hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbh/mbh00594/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1520  ( 782 res)   mbh00594

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N 
--------     -----------                                -----    ------- ---
ABC_membrane ABC transporter transmembrane region       198.4    1.1e-55   1
ABC_tran     ABC transporter                            184.6    1.6e-51   1
SMC_N        RecF/RecN/SMC N terminal domain           -113.6      0.017   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
ABC_membrane   1/1     204   475 ..     1   286 []   198.4  1.1e-55
ABC_tran       1/1     548   732 ..     1   206 []   184.6  1.6e-51
SMC_N          1/1     537   741 ..     1   243 []  -113.6    0.017

Alignments of top-scoring domains:
ABC_membrane: domain 1 of 1, from 204 to 475: score 198.4, E = 1.1e-55
                   *->lligilllilagatalvtfplllgrfldsgfplsdgnddhearssli
                      l+++ ++li+a + + +  p+++gr +ds   +  ++  +++  + +
   mKIAA1520   204    LVAASFFLIVAALGETF-LPYYTGRAIDS---IVIQKSMDQFTTAVV 246  

                   slailsllavfvlqglllqgsfyllagerlgqrlrkrlfrallrqilglf
                    +++l ++++ ++ g+  ++++ +  + rl++rlr++lfr+l+ q+ ++f
   mKIAA1520   247 VVCLL-AIGSSLAAGIRGGIFTLV--FARLNIRLRNCLFRSLVSQETSFF 293  

                   dsffdtnsvGeltsRltnDvskirdglgdklgllfqslatvvgglivmfy
                   d+    n++G+l sRlt+D+ +++d++++++ +++++ + v g++++mf 
   mKIAA1520   294 DE----NRTGDLISRLTSDTTMVSDLVSQNINIFLRNTVKVTGVVVFMFS 339  

                   yswkLtLvllailpllillsavlakklrklnrkeqkayakagsvaeEsls
                   +sw+L+Lv++  +p+++++s +++k  ++l++++q+a a a++ aeE++s
   mKIAA1520   340 LSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQSALARASTTAEETIS 389  

                   girTVkafgrEeyelerydkaledaekagikkaiiagllfgitqlisyls
                   +++TV++f++Ee e e +  +l+ ++k  +k a++++    ++ l  +++
   mKIAA1520   390 AMKTVRSFANEEEEAEVFLRKLQQVYKLNRKEAAAYMSYVWGSGLTLLVV 439  

                   yalalwfGgylvasvisgglsvgtlfaflslgnqltgpl<-*
                   ++ +l++Gg+l   visg++s+g+l+af+ +  +l       
   mKIAA1520   440 QVSILYYGGHL---VISGQMSSGNLIAFIIYEFVLGDCM    475  

ABC_tran: domain 1 of 1, from 548 to 732: score 184.6, E = 1.6e-51
                RF    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   *->GevvalvGpNGaGKSTLLklisGllqiPdrteGeilidpGedltdls
                      G+v+alvGp+G+GKS+  +++  +++    + G++l+d G+++  ++
   mKIAA1520   548    GKVTALVGPSGSGKSSCVNILENFYP-L--QGGRVLLD-GKPIGAYD 590  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   lealrklgrigvvpQdpqlflnptlTvrenlafglrlkgplekeerdefa
                   + +l+++  i+ v+Q+p lf     ++ +n+ +gl+              
   mKIAA1520   591 HKYLHRV--ISLVSQEPVLF---ARSITDNISYGLPTV-----------P 624  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxx
                   darveeaLervGladlldrlpqglDt.lgdgggtLSGGqkQRvalARaLl
                    + v ea+ +++ + ++  l++g+ t+ g+ g++LSGGqkQRva ARaL+
   mKIAA1520   625 FEMVVEAAQKANAHGFIMELQDGYSTeTGEKGAQLSGGQKQRVAMARALV 674  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   tkpklLlLDEPTagLDpasraqllellrelrqrggtvllitHdlefvdrl
                   ++p++L+LDE+T++LD++s+  ++++++   q   tvl+i H+l  v+r 
   mKIAA1520   675 RNPPVLILDEATSALDAESEYLIQQAIHGNLQ-RHTVLIIAHRLSTVER- 722  

                RF xxxxxxxxxx   
                   adrilvlenG<-*
                   a  i+vl++G   
   mKIAA1520   723 AHLIVVLDKG    732  

SMC_N: domain 1 of 1, from 537 to 741: score -113.6, E = 0.017
                RF    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   *->ylkrielegFKSYagktiigpFspgFtaIvGPNGSGKSNiiDAIlFV
                           +l++  S+     ++  ++ +ta+vGP GSGKS+ +  +   
   mKIAA1520   537    -----VLQNV-SF-----SLSPGK-VTALVGPSGSGKSSCVNIL--- 568  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   LGersakkLRaeklsdLIhaGsksgasvnsAeVtitFlvqkivdnedkkh
                        +            ++      +++ ++V +    +k++  +d+k 
   mKIAA1520   569 ----EN------------FY------PLQGGRVLLD---GKPIGAYDHK- 592  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   iNSpflpideeeevsItRrvyrdGdqYSeYyINGknvtkIkdvseLLesa
                                +  +    ++ +    +++ +        +s  L+ +
   mKIAA1520   593 -------------YLHRVISLVSQE---PVLFARSITDN---ISYGLPTV 623  

                RF xxxxx                             xxxxxxxxxxxxxxxx
                   GIske.............................nLSGGEKtLaALALlF
                    + +  +  ++ +      ++++    +  ++  +LSGG+K  +A+A + 
   mKIAA1520   624 PFEMVveaaqkanahgfimelqdgystetgekgaQLSGGQKQRVAMA-R- 671  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   AQGEyliqkykPaPFYvlDEiDAALDeaNvsrvAnyiktelsknaQFIVI
                   A        ++  P  +lDE  +ALD++   ++ + i+ +l++ + +++I
   mKIAA1520   672 A-------LVRNPPVLILDEATSALDAESEYLIQQAIHGNLQRHT-VLII 713  

                RF xxxxxxxxxx   xxxxxxxxxxxxxxx   
                   slReemfekA...drlvGvymvengvst<-*
                   ++R  ++e A+   +l   + v++g+ +   
   mKIAA1520   714 AHRLSTVERAhliVVLDKGRVVQQGTHQ    741  

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