hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbf/mbf00247/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1500  ( 1728 res)   mbf00247

Scores for sequence family classification (score includes all domains):
Model     Description                                   Score    E-value  N 
--------  -----------                                   -----    ------- ---
Calx_beta Domains in Na-Ca exchangers and integrin-be   222.5    3.6e-62   5

Parsed for domains:
Model     Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------  ------- ----- -----    ----- -----      -----  -------
Calx_beta   1/5     262   366 ..     1   106 []    51.7  9.5e-11
Calx_beta   2/5     379   490 ..     1   106 []    52.8  4.6e-11
Calx_beta   3/5     505   610 ..     1   106 []    47.2  2.1e-09
Calx_beta   4/5     625   727 ..     1   106 []    19.7    0.008
Calx_beta   5/5     745   849 ..     1   106 []    63.5  2.7e-14

Alignments of top-scoring domains:
Calx_beta: domain 1 of 5, from 262 to 366: score 51.7, E = 9.5e-11
                   *->atvtilDddhagtvgFeqphytVsEsdGevevtVvRtggtargtvvV
                      ++ + +   + + ++F    y+VsE +G+v vtV+Rtg+ ++ +++V
   mKIAA1500   262    VVSDNVFHIQWSLISFKYTSYNVSEKAGSVSVTVQRTGN-LNQYAIV 307  

                   pyrTedGTAt.....aGgsDYepvdIeGtLtFepgegtekeIrikiidDd
                     rTe GTA++++++++ +DY     +G+++F+ ge + k  ++ i dDd
   mKIAA1500   308 LCRTEQGTASssshpGQ-QDYMEY--AGQVQFDEGE-STKSCTVIINDDD 353  

                   iyEerdEtFyvrLs<-*
                   ++E   E+F+v Ls   
   mKIAA1500   354 VFEN-IESFTVGLS    366  

Calx_beta: domain 2 of 5, from 379 to 490: score 52.8, E = 4.6e-11
                   *->atvtilDddhagtvgFeqphytVsEsdGevevtVvRtggtargtvvV
                      a v+i D  +  t++F+  +y+V+Es+G +  +++R+g+  ++tv+ 
   mKIAA1500   379    AKVIINDTEDEPTLEFDKKTYRVNESAGFLFAPIKRQGD-SSSTVSA 424  

                   pyrTedGTAtaGgsDYepvdIeGt............LtFepgegtekeIr
                     +T+  +A++  s Y+     G++ ++++++ +++++F+pg  t+ + +
   mKIAA1500   425 VCYTVPKSAMGS-SLYALE--SGSdfksrgrsaesrVIFGPGV-TVSTCD 470  

                   ikiidDdiyEerdEtFyvrLs<-*
                   + +idD++yEe +E F + L    
   mKIAA1500   471 VMVIDDSEYEE-EEEFEIALA    490  

Calx_beta: domain 3 of 5, from 505 to 610: score 47.2, E = 2.1e-09
                   *->atvtilDddhagtvgFeqphytVsEsdGevevtVvRtggtargtvvV
                       + +  ++d a+tv++ + ++t sE +G+v ++V+R+g +++++++V
   mKIAA1500   505    KVLISGPND-ASTVSLGNTAFTISEDAGTVKIPVIRHGTDLSTFTSV 550  

                   pyrTedG...TAtaGgsDYepvdIeGtLtFepgegtekeIrikiidDd..
                      T   ++ +At G +DY+p      ++F+pg  te++ +  i+dD + 
   mKIAA1500   551 WCATRPSdpaSATPG-VDYVPS--SRKVEFGPGI-TEQYCTLTILDDTqy 596  

                   .iyEerdEtFyvrLs<-*
                   +++E+  EtF+v Ls   
   mKIAA1500   597 pVIEG-LETFVVFLS    610  

Calx_beta: domain 4 of 5, from 625 to 727: score 19.7, E = 0.008
                   *->atvtilDddhagtvgFeqphytVsEsdGevevtVvRtggtargtvvV
                       ++ +  +d + +++F+     V+E  G++ ++++R+g+ ++   +V
   mKIAA1500   625    IAINDTFQD-VPSMQFSKDLLLVKEKEGVLHIPIIRSGD-LSYESSV 669  

                   pyrTedGTAtaGgsDYep...vdIeGtLtFepgegtekeIrikiidDdiy
                   + +T+  +A+    D+e ++++d    +tF  g+   k  ++ i dD+++
   mKIAA1500   670 RCYTQGHSAQVM-EDFEErrnAD-SSRITFLKGQ-KTKNCTVYIHDDSMF 716  

                   EerdEtFyvrLs<-*
                   E  +E+F+v L+   
   mKIAA1500   717 EP-EEQFRVYLG    727  

Calx_beta: domain 5 of 5, from 745 to 849: score 63.5, E = 2.7e-14
                   *->atvtilDddhagtvgFeqphytVs.....EsdGevevtVvRtggtar
                      atvti  d +a t++Fe+++y+V ++ ++E   ++ ++V+R+g+  +
   mKIAA1500   745    ATVTISNDEDAPTIEFEEAAYQVRepagpEAIAVLSIKVIRRGD-QN 790  

                   gtvvVpyrTedGTAtaGgsDYepvdIeGtLtFepgegtekeIrikiidDd
                    t  ++ +T dG+A+ G +DY p     +L F pg  ++ +++++i+  +
   mKIAA1500   791 RTSKIRCSTRDGSAQSG-VDYYPK--SRVLKFSPGV-DHIFFKVEILSNE 836  

                   iyEerdEtFyvrLs<-*
                     E  +E+F ++L+   
   mKIAA1500   837 DREW-HESFSLVLG    849  

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