hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj00439/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1465  ( 785 res)   mfj00439

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
LRR_1    Leucine Rich Repeat                             58.4    1.5e-13   5
I-set    Immunoglobulin I-set domain                     19.9    0.00031   1
LRRCT    Leucine rich repeat C-terminal domain           19.1       0.11   1
LRRNT    Leucine rich repeat N-terminal domain           17.2       0.23   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
LRRNT      1/1      59    90 ..     1    34 []    17.2     0.23
LRR_1      1/5      92   115 ..     1    25 []    10.3       39
LRR_1      2/5     116   139 ..     1    25 []     5.6  2.3e+02
LRR_1      3/5     140   163 ..     1    25 []    18.8     0.13
LRR_1      4/5     164   187 ..     1    25 []    14.5      2.5
LRR_1      5/5     188   211 ..     1    25 []    15.8        1
LRRCT      1/1     248   271 ..     1    26 []    19.1     0.11
I-set      1/1     283   414 ..     1    97 []    19.9  0.00031

Alignments of top-scoring domains:
LRRNT: domain 1 of 1, from 59 to 90: score 17.2, E = 0.23
                   *->aCpapCtCserytdglvVdCsgrgLtvavPrdlP<-*
                      aCp pC C  +  +++  dC  + L+ +vP +lP   
   mKIAA1465    59    ACPEPCACV-DKYAHQFADCAYKELR-EVPEGLP    90   

LRR_1: domain 1 of 5, from 92 to 115: score 10.3, E = 39
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                      n+++L+Ls  N +++  l  +++ + +   
   mKIAA1465    92    NVTTLSLSA-N-KIT-VLRRGaFvNVT    115  

LRR_1: domain 2 of 5, from 116 to 139: score 5.6, E = 2.3e+02
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                      ++++L L + + ++ +++++++l +l+   
   mKIAA1465   116    QVTSLWLAH-S-EV-RTVESGaLaVLS    139  

LRR_1: domain 3 of 5, from 140 to 163: score 18.8, E = 0.13
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                      +L++LdLs+ N  +s  +p s+l++l+   
   mKIAA1465   140    QLKNLDLSH-N-LIS-NFPWSdLrNLS    163  

LRR_1: domain 4 of 5, from 164 to 187: score 14.5, E = 2.5
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                       L+ L +++ N +l gslp ++l+ lp   
   mKIAA1465   164    ALQLLKMNH-N-RL-GSLPRDaLgALP    187  

LRR_1: domain 5 of 5, from 188 to 211: score 15.8, E = 1
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                       L++L++++ N +l ++l+p++++ l+   
   mKIAA1465   188    DLRSLRINN-N-RL-RTLEPGtFdALS    211  

LRRCT: domain 1 of 1, from 248 to 271: score 19.1, E = 0.11
                   *->dlrCasPeslrGqplldlppsdfsCp<-*
                      ++ CasP++l+G p+ +lp   + C    
   mKIAA1465   248    SIACASPPELQGVPVHRLP--ALPCA    271  

I-set: domain 1 of 1, from 283 to 414: score 19.9, E = 0.00031
                   *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVsWfKd...Gqplssv
                      P+    p     + G +  + C ++G+P+P  +W    ++G  +  v
   mKIAA1465   283    PEAPGTP----LRAGLAFMLHCVAEGHPTPRLQWQLQipgGTVVL-V 324  

                   ............................................llpsdr
                   ++  +++++++++ ++++++++++ +++++ +++++ +  + ++ +p  r
   mKIAA1465   325 ppvlskeedggdkvedgegdgdedlptqteaptptpapawpappATP--R 372  

                   fkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeaeasaeLtVq<-*
                   f   ++g     +L ++      +G+YtC+A N+ G+ ++s ++tV    
   mKIAA1465   373 FLALANG-----SLLVPLLSAKEAGIYTCRAHNELGTNSTSLRVTVA    414  

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