hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mph/mph02187/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1445  ( 632 res)   mph02187

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
TSP1     Thrombospondin type 1 repeats                  219.3    3.4e-61   6
PSI      domain found in Plexins, Semaphorins and Int    54.1    1.8e-11   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PSI        1/1      36    83 ..     1    56 []    54.1  1.8e-11
TSP1       1/6      93   147 ..     1    66 []    -7.3       75
TSP1       2/6     148   201 ..     1    66 []    65.4  7.4e-15
TSP1       3/6     206   252 ..     1    66 []    55.4  7.4e-12
TSP1       4/6     337   389 ..     1    66 []    69.7  3.6e-16
TSP1       5/6     394   446 ..     1    66 []    59.1  5.5e-13
TSP1       6/6     449   496 ..     1    66 []    16.3     0.16

Alignments of top-scoring domains:
PSI: domain 1 of 1, from 36 to 83: score 54.1, E = 1.8e-11
                   *->rCsqygvtsCseCllardpygCgWCssegrCtrgerCderrgsrqnw
                      rCs+y   s ++Cl+ardpy CgW+  ++ C+++e+ ++++ ++qn+
   mKIAA1445    36    RCSAY--HSQGACLGARDPY-CGWDGKRQLCSTLEDSSNMSLWIQNI 79   

                   ssgpssqCp<-*
                   +     +Cp   
   mKIAA1445    80 T-----TCP    83   

TSP1: domain 1 of 6, from 93 to 147: score -7.3, E = 75
                   *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg
                       ++Ws+W pC     G  ++      R R      c+ p+p  ++gg
   mKIAA1445    93    FGPWSPWKPCE-HLDGDNSGS--CLCRAR-----SCDSPRP--RCGG 129  

                   epCs....EtrpCntqpnLqpCp<-*
                    +C +++     C+      +     
   mKIAA1445   130 LECLgpsiHIANCSR-----NGA    147  

TSP1: domain 2 of 6, from 148 to 201: score 65.4, E = 7.4e-15
                   *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg
                      w++Ws+W +CS  +CG G     +++R+R      cs+p+pr+  gg
   mKIAA1445   148    WTAWSSWAQCS-TSCGIG-----FQVRQR-----SCSNPAPRH--GG 181  

                   epCs....EtrpCntqpnLqpCp<-*
                   + C ++++E r Cn++    pCp   
   mKIAA1445   182 RICVgksrEERFCNEN---TPCP    201  

TSP1: domain 3 of 6, from 206 to 252: score 55.4, E = 7.4e-12
                   *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg
                      w +W++WS CS   CGgG     v++R+Rs    c ++      n  
   mKIAA1445   206    WASWGSWSKCS-NNCGGG-----VQSRRRS----CENG------NSC 236  

                   epCs.EtrpCntqpnLqpCp<-*
                   + C  E+++Cn++    +Cp   
   mKIAA1445   237 PGCGvEFKTCNPE----ACP    252  

TSP1: domain 4 of 6, from 337 to 389: score 69.7, E = 3.6e-16
                   *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg
                      w +W++WS+CS + C  G     +r+R+R     +c +p+p  +ngg
   mKIAA1445   337    WATWGPWSSCS-RDCELG-----FRVRKR-----TCTNPEP--RNGG 370  

                   epCs....EtrpCntqpnLqpCp<-*
                    pC ++  E+++Cn+q    +Cp   
   mKIAA1445   371 LPCVgdaaEYQDCNPQ----ACP    389  

TSP1: domain 5 of 6, from 394 to 446: score 59.1, E = 5.5e-13
                   *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg
                      ws+W+ WS+CS ++CGgG     + +RtRs    c sp+p+   +g+
   mKIAA1445   394    WSCWTAWSQCS-ASCGGG-----HYQRTRS----CTSPAPS---PGE 427  

                   epCs....EtrpCntqpnLqpCp<-*
                     C + ++E   C+tq    +Cp   
   mKIAA1445   428 DICLglhtEEALCSTQ----ACP    446  

TSP1: domain 6 of 6, from 449 to 496: score 16.3, E = 0.16
                   *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg
                      ws WseW+ C+      G      ++R+Rs    c         +g 
   mKIAA1445   449    WSLWSEWGVCT----EDG-----AQSRSRS----CEEL-----LPGP 477  

                   epCs....EtrpCntqpnLqpCp<-*
                   + C ++++++rpC  +    + p   
   mKIAA1445   478 GACVgnssQSRPCPYS----EIP    496  

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