hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/Pfam Sequence file: /cdna4/rodent/full/goal/mbp/mbp03169/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA1435 ( 411 res) mbp03169 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- WD40 WD domain, G-beta repeat 114.5 2e-30 5 FYVE FYVE zinc finger 89.8 5.7e-23 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- WD40 1/5 16 53 .. 1 38 [] 25.1 0.0017 WD40 2/5 106 142 .. 1 38 [] 13.2 4.8 WD40 3/5 191 228 .. 1 38 [] 39.1 1e-07 WD40 4/5 234 271 .. 1 38 [] 23.2 0.0063 FYVE 1/1 280 354 .. 1 77 [] 89.8 5.7e-23 WD40 5/5 358 395 .. 1 38 [] 22.0 0.014 Alignments of top-scoring domains: WD40: domain 1 of 5, from 16 to 53: score 25.1, E = 0.0017 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* +l+ ++gH+++Vt+ p ++++S+D+ti++W mKIAA1435 16 VLLSKIeGHQDAVTAALLIPK-EDGVITASEDRTIRVWL 53 WD40: domain 2 of 5, from 106 to 142: score 13.2, E = 4.8 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* + ++++++H++ V+++ fs + ++++s ++D+++ W mKIAA1435 106 NFIKTYpAHQNRVSAIIFSLS-AEWVISTGHDKCVS-WM 142 WD40: domain 3 of 5, from 191 to 228: score 39.1, E = 1e-07 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* ++++l+gH++++ c+ ++p ++ll+sg +D+++ +Wd mKIAA1435 191 SVITTLkGHEGSIACLWWDPI-QRLLFSGASDNSVIMWD 228 WD40: domain 4 of 5, from 234 to 271: score 23.2, E = 0.0063 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* + l+gH + V ++++ + ++l+s+S+Dg i +W+ mKIAA1435 234 GRTLLLqGHHDRVQSLCYLQL-TRQLVSCSADGGIAVWN 271 FYVE: domain 1 of 1, from 280 to 354: score 89.8, E = 5.7e-23 *->phWvpDeevsnCmrCgkpFtk..........ltkRrHHCRaCGrifC p+W+ +++ C C++pF+++ ++ ++++l R+HHCR CG+ +C mKIAA1435 280 PQWLESDS---CQKCEQPFFWnikqmwdtktLGLRQHHCRKCGQAVC 323 gsCssktvllpylgiaallkndviekpvRVCdsCydrlnk<-* g+Cssk++++p +g e +vRVCdsCyd+ ++ mKIAA1435 324 GKCSSKRSSYPVMGF---------EFQVRVCDSCYDSIKD 354 WD40: domain 5 of 5, from 358 to 395: score 22.0, E = 0.014 *->eclavl.gHtspVtcvafspdsgpllasgSrDgtikiWd<-* + la+++ ++ ++ ++ + + l+++++ D+ +kiWd mKIAA1435 358 TSLATFhEGKHNISHMSMDIA-RGLMVTCGTDRVVKIWD 395 //