hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm09319/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1494  ( 914 res)   mpm09319

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
SH3      Src homology 3 domains                         282.9    2.5e-80   4
RING     Ring finger                                     44.5    1.4e-08   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
RING       1/1      34    74 ..     1    23 []    44.5  1.4e-08
SH3        1/4     159   214 ..     1    58 []    76.7  2.8e-18
SH3        2/4     221   280 ..     1    58 []    65.2  8.3e-15
SH3        3/4     477   534 ..     1    58 []    81.1  1.3e-19
SH3        4/4     858   914 .]     1    58 []    63.6  2.4e-14

Alignments of top-scoring domains:
RING: domain 1 of 1, from 34 to 74: score 44.5, E = 1.4e-08
                   *->CpICle.....pvvlpCgH.FCr.Ci...........CPlC<-*
                      Cp+Cle+ + +++vlpC H+FC++C+ +  +++++ +CP C   
   mKIAA1494    34    CPVCLErldasAKVLPCQHtFCKrCLlgivgsrnelrCPEC    74   

SH3: domain 1 of 4, from 159 to 214: score 76.7, E = 2.8e-18
                   *->eyvvAlYDyeaqnedELsFkkGDiitvleksddgWweGelnrtGkeG
                      + ++AlY+ye+ ++++L F+kGDii++ +++d++W+ Ge+   G  G
   mKIAA1494   159    PCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVS--GVHG 203  

                   lfPsnYVeeie<-*
                   +fP+n+V++i+   
   mKIAA1494   204 FFPTNFVQIIK    214  

SH3: domain 2 of 4, from 221 to 280: score 65.2, E = 8.3e-15
                   *->eyvvAlYDyea....qnedELsFkkGDiitvleksddgWweGelnrt
                      ++++AlYD+e ++++ + d L+F k+D++tv++++d++W eG l   
   mKIAA1494   221    PQCKALYDFEVkdkeADKDCLPFAKDDVLTVIRRVDENWAEGMLA-- 265  

                   GkeGlfPsnYVeeie<-*
                    k+G+fP +YVe      
   mKIAA1494   266 DKIGIFPISYVEFNS    280  

SH3: domain 3 of 4, from 477 to 534: score 81.1, E = 1.3e-19
                   *->eyvvAlYDyeaqnedELsFkkGDiitvleksddgWweGelnrtGkeG
                       ++vA+Y+y+++ edEL ++kG++++v e++ dgW++G+  +t k+G
   mKIAA1494   477    SVYVAIYPYTPRKEDELELRKGEMFLVFERCQDGWYKGTSMHTSKIG 523  

                   lfPsnYVeeie<-*
                    fP+nYV++++   
   mKIAA1494   524 VFPGNYVAPVT    534  

SH3: domain 4 of 4, from 858 to 914: score 63.6, E = 2.4e-14
                   *->eyvvAlYDyeaqnedELsFkkGDiitvleksddgWweGelnrtGkeG
                      e+ +++ +y +q+e EL +k+GDi+ v++k +dgW++G+l+r+Gk+G
   mKIAA1494   858    ERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTG 904  

                   lfPsnYVeeie<-*
                   lfP+++V e     
   mKIAA1494   905 LFPGSFV-ENI    914  

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