hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg07853/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1480  ( 876 res)   mbg07853

Scores for sequence family classification (score includes all domains):
Model         Description                               Score    E-value  N 
--------      -----------                               -----    ------- ---
COesterase    Carboxylesterase                          725.9   1.8e-214   1
Abhydrolase_3 alpha/beta hydrolase fold                 -64.3      0.011   1

Parsed for domains:
Model         Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
Abhydrolase_3   1/1     231   446 ..     1   247 []   -64.3    0.011
COesterase      1/1      47   652 ..     1   591 []   725.9 1.8e-214

Alignments of top-scoring domains:
Abhydrolase_3: domain 1 of 1, from 231 to 446: score -64.3, E = 0.011
                   *->lvYfHGGGFvlGsldthYdalcrrLAaragavVvSVDYR......LA
                      +vY+HGG ++ G+ ++  d  +   A++ +++V+  +YR +  + L+
   mKIAA1480   231    MVYIHGGSYMEGTGNMI-DGSVL--ASYGNVIVITLNYRvgvlgfLS 274  

                   PEhpfPA...AvdDayaAlrWlaehavgsggeddpwlelgaDpsriavaG
                          ++  + D   AlrW+ e+          +  +g+Dp+ri+v+G
   mKIAA1480   275 TGDQAAKgnyGLLDQIQALRWVSENI---------A-FFGGDPRRITVFG 314  

                   DSAGGNLAaavAqlrardrGgplaeldpdlspvrpagqvLiyPfFggtDl
                      G+  +  ++ l  +++G+ +            ++++       ++  
   mKIAA1480   315 SGIGASCVSLLT-LSHHSEGLFQ------------RAIIQSGS---AL-- 346  

                   rertesesyrlsrey.adgplL..........trdamdwfwrlYLpgadr
                          s+  +++    + lL ++ + +  +t d++d  ++ ++ +   
   mKIAA1480   347 ------SSWAVNYQPvKYTSLLadkvgcnvldTVDMVDCLRQKSAKELVE 390  

                   ddPas.lasPlfapaspdlegLsGLPPalvvvAefDpLrDegeaYAerLr
                    d  + + +  f+p   d +   + P  l+  +ef       + Y  +L 
   mKIAA1480   391 QDIQPaRYHVAFGPVI-DGDVIPDDPEILMEQGEF-------LNYDIMLG 432  

                   aWaGVpVelveypGmiHgFll<-*
                     +  +  l+ ++G++        
   mKIAA1480   433 V-NQGE-GLKFVEGVV-----    446  

COesterase: domain 1 of 1, from 47 to 652: score 725.9, E = 1.8e-214
                   *->mllllllllllllflavvataptspedpvVeTsyvgGkvrGlrvkvd
                      + +l+l l +l l+l  +++ap++    +V+T+   Gk+rG rv+  
   mKIAA1480    47    GRSLCLTLGFLSLVLRASTQAPAP----TVNTHF--GKLRGARVPLP 87   

                   g.gnkpvyaFlGIPYAkPPvGeLRFkkPqPypepWtgvldATkygpaCpQ
                    ++ +pv+++lG+PYA+PP+Ge RF +P+P p++W+g+++AT+++p+CpQ
   mKIAA1480    88 SeILGPVDQYLGVPYAAPPIGEKRFLPPEP-PPSWSGIRNATHFPPVCPQ 136  

                   .ndlgfpgFslal.hv.gsemwnkntg......ksmSEDCLYLNVytPkl
                   ++++       a+++v ++ ++ +n+    +  ++  EDCLYLNVy+P+ 
   mKIAA1480   137 nIHT-------AVpEVmLPVWFTANLDivatyiQEPNEDCLYLNVYVPTE 179  

                   asesk..........................................klP
                   + ++ +++  ++++++  ++++++ ++++++  +++++++++ ++++  P
   mKIAA1480   180 DVKRIskecarkpnkkicrkggsgakkqgedladndgdededirdsgAKP 229  

                   VmVwIHGGGFqsGsassvtlddydgpdlaasedVVVVtiNYRLGalGFLs
                   VmV+IHGG +++G++     ++ dg++la++++V+V+t+NYR+G+lGFLs
   mKIAA1480   230 VMVYIHGGSYMEGTG-----NMIDGSVLASYGNVIVITLNYRVGVLGFLS 274  

                   tgdselppppGNaGLlDQvlALrWVqeNIaaFGGDPdnVTlFGeSAGAaS
                   tgd+ ++   GN+GLlDQ++ALrWV eNIa+FGGDP ++T+FG + GA++
   mKIAA1480   275 TGDQAAK---GNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASC 321  

                   VsllllSppqsrGLFhrAIlqSGsalspwaits.pearnrakrlAkllGC
                   Vsll+lS  +s+GLF+rAI+qSGsals+wa++++p  ++++  lA ++GC
   mKIAA1480   322 VSLLTLS-HHSEGLFQRAIIQSGSALSSWAVNYqP--VKYTSLLADKVGC 368  

                   pgedseelveCLRkksaeelldaqwklllleefgffplfaFgPVvdGdtp
                   +  d  ++v+CLR+ksa+el++++   +++++   f      PV+dGd  
   mKIAA1480   369 NVLDTVDMVDCLRQKSAKELVEQDI--QPARYHVAFG-----PVIDGD-- 409  

                   daflpkdPeellkegnfnkvPlliGvtsdEGllflayvl.dp.lsadlls
                     ++p+dPe+l+++g f ++++++Gv++ EGl f+  v + ++ +    s
   mKIAA1480   410 --VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVdPEdGV----S 453  

                   eidnedlflellpellpgase.ltlklreeiadalkeeYtdd.dd.nsee
                     d+++   ++++++l+g++e++     + +++++k++Ytd+ d++n+e+
   mKIAA1480   454 GTDFDY-SVSNFVDNLYGYPEgK-----DTLRETIKFMYTDWaDRdNPET 497  

                   srdalldllsDylFvcPilrlaaaraakagapvYlYrFdyrssdsfnqyl
                    r+ l+ l++D+++v P +++ a+ +a++g+p+Y+Y F +++        
   mKIAA1480   498 RRKTLVALFTDHQWVEP-SVVTADLHARYGSPTYFYAFYHHCQ------- 539  

                   inllwppwrgvsHgdelsYvFGnpls.k.ly....steeeeklssrrmmr
                     l++p w  + Hgde++YvFG+p++++++  + ++++ + +ls +++m+
   mKIAA1480   540 -SLMKPAWSDAAHGDEVPYVFGVPMVgPtDLfpcnFSKNDVMLS-AVVMT 587  

                   ywtnFAktGnPN.............ngessglpkWppytkeeqkyylpit
                   ywtnFAktG+PN++ +++++  +++ +  ++++ W +y++ +q  yl+i+
   mKIAA1480   588 YWTNFAKTGDPNkpvpqdtkfihtkANR-FEEVAWSKYNPRDQ-LYLHIG 635  

                   llnisqk.lreldPrkvkcafw<-*
                   l++++++++r+++     +afw   
   mKIAA1480   636 LKPRVRDhYRATK-----VAFW    652  

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