hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbj/mbj00677/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1469  ( 663 res)   mbj00677

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
LRR_1    Leucine Rich Repeat                             87.4      3e-22  10
LRRNT    Leucine rich repeat N-terminal domain           32.3    1.1e-05   1
LRRCT    Leucine rich repeat C-terminal domain           20.6      0.037   1
fn3      Fibronectin type III domain                      7.8       0.26   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
LRRNT      1/1      44    71 ..     1    34 []    32.3  1.1e-05
LRR_1      1/10     73    97 ..     1    25 []     9.2       60
LRR_1      2/10     98   117 ..     1    25 []     8.4       81
LRR_1      3/10    119   142 ..     1    25 []     8.1       92
LRR_1      4/10    143   168 ..     1    25 []     9.3       58
LRR_1      5/10    169   188 ..     1    25 []    13.8      4.1
LRR_1      6/10    190   213 ..     1    25 []    14.4      2.7
LRR_1      7/10    214   239 ..     1    25 []     7.8    1e+02
LRR_1      8/10    240   259 ..     1    25 []    11.9       15
LRR_1      9/10    262   285 ..     1    25 []    17.0     0.45
LRR_1     10/10    286   309 ..     1    25 []    15.3      1.5
LRRCT      1/1     345   370 ..     1    26 []    20.6    0.037
fn3        1/1     420   499 ..     1    84 []     7.8     0.26

Alignments of top-scoring domains:
LRRNT: domain 1 of 1, from 44 to 71: score 32.3, E = 1.1e-05
                   *->aCpapCtCserytdglvVdCsgrgLtvavPrdlP<-*
                       Cp  C+C      +  ++C +r+Lt ++P+++P   
   mKIAA1469    44    SCPSVCRCD-----AGFIYCNDRSLT-SIPVGIP    71   

LRR_1: domain 1 of 10, from 73 to 97: score 9.2, E = 60
                   *->nLeeLdLsgCNpslsgs..lppsl.glp<-*
                        ++L+L++ N +++   ++p++l++l    
   mKIAA1469    73    DATTLYLQN-N-QIN-NvgIPSDLkNLL    97   

LRR_1: domain 2 of 10, from 98 to 117: score 8.4, E = 81
                   *->nLeeLdLsgCNpslsgslppslglp<-*
                      +++ ++L + N sl +++p   +lp   
   mKIAA1469    98    KVQRIYLYH-N-SL-DEFPT--NLP    117  

LRR_1: domain 3 of 10, from 119 to 142: score 8.1, E = 92
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                       ++eL+L+  N ++ +++  ++l++ p   
   mKIAA1469   119    YVKELHLQE-N-NI-RTITYDsLsKIP    142  

LRR_1: domain 4 of 10, from 143 to 168: score 9.3, E = 58
                   *->nLeeLdLsgCNpslsgs..lpps.l.glp<-*
                       LeeL+L++ N s+s   +++++++++     
   mKIAA1469   143    YLEELHLDD-N-SVS-AvsIEEGaFrDSN    168  

LRR_1: domain 5 of 10, from 169 to 188: score 13.8, E = 4.1
                   *->nLeeLdLsgCNpslsgslppslglp<-*
                       L+ L Ls+ N +ls ++p   glp   
   mKIAA1469   169    YLRLLFLSR-N-HLS-TIPG--GLP    188  

LRR_1: domain 6 of 10, from 190 to 213: score 14.4, E = 2.7
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                      ++eeL+L++ N ++s ++++ +l+gl+   
   mKIAA1469   190    TIEELRLDD-N-RIS-TISSPsLhGLT    213  

LRR_1: domain 7 of 10, from 214 to 239: score 7.8, E = 1e+02
                   *->nLeeLdLsgCNpslsgs..lpps.l.glp<-*
                      +L+ L L+g N  l+  ++l +  + +l    
   mKIAA1469   214    SLKRLVLDG-N-LLN-NhgLGDKvFfNLV    239  

LRR_1: domain 8 of 10, from 240 to 259: score 11.9, E = 15
                   *->nLeeLdLsgCNpslsgslppslglp<-*
                      nL+eL+L + N sl+   p   +lp   
   mKIAA1469   240    NLTELSLVR-N-SLT-AAPV--NLP    259  

LRR_1: domain 9 of 10, from 262 to 285: score 17.0, E = 0.45
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                      +L++L+L++ N +++  +pp++++ l+   
   mKIAA1469   262    SLRKLYLQD-N-HIN-RVPPNaFsYLR    285  

LRR_1: domain 10 of 10, from 286 to 309: score 15.3, E = 1.5
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                      +L  Ld+s+ N +ls  lp + +++l    
   mKIAA1469   286    QLYRLDMSN-N-NLS-NLPQGiFdDLD    309  

LRRCT: domain 1 of 1, from 345 to 370: score 20.6, E = 0.037
                   *->dlrCasPeslrGqplldlppsdfsCp<-*
                       l+C+ Pe++rG+ ++dl ++ f+C+   
   mKIAA1469   345    GLMCQAPEKVRGMAIKDLSAELFDCK    370  

fn3: domain 1 of 1, from 420 to 499: score 7.8, E = 0.26
                   *->P.saPtnltvtdvtstsltlsWspptgngpitgYevtyRqpkngge.
                      P+ +   +tv++vt++++++sW  +    p t  ++++  + ++ + 
   mKIAA1469   420    PsRKTILITVKSVTPDTIHISWRLA---LPMTALRLSW-LKLGHSPa 462  

                   ...wneltvpgtttsytltgLkPgteYevrVqAvnggGGpeS<-*
                    ++ +e +v+g  ++y +t L+P ++Y v+ +       + S   
   mKIAA1469   463 fgsITETIVTGERSEYLVTALEPESPYRVCMV---PM--ETS    499  

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