hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mph/mph01025/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1489  ( 627 res)   mph01025

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
BTB      BTB/POZ domain                                 130.7    2.6e-35   1
BACK     BTB And C-terminal Kelch                       127.0    3.5e-34   1
Kelch_1  Kelch motif                                     92.7    7.5e-24   4
Kelch_2  Kelch motif                                     39.9    5.8e-08   2

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
BTB        1/1      25   132 ..     1   135 []   130.7  2.6e-35
BACK       1/1     137   238 ..     1   103 []   127.0  3.5e-34
Kelch_1    1/4     309   371 ..     1    45 []    13.7     0.75
Kelch_1    2/4     373   420 ..     1    45 []    46.5  6.1e-10
Kelch_2    1/2     373   420 ..     1    54 []    24.2   0.0031
Kelch_1    3/4     422   460 ..     1    45 []     2.3       14
Kelch_1    4/4     462   520 ..     1    45 []    31.4  2.1e-05
Kelch_2    2/2     462   520 ..     1    54 []    15.7      1.1

Alignments of top-scoring domains:
BTB: domain 1 of 1, from 25 to 132: score 130.7, E = 2.6e-35
                   *->lnelreqgelcDVtLvvgdgsgrydvgkkfkAHKavLaacSpYFkal
                      l+ ++eq  ++D++L v+        g +f++HK+vLa cS+YF+a+
   mKIAA1489    25    LKLFYEQQLFTDIVLIVE--------GTEFPCHKMVLATCSSYFRAM 63   

                   FtgqfkesiteeessvsseieledvspedfealLefiYtgelsitqdqks
                   F ++       +es+++ ++ l++v++ ++++++ ++Ytg l ++     
   mKIAA1489    64 FMSG------LSESKQT-HVHLRNVDAAALQMIIAYAYTGNLAVN----- 101  

                   PssckseenvedlLalAadllqipslvdkCeefliksl<-*
                         +++ve+l ++A ++lq++++ + C e+lik++   
   mKIAA1489   102 ------DSTVEQLYETA-CFLQVEDVLQRCREYLIKKI    132  

BACK: domain 1 of 1, from 137 to 238: score 127.0, E = 3.5e-34
                   *->CLgIrrfAdaygceeLaeaAdrfilqnFleVakseEFlqLskeqLie
                      C+ +++fAd ++ceeL+++A+r++++ F++V+++e F+qLs++ Li+
   mKIAA1489   137    CVRLLSFADLFSCEELKQSAKRMVEHKFTAVYRQEAFMQLSHDLLID 183  

                   lLssDeLnVpsEeeVfeAvmrWvkhdvenRkkhlpeLLshVRLpLLspky
                   +LssD LnV++Ee+V eA+m W+ ++ e+R ++l+ +Ls++R+  Ls+  
   mKIAA1489   184 ILSSDNLNVEKEETVREAAMLWLEYNTESRSQYLSSVLSQIRIDALSEVT 233  

                   Llevve<-*
                    ++++    
   mKIAA1489   234 -QRAWF    238  

Kelch_1: domain 1 of 4, from 309 to 371: score 13.7, E = 0.75
                   *->pRsgagvvvldgkiYviGGydg..................qslnsve
                           +vv+ d+ iY++GG+ + ++++++++++++ ++  + +n+++
   mKIAA1489   309    LHKVGTVVTPDNDIYIAGGQVPlkntktnhsktsklqtafRTVNCFY 355  

                   vYDpetntWtklpsmp<-*
                    +D   ntW + ++m    
   mKIAA1489   356 WFDAQQNTWFPKTPML    371  

Kelch_1: domain 2 of 4, from 373 to 420: score 46.5, E = 6.1e-10
                   *->pRsgagvvvldgkiYviGGydg...qslnsvevYDpetntWtklpsm
                       R+  + v+++g+iY+iGG + +++   ++ve+YD+e+++Wt+++++
   mKIAA1489   373    VRVKPSLVCCEGYIYAIGGDSVggeLNRRTVERYDTEKDEWTMVSPL 419  

                   p<-*
                   p   
   mKIAA1489   420 P    420  

Kelch_2: domain 1 of 2, from 373 to 420: score 24.2, E = 0.0031
                   *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW
                       r+  ++v+++g +y +GG       + +g +  +++ ++d+e+ +W
   mKIAA1489   373    VRVKPSLVCCEGYIYAIGGD------SVGGELNRRTVERYDTEKDEW 413  

                   eklpalp<-*
                   + +++lp   
   mKIAA1489   414 TMVSPLP    420  

Kelch_1: domain 3 of 4, from 422 to 460: score 2.3, E = 14
                   *->pRsgagvvvldgkiYviGGydgqslnsvevYDpetntWtklpsmp<-
                      +    ++vv++++iYv+       ln  ++Y p++++W +++  +  
   mKIAA1489   422    AWQWSAAVVVHDCIYVM------TLNLMYCYFPRSDSWVEMAMRQ   460  

                   *
                    
   mKIAA1489     -   -    

Kelch_1: domain 4 of 4, from 462 to 520: score 31.4, E = 2.1e-05
                   *->pRsgagvvvldgkiYviGGydg..............qslnsvevYDp
                       Rs+a+++++++ki+ iGG    ++++ + ++++ + s+ +ve+YD+
   mKIAA1489   462    SRSFASAAAFGDKIFYIGGLHIatnsgirlpsgtvdGSSVTVEIYDV 508  

                   etntWtklpsmp<-*
                    +n+W++ ++ p   
   mKIAA1489   509 NKNEWKMAANIP    520  

Kelch_2: domain 2 of 2, from 462 to 520: score 15.7, E = 1.1
                   *->pryphasvvpggklyvvGGs....fkgnrgtgngde.sssdllvldp
                      +r+  +++  g+k++ +GG +  ++ g r + + +++ss ++ ++d 
   mKIAA1489   462    SRSFASAAAFGDKIFYIGGLhiatNSGIRLPSGTVDgSSVTVEIYDV 508  

                   etnvWeklpalp<-*
                   ++n+W+  + +p   
   mKIAA1489   509 NKNEWKMAANIP    520  

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