hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg18759/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1436  ( 812 res)   mbg18759

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
ig       Immunoglobulin domain                           77.0      4e-19   4
V-set    Immunoglobulin V-set domain                     38.9    1.2e-07   2
I-set    Immunoglobulin I-set domain                    -21.2       0.63   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
ig         1/4      95   182 ..     1    65 []    22.5   0.0096
V-set      1/2      77   208 ..     1   130 []     7.4     0.11
ig         2/4     225   308 ..     1    65 []    26.2  0.00075
I-set      1/1     209   309 ..     1    97 []   -21.2     0.63
V-set      2/2     211   379 ..     1   130 []    31.6  1.8e-05
ig         3/4     355   450 ..     1    65 []    22.7   0.0085
ig         4/4     497   590 ..     1    65 []     6.2       14

Alignments of top-scoring domains:
ig: domain 1 of 4, from 95 to 182: score 22.5, E = 0.0096
                   *->GesvtLtCsvs..gfgppdvtvtWlrngk.lt.gvlvtssenngdst
                      Ge++ L+C +s++++ + +  ++W    ++++++ l+ s+e +    
   mKIAA1436    95    GEPFELRCIASttSPLHTHLALRWELHRGpVHrSILALSHEGRFHPG 141  

                   yqt...................sLtitnvtpeDggtYtCvv<-*
                   ++++++ ++++ + ++ +++  +L++ ++ + D g+Y+Cvv   
   mKIAA1436   142 PGYeqryhsgdvrldtvgsdayRLSVARALSADQGSYRCVV    182  

V-set: domain 1 of 2, from 77 to 208: score 7.4, E = 0.11
                   *->qstvtqepprLLLASLfWp.tsvtvaeGgsvtLpCtysGtfddssss
                      +++v   ++r        p++ ++  eG+  +L+C  s     ++s+
   mKIAA1436    77    ALVVGP-SSR--------PpPGLSLREGEPFELRCIAS-----TTSP 109  

                   sgtg.svyWyrqqppGekpeliiisyytyysysegngtvserfkgrvrfs
                    +t+  + W      G+ ++ i        s++ g+ ++++ +  r++ s
   mKIAA1436   110 LHTHlALRWEL--HRGPVHRSIL-----ALSHE-GRFHPGPGYEQRYH-S 150  

                   gnps.....kgdfsLtIsnlqlsDsGtYyCa..................g
                   g+ + ++ +++ + L+  ++ ++D G Y C+ ++  ++ ++  +  ++  
   mKIAA1436   151 GDVRldtvgSDAYRLSVARALSADQGSYRCVvsewiteqgswqeiqekaV 200  

                   ggtrLtVl<-*
                   +  ++++    
   mKIAA1436   201 EVATVVIQ    208  

ig: domain 2 of 4, from 225 to 308: score 26.2, E = 0.00075
                   *->GesvtLtCsvs..gfgppdvtvtWlrngk.lt.gvlvtssenngdst
                      G+++ L+C  +++   ++ ++vtW++ +++ t+   ++   + ++ +
   mKIAA1436   225    GKDLDLSCNITtdRVDDVRPEVTWYFKKTpDTsLLASHMLARLDRDS 271  

                   yqt...............sLtitnvtpeDggtYtCvv<-*
                      ++++   ++ ++++ +L +++v++e +g+Y C v   
   mKIAA1436   272 LVHssphvalshvdtrsyHLLVRDVSKENSGYYLCLV    308  

I-set: domain 1 of 1, from 209 to 309: score -21.2, E = 0.63
                   *->PkFtq..kpkdveVqeGesarfeCkVtGtPe....PtVsWfKd...G
                      P+ +q  +p+ v V+eG++++++C++t +  ++ +P+V+W+ +++++
   mKIAA1436   209    PTALQlaVPRTVSVTEGKDLDLSCNITTDRVddvrPEVTWYFKktpD 255  

                   qplssv..........l.lpsdrfkvtydgGsgtytLtIsnvqpdDsGkY
                     l + +   + ++++l  +s+++  ++++    y L +++v ++ sG Y
   mKIAA1436   256 TSLLAShmlarldrdsLvHSSPHVALSHVD-TRSYHLLVRDVSKENSGYY 304  

                   tCvAtNsaGeaeasaeLtVq<-*
                    C                V    
   mKIAA1436   305 LCL---------------VA    309  

V-set: domain 2 of 2, from 211 to 379: score 31.6, E = 1.8e-05
                   *->qstvtqepprLLLASLfWptsvtvaeGgsvtLpCtysGtfddsssss
                      ++++    pr           v+v eG+++ L+C  +   +d+  + 
   mKIAA1436   211    ALQLAV--PR----------TVSVTEGKDLDLSCNIT---TDRVDDV 242  

                   gtgsvyWyrqqppGekpeliiisyytyysysegngtvserfkgrvrfsgn
                   ++ +v+Wy+  ++  +  l + + + + +++      s +++      ++
   mKIAA1436   243 RP-EVTWYF-KKTPDTSLLAS-HMLARLDRD------SLVHSSPHVALSH 283  

                   pskgdfsLtIsnlqlsDsGtYyCa..........................
                    +  +++L  ++++ + sG Y C      ++++++ ++  +  + +++ +
   mKIAA1436   284 VDTRSYHLLVRDVSKENSGYYLCLvalwapghnrswhkvaeamsapsgvs 333  

                   .....................................gggtrLtVl<-*
                    +  +++     + ++ ++ ++++++   +  ++++ + g+rLtV+   
   mKIAA1436   334 vtwlepeyqvylnaskvpgfsddptelqcrvidtkrlEAGVRLTVS    379  

ig: domain 3 of 4, from 355 to 450: score 22.7, E = 0.0085
                   *->GesvtLtCsvs....gfgppdvtvtWlrngk.lt.gvlvt..ssenn
                       ++  L+C+v ++++ ++ +  tv+W+   ++  ++v++ +   +++
   mKIAA1436   355    DDPTELQCRVIdtkrLEAGVRLTVSWYYRMTrRNdDVVASelLAVMD 401  

                   gdstyqt.......................sLtitnvtpeDggtYtCvv<
                   gd+t +++++++++ ++++   +++++++  ++i+++t+eD g+Y+Cvv 
   mKIAA1436   402 GDWTLRYgerskqraqdgefifskehtdtfNFRIQRTTEEDRGNYYCVV  450  

                   -*
                     
   mKIAA1436     -    -    

ig: domain 4 of 4, from 497 to 590: score 6.2, E = 14
                   *->GesvtLtCsvs..gfgppdvtvtWlrngk.lt.gvlvtssenngdst
                      G+++ +tC vs+++  +p ++v  + +++    + +  +        
   mKIAA1436   497    GNTFEMTCKVSskNIKSPRYSVLITAEKPvGDlSSPNET-------K 536  

                   yqt................................sLtitnvtpeDggtY
                   y+++ ++++  + ++ ++ ++ ++   ++ ++++ + ++ +++ +D+g Y
   mKIAA1436   537 YIIsldqdsvvklenwtdasrvdgvvlekvqedefRYRMYQTQVSDAGLY 586  

                   tCvv<-*
                   +C+v   
   mKIAA1436   587 RCMV    590  

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