hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mph/mph01418/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1453  ( 974 res)   mph01418

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
UCH        Ubiquitin carboxyl-terminal hydrolase        204.2      2e-57   1
Extensin_2 Extensin-like region                        -143.8       0.74   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
UCH          1/1     156   457 ..     1   273 []   204.2    2e-57
Extensin_2   1/1     448   825 ..     1   385 []  -143.8     0.74

Alignments of top-scoring domains:
UCH: domain 1 of 1, from 156 to 457: score 204.2, E = 2e-57
                RF    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   *->pgptGLvNlGNTCYmNSvLQcLfhipplrdyllsdsyeseinesnpl
                         +GL NlGNTC++NS++QcL+ +ppl++ylls ++       +++
   mKIAA1453   156    RVGAGLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEHA------RSC 196  

                RF xxxx xxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   gskg.sllcaladLfnalqsg.yksvvpsplkflqfkttlgkineefsgy
                   +  g ++lc ++  + +   ++   + p +++     + l+ki++ f  +
   mKIAA1453   197 HQGGfCMLCLMQNHMVQAFANsGNAIKPVSFI-----RDLKKIARHFRFG 241  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxxxxxx
                   mQqDAhEFllfLLdgLhedlnrvnkkpytepesdkrpdkaa.eawknhsl
                   +Q+DAhEFl++ +d++++++                   +a++  +   +
   mKIAA1453   242 NQEDAHEFLRYTIDAMQKACLN----------------GYAkLDRQ---T 272  

                RF xxxxxxxxxxxxxxxx                                  
                   rneslitdlFqGqles..................................
                     ++l++++F+G+l+s+ +++ +++ +++ ++  +   + ++  +  +  
   mKIAA1453   273 QATTLVHQIFGGYLRSrvkcsvcksvsdtydpyldialeirqaanivral 322  

                RF                             xxxxxxxxxxxxxxxxxxxxxx
                   ............................rlkisrLPpiLiihLKRFkydg
                   +   +++  ++++   + +++++ + ++r++i+r   +L++ LKRF +  
   mKIAA1453   323 elfvksdvlsgenaymcakckkkvpaskRFTIHRTSNVLTLSLKRFANF- 371  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxx  xxxxxxxxxxxxxxxxxxxxx
                   etgmnkKindkVefPleLdlssyctae..pplkYeLyaVvvHsGsslsgG
                      +  Ki + V +P++L++ +y+++++++p +Y LyaV+vHsG+s + G
   mKIAA1453   372 ---SGGKITKDVGYPEFLNIRPYMSQSsgDPVMYGLYAVLVHSGYSCHAG 418  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx   
                   HYiayikkkkknnkWykfDDekVsevseeevlersssAYiLFY<-*
                   HY++y+  k++n++Wy  +D+ V  +++  v   + +AY+LFY   
   mKIAA1453   419 HYYCYV--KASNGQWYQMNDSLVHSSNVKVV--LNQQAYVLFY    457  

Extensin_2: domain 1 of 1, from 448 to 825: score -143.8, E = 0.74
                   *->lltlvvalvslslpseasakYsYsSPPPpekpYvYkSPPpPspkyvy
                      l + + +l++l +p + +    + S    + p    S P  +p+++ 
   mKIAA1453   448    LNQQAYVLFYLRIPGSKKSPEGPVSRVGATLP----SRPKVVPEHPK 490  

                   kSPPPpkkpYvYsSPPPPs....yvykSPPPPkp...yvYkSPPpPkyvY
                   kSP       v  SP    ++++ +++  P P++ + +v +    P  + 
   mKIAA1453   491 KSPGNG----VVPSPLMAKrqdsVMMRKLPAPEEvgiPVSRNGSLPGLKL 536  

                   kSPPpPvykYkSPPPPthsppPpyvykSPPPPpkkyvykSpPpptPvYkY
                   +   +P       P P  +p P  +      P  k v+kS Pp +     
   mKIAA1453   537 QNGCAPAKTPAGSPSPRLTPTPTHMPTILDEPG-KKVKKSAPPQS---LT 582  

                   kSPPPPp....................yvYkspPpPvkk...........
                    SP   ++++++++++++++++  +++ ++  +P    +  +++++ +++
   mKIAA1453   583 TSPTTSQgspgtgesrsqrpgswasrdTIFSTSPKLLARaitnghrlkge 632  

                   ....ripyvYkSPPPPpPYvYkSpPppvkkyiyksppppephkYvYkSPP
                   +++   +   +S   P      S  p + +   +s  +   ++   + P 
   mKIAA1453   633 gsgvDLEKGDSSSSSPE--HSASSDPAKAPQTAESRAAHACDSQGTNCPT 680  

                   PPpPYvyesvpeqkikYvYkSPPPPkksYkspsppkyVYkSpPpPvipyk
                      P +      + +  + kSP   +                  P+    
   mKIAA1453   681 AGHP-KALLNGVDAKMVKLKSPALSS--------------TTTEPT---S 712  

                   YkSPPPPkkkyspaP.......rkpyvYkSPPPPtyvYkSpPpPykpptp
                     SPPP kk   +a + ++ ++       SP P  +     P        
   mKIAA1453   713 LMSPPPAKKLALSAKkastlrrATGNDIGSPSPSAFCDLTSPM----KAT 758  

                   pkiyksPPPPtPvyvYkspPpippiksssppPvyvYkSpPppvysPPPPy
                    ++  s  P +       +P+  p  s+ p+ +    S  +p     P  
   mKIAA1453   759 HPVVASTGPVSKTRTAAPAPR--P--STHPHSASLSSSSAKPLGTSEPQ- 803  

                   vYssPPPPvyvynsaPvykksPPkhhYiYsSPPPphh<-*
                               +  P    + P+    ++S   + h   
   mKIAA1453   804 ------------SCRPSAWTPLPQVNGHFTS---HLH    825  

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