hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file: /cdna4/rodent/full/goal/mbp/mbp03169/w3open/interpro/cnk_1/seq.in
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Query: mKIAA1435 ( 411 res) mbp03169
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
WD40 WD40 repeats 129.2 4.4e-34 7
FYVE Protein present in Fab1, YOTB, Vac1, and EEA 91.6 9.4e-23 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
WD40 1/7 14 53 .. 1 46 [] 28.6 0.00088
WD40 2/7 57 97 .. 1 46 [] 4.5 96
WD40 3/7 104 143 .. 1 46 [] 16.8 1.1
WD40 4/7 146 184 .. 1 46 [] 0.0 4.9e+02
WD40 5/7 189 228 .. 1 46 [] 40.7 2e-07
WD40 6/7 232 271 .. 1 46 [] 27.3 0.0021
FYVE 1/1 277 354 .. 1 81 [] 91.6 9.4e-23
WD40 7/7 356 395 .. 1 46 [] 23.5 0.029
Alignments of top-scoring domains:
WD40: domain 1 of 7, from 14 to 53: score 28.6, E = 0.00088
*->t.kllrtlkgHtgespVtsvafspdggssdspnllasgs.DgtirlW
+ ll++++gH++ +Vt+ p + ++++s+D+tir+W
mKIAA1435 14 RpVLLSKIEGHQD--AVTAALLIPKE------DGVITASeDRTIRVW 52
d<-*
mKIAA1435 53 L 53
WD40: domain 2 of 7, from 57 to 97: score 4.5, E = 96
*->t.kllrtlkgHtgespVtsvafspdggssdspnllasgs.DgtirlW
+++ ++ Ht sp++++a+++d+ +++++g ++g + +
mKIAA1435 57 SgQYWPSIY-HTMASPCSAMAYHHDS------RRIFVGQdNGAVMEF 96
d<-*
+
mKIAA1435 97 H 97
WD40: domain 3 of 7, from 104 to 143: score 16.8, E = 1.1
*->t.kllrtlkgHtgespVtsvafspdggssdspnllasgs.DgtirlW
+ + ++t+++H++ +V+++ fs + ++++s ++D+++
mKIAA1435 104 KmNFIKTYPAHQN--RVSAIIFSLSA------EWVISTGhDKCVSWM 142
d<-*
mKIAA1435 143 C 143
WD40: domain 4 of 7, from 146 to 184: score 0.0, E = 4.9e+02
*->t.kllrtlkgHtgespVtsvafspdggssdspnllasgs.DgtirlW
+++ l ++ + ++++++ d ++ ++g+ g+i l
mKIAA1435 146 SgNMLGRHF-FSS--WASCLQYDLDT------QHAFVGDySGQITLL 183
d<-*
+
mKIAA1435 184 K 184
WD40: domain 5 of 7, from 189 to 228: score 40.7, E = 2e-07
*->t.kllrtlkgHtgespVtsvafspdggssdspnllasgs.DgtirlW
t +++ tlkgH+g ++ ++ ++p +ll+sg +D+++ +W
mKIAA1435 189 TcSVITTLKGHEG--SIACLWWDPIQ------RLLFSGAsDNSVIMW 227
d<-*
d
mKIAA1435 228 D 228
WD40: domain 6 of 7, from 232 to 271: score 27.3, E = 0.0021
*->t.kllrtlkgHtgespVtsvafspdggssdspnllasgs.DgtirlW
+ + l+gH + +V s+++ + ++l+s+s Dg i +W
mKIAA1435 232 RkGRTLLLQGHHD--RVQSLCYLQLT------RQLVSCSaDGGIAVW 270
d<-*
+
mKIAA1435 271 N 271
FYVE: domain 1 of 1, from 277 to 354: score 91.6, E = 9.4e-23
*->etaphWvpDeeasnClmnCgkeFtl..........vtrRrHHCRnCG
e+ap+W ++ ++C ++C+++F ++ ++ +++++ R+HHCR+CG
mKIAA1435 277 EEAPQWLES---DSC-QKCEQPFFWnikqmwdtktLGLRQHHCRKCG 319
rifCskCsskkaplpklgkekkngknedftpvRVCdsCyerlsk<-*
+ +C+kCssk++ +p +g e ++vRVCdsCy++++
mKIAA1435 320 QAVCGKCSSKRSSYPVMGFE---------FQVRVCDSCYDSIKD 354
WD40: domain 7 of 7, from 356 to 395: score 23.5, E = 0.029
*->t.kllrtlkgHtgespVtsvafspdggssdspnllasgs.DgtirlW
+++ l+t++ ++ +++++ + l++++++D+ +++W
mKIAA1435 356 DrTSLATFHEGKH--NISHMSMDIAR------GLMVTCGtDRVVKIW 394
d<-*
d
mKIAA1435 395 D 395
//