hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg09342/w3open/interpro/cnk_1/seq.in
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  mKIAA1516  ( 1364 res)   mbg09342

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PI-PLC-X Phosphatidylinositol-specific phospholipase    245.3    8.3e-70   1
PI-PLC-Y Phosphatidylinositol-specific phospholipase    134.6    1.7e-36   1
RA       Ras association (RalGDS/AF-6) domain            77.3    3.1e-19   2
C2       C2 domain                                       58.9    1.1e-13   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PI-PLC-X   1/1     456   604 ..     1   153 []   245.3  8.3e-70
PI-PLC-Y   1/1     806   908 ..     1   128 []   134.6  1.7e-36
C2         1/1     933  1015 ..     1    88 []    58.9  1.1e-13
RA         1/2    1074  1176 ..     1    98 []     0.2      4.6
RA         2/2    1197  1300 ..     1    98 []    77.3  3.2e-19

Alignments of top-scoring domains:
PI-PLC-X: domain 1 of 1, from 456 to 604: score 245.3, E = 8.3e-70
                   *->dmsiPLsHYfisSshntYLtgkQlwGkssvesYrqqLdaGcRcvELD
                      ++  PLs+Y+i SshntYLtg+Ql+G+ssve Y q+L++GcR +ELD
   mKIAA1516   456    ELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSIELD 502  

                   cwdGkpddepiIyHGhtltleiklkdVleaIkdfafkPtSpyPvIlSlen
                   cwdG  d++piIyHGhtlt++i++k+V+eaI   af  tS  P+I+S+en
   mKIAA1516   503 CWDG-DDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFI-TSDLPIIISIEN 550  

                   HcnsddqQrkmakyfkeiFgdmLltkPtldslttepglpLPslkdlrgKI
                   Hc+ + qQrkma++fk++Fg++L+ k  l+++  +    LPs+++lr+K 
   mKIAA1516   551 HCSLP-QQRKMAEIFKSVFGEKLVAKF-LFETDFSDDPMLPSPDQLRRKV 598  

                   LLknkk<-*
                   LLknkk   
   mKIAA1516   599 LLKNKK    604  

PI-PLC-Y: domain 1 of 1, from 806 to 908: score 134.6, E = 1.7e-36
                   *->ElsnLvnYiqsikFrsFelsGeekntsyeisSFsErkvkakkllkes
                       ls+++            ++      +y+isS++E+  +ak+l    
   mKIAA1516   806    SLSAII-----------RTP-----KCYHISSLNEN--AAKRLCRRG 834  

                   pvefVkyNkrqLsRvYPkGtRvDSSNfmPqvfWnaGCQmVALNfQTsDlp
                   +  + ++   qL+R YP+ tR DSSN +P++fW  G Q+VALN+QT Dlp
   mKIAA1516   835 SQKLIQHTAYQLLRTYPAATRIDSSNPNPIMFWLHGIQLVALNYQTDDLP 884  

                   mqiNdGmFeyNggqPdGsfksGYlLKPeflR<-*
                   + +N +mFe+Ngg       +GY+LKP+ l    
   mKIAA1516   885 LHLNAAMFEANGG-------CGYVLKPPVLW    908  

C2: domain 1 of 1, from 933 to 1015: score 58.9, E = 1.1e-13
                   *->LrVtvieAknLppkDfkngksDPYVkvslggdkkd.qkkkTkvikkt
                       ++t+i+++n  p   +n++ +P  +v ++g++ d+  ++Tk i+++
   mKIAA1516   933    YSLTIISGQNVCP---SNSTGSPCIEVDVLGMPLDsCHFRTKPIHRN 976  

                   .lNPvWNEtFtFevpppdlqetLeieVyDydrfgrddflGevs<-*
                   +lNP WNE+F F v+++dl + L++ V ++++     +  + +   
   mKIAA1516   977 tLNPMWNEQFLFRVHFEDLVF-LRFAVVENNSSA---ITAQRI    1015 

RA: domain 1 of 2, from 1074 to 1176: score 0.2, E = 4.6
                   *->dsgvlrVygedgtpgtyktilvskntTaeeViralL...rKfgldad
                       ++ + V+g  g  + ++++ ++++t a+++++++L  ++  ++   
   mKIAA1516  1074    QTHKVTVHGVPGPEP-FAVFTINEGTKAKQLLQQVLavdQDTKC--- 1116 

                   dpedyvLvEvsl.vlerggeer.....rvLpddEkPlqiqlqlkrdaqvr
                   +  dy L E+        +e+r+++ +r  ++ E  +qi+  + +++++ 
   mKIAA1516  1117 TATDYFLMEEKHfISKEKNECRkqpfqRAVGPEEDIVQILNSWFPEEGYV 1166 

                   srFlLrrred<-*
                   +r++L+  ++   
   mKIAA1516  1167 GRIVLKPQQE    1176 

RA: domain 2 of 2, from 1197 to 1300: score 77.3, E = 3.2e-19
                   *->dsgvlrVygedgtpgtyktilvskntTaeeViralLrKfgl.....d
                       s+++ V++ +  ++  ++i++++ +Ta++Vi++ L+K++++ +  +
   mKIAA1516  1197    ESFFVQVHDVSPEQP-RTVIKAPRVSTAQDVIQQTLCKAKYsysilN 1242 

                   addpedyvLvEvsl.......vlerggeerrvLpddEkPlqiqlqlkrda
                   +++p+dyvL E++l++  ++++  +   +r +L+d+E+++q+q+ +k+  
   mKIAA1516  1243 NPNPCDYVLLEEVLkdaankkSSTPKSSQR-ILLDQECVFQAQSKWKG-- 1289 

                   qvrsrFlLrrred<-*
                      + F+L+ +e+   
   mKIAA1516  1290 --AGKFILKLKEQ    1300 

//