLLSLANEDS---- 1383 DPmCGYRGepsADdfLPlLiYvilkanpphLlsnieYisrFlnpPisrlL +p+ADdf+P+L++v++kanpp+Lls+++Yis+F++ s +L mKIAA1521 1384 --------VPGADDFVPVLVFVLIKANPPCLLSTVQYISSFYA---S-CL 1421 sGEegYYLTsLeaAlaFIkslde<-* sGEe+Y++++++aA++FIk++d+ mKIAA1521 1422 SGEESYWWMQFTAAVEFIKTIDD 1444 //