hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm09319/w3open/interpro/cnk_1/seq.in
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  mKIAA1494  ( 914 res)   mpm09319

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
SH3_1    SH3 domain                                     233.5      3e-66   4
SH3_2    Variant SH3 domain                             120.3    3.6e-32   4
zf-C3HC4 Zinc finger, C3HC4 type (RING finger)           38.6    1.4e-07   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
zf-C3HC4   1/1      34    74 ..     1    50 []    38.6  1.4e-07
SH3_2      1/4     160   213 ..     1    69 []    34.9  1.8e-06
SH3_1      1/4     159   213 ..     1    58 []    66.3  6.5e-16
SH3_2      2/4     222   278 ..     1    69 []    12.2     0.33
SH3_1      2/4     221   279 ..     1    58 []    44.8  1.9e-09
SH3_1      3/4     477   533 ..     1    58 []    71.0  2.5e-17
SH3_2      3/4     478   533 ..     1    69 []    39.2  9.4e-08
SH3_1      4/4     858   914 .]     1    58 []    54.0  3.2e-12
SH3_2      4/4     859   914 .]     1    69 []    38.2  1.9e-07

Alignments of top-scoring domains:
zf-C3HC4: domain 1 of 1, from 34 to 74: score 38.6, E = 1.4e-07
                   *->CrICleelkepsndfplilpCgHsGslkyfCrsClerwlsssgnttC
                      C++Cle l+        +lpC H+     fC+ Cl+  + s+++  C
   mKIAA1494    34    CPVCLERLDASA----KVLPCQHT-----FCKRCLLGIVGSRNELRC 71   

                   plC<-*
                   p C   
   mKIAA1494    72 PEC    74   

SH3_2: domain 1 of 4, from 160 to 213: score 34.9, E = 1.8e-06
                   *->ygraiedyvaAtdknenleeeeLslkkGdvvkvidvggskdddgwwl
                       ++a+ +y++   +++      L + kGd++ +      + d++w++
   mKIAA1494   160    CAKALYNYEG-KEPGD------LKFSKGDIIILR----RQVDENWYH 195  

                   geslggGrrrRGlvPssaveel<-*
                   ge+   G+   G++P+++v+++   
   mKIAA1494   196 GEV--SGVH--GFFPTNFVQII    213  

SH3_1: domain 1 of 4, from 159 to 213: score 66.3, E = 6.5e-16
                   *->kkvvALYDYearesdELsFkkGDvitvleksddgWWkgrlkgtgGke
                      + ++ALY Ye+ e+++L F kGD+i++  ++d++W+ g++    G  
   mKIAA1494   159    PCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVS---GVH 202  

                   GliPsNYVepv<-*
                   G++P+N+V+ +   
   mKIAA1494   203 GFFPTNFVQII    213  

SH3_2: domain 2 of 4, from 222 to 278: score 12.2, E = 0.33
                   *->ygraiedyvaAtdknenleeeeLslkkGdvvkvidvggskddd.gww
                       ++a+ d++   dk++   +  L + k+dv+ vi     ++ d++w 
   mKIAA1494   222    QCKALYDFEV-KDKEA--DKDCLPFAKDDVLTVI-----RRVDeNWA 260  

                   lgeslggGrrrRGlvPssaveel<-*
                   +g++    +   G +P s+v e    
   mKIAA1494   261 EGML--ADKI--GIFPISYV-EF    278  

SH3_1: domain 2 of 4, from 221 to 279: score 44.8, E = 1.9e-09
                   *->kkvvALYDYeare....sdELsFkkGDvitvleksddgWWkgrlkgt
                      ++++ALYD+e  +++ + d L+F k Dv+tv+ ++d++W +g l   
   mKIAA1494   221    PQCKALYDFEVKDkeadKDCLPFAKDDVLTVIRRVDENWAEGMLA-- 265  

                   gGkeGliPsNYVepv<-*
                    +k G++P +YVe +   
   mKIAA1494   266 -DKIGIFPISYVEFN    279  

SH3_1: domain 3 of 4, from 477 to 533: score 71.0, E = 2.5e-17
                   *->kkvvALYDYearesdELsFkkGDvitvleksddgWWkgrlkgtgGke
                       ++vA+Y+Y++r +dEL ++kG+ + v e+  dgW+kg +  t+ k 
   mKIAA1494   477    SVYVAIYPYTPRKEDELELRKGEMFLVFERCQDGWYKGTSMHTS-KI 522  

                   GliPsNYVepv<-*
                   G +P NYV+pv   
   mKIAA1494   523 GVFPGNYVAPV    533  

SH3_2: domain 3 of 4, from 478 to 533: score 39.2, E = 9.4e-08
                   *->ygraiedyvaAtdknenleeeeLslkkGdvvkvidvggskdddgwwl
                      +++ai  y++ ++++e      L l+kG+ + v+    ++ +dgw+ 
   mKIAA1494   478    VYVAIYPYTP-RKEDE------LELRKGEMFLVF----ERCQDGWYK 513  

                   geslggGrrrRGlvPssaveel<-*
                   g+s    +   G++P ++v+++   
   mKIAA1494   514 GTSMHTSKI--GVFPGNYVAPV    533  

SH3_1: domain 4 of 4, from 858 to 914: score 54.0, E = 3.2e-12
                   *->kkvvALYDYearesdELsFkkGDvitvleksddgWWkgrlkgtgGke
                      ++ ++   Y+++++ EL +k+GD+++v++k +dgW kg l+++g k+
   mKIAA1494   858    ERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNG-KT 903  

                   GliPsNYVepv<-*
                   Gl+P ++Ve +   
   mKIAA1494   904 GLFPGSFVENI    914  

SH3_2: domain 4 of 4, from 859 to 914: score 38.2, E = 1.9e-07
                   *->ygraiedyvaAtdknenleeeeLslkkGdvvkvidvggskdddgwwl
                      ++r++ +y + +++ e      L lk+Gd+v v     +k+ dgw  
   mKIAA1494   859    RHRVVVSYPP-QSEAE------LELKEGDIVFVH----KKREDGWFK 894  

                   geslggGrrrRGlvPssaveel<-*
                   g++  +G++  Gl+P s+ve++   
   mKIAA1494   895 GTLQRNGKT--GLFPGSFVENI    914  

//