hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj36325/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1477  ( 771 res)   mfj36325

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       349.6   3.4e-101   1
Pkinase_Tyr Protein tyrosine kinase                     115.2    1.2e-30   1
KA1         Kinase associated domain 1                   96.0    7.2e-25   1
UBA         UBA/TS-N domain                              31.8    1.6e-05   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase_Tyr   1/1      35   284 ..     1   272 []   115.2  1.2e-30
Pkinase       1/1      35   286 ..     1   287 []   349.6 3.4e-101
UBA           1/1     306   345 ..     1    45 []    31.8  1.6e-05
KA1           1/1     722   771 .]     1    50 []    96.0  7.2e-25

Alignments of top-scoring domains:
Pkinase_Tyr: domain 1 of 1, from 35 to 284: score 115.2, E = 1.2e-30
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtL.keigasseei
                       +l+k++G+G+F +V +++       t+ +VAVK+++k     +   
   mKIAA1477    35    YRLQKTIGKGNFAKVKLARHV----LTGREVAVKIIdKT-QLNPTS- 75   

                   eredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGd
                    +++++rE+++Mk l +HpNiV+L  v+   ++     ly+V+Ey+ gG 
   mKIAA1477    76 -LQKLFREVRTMKIL-NHPNIVKLFEVIET-EKT----LYLVMEYASGGE 118  

                   LldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLV
                     d+L +h   ++ + k+     +Qi ++ +Y ++k +vHRDL A N L+
   mKIAA1477   119 VFDYLVAH---GRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLL 165  

                   senlvVKIsDFGLaRdiynddyYvrkkgggk.l..PvkWmAPEslkygkF
                   + ++ +KI+DFG +          +++ +  ++ +     APE ++ +k+
   mKIAA1477   166 DADMNIKIADFGFSNEF-------TVGNKLDtFcgSPPYAAPELFQGKKY 208  

                   .tskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLprPen
                   +  + DVWS GV L+ +++ G  P + g    e+ e++ +  yR p  + 
   mKIAA1477   209 dGPEVDVWSLGVILYTLVS-GSLP-FDGQNLKELRERVLRGKYRIPFYM- 255  

                   CPdelYdlMlqCWaedPedRPtFselverL<-*
                    + +  +l ++    +P +R + +++  +    
   mKIAA1477   256 -STDCENLLKKLLVLNPIKRGSLEQIMKDR    284  

Pkinase: domain 1 of 1, from 35 to 286: score 349.6, E = 3.4e-101
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      y+l +++G+G+f++V++a+h+ tg++VAvKii+k   ++  ++ ++r
   mKIAA1477    35    YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFR 81   

                   rsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrlldLfdylse
                     E++ +k L+HpNIv+l++v e+++ lylV+Ey+ gG    + fdyl  
   mKIAA1477    82 --EVRTMKILNHPNIVKLFEVIETEKTLYLVMEYASGG----EVFDYLV- 124  

                   trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldengv
                     ++g++   e+ea+  ++Qi+++++Y+H++ i+HRDLK eN+Lld +++
   mKIAA1477   125 --AHGRM--KEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMN 170  

                   vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtkvD
                   +    KiaDFG++     + + +l+tf+G+p+Y+APE+ +g +++g++vD
   mKIAA1477   171 I----KIADFGFSNE--FtVGNkLDTFCGSPPYAAPELFQGKKYDGPEVD 214  

                   vWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewdsi
                   vWSlGvily l++G +PF+g+     + ++l +++l+++++++++ +   
   mKIAA1477   215 VWSLGVILYTLVSGSLPFDGQ-----NLKELRERVLRGKYRIPFYMS--- 256  

                   srsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                                ++  L+kk+L ++P kR + e+i+++ w+   
   mKIAA1477   257 ------------TDCENLLKKLLVLNPIKRGSLEQIMKDRWM    286  

UBA: domain 1 of 1, from 306 to 345: score 31.8, E = 1.6e-05
                   *->ideelvkqLreMGGGvfsreeakkALratnnnsDverAvewLleh<-
                      +d++ ++ ++ MG   f r+e+++AL    +  D+ +A+++Ll +  
   mKIAA1477   306    SDAKRIDIMVTMG---FARDEINDALVSQKY--DEVMATYILLGR   345  

                   *
                    
   mKIAA1477     -   -    

KA1: domain 1 of 1, from 722 to 771: score 96.0, E = 7.2e-25
                   *->ddksksvvkFEiqlyKlprldlyGvdfqRisGpqwlFkdLcsailne
                      d++++s+v++E++++Klprl+l+Gv+f+RisG++++Fk+++s+i+ne
   mKIAA1477   722    DARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANE 768  

                   Lkv<-*
                   Lk+   
   mKIAA1477   769 LKL    771  

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