hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/smart.HMMs Sequence file: /cdna4/rodent/full/goal/mbg/mbg05674/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA1424 ( 1262 res) mbg05674 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- RhoGAP GTPase-activator protein for Rho-like GTPase 221.9 5.7e-62 1 PH Pleckstrin homology domain. 70.2 2.6e-16 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PH 1/1 243 353 .. 1 82 [] 70.2 2.6e-16 RhoGAP 1/1 470 647 .. 1 193 [] 221.9 5.7e-62 Alignments of top-scoring domains: PH: domain 1 of 1, from 243 to 353: score 70.2, E = 2.6e-16 *->vikeGwLlkks............k.swkkryfvLfngvLlyyksk.. +eGwL + ++++++ +++ + wk+ y+vL++++L++yk++++ mKIAA1424 243 AAREGWLQFRPlvtdkgkrvggsIrPWKQMYVVLRGHSLYLYKDRre 289 .....kpkgsipLsgcsvre.p.......cFeivt.drtlllqAeseeer ++++++ +i+++ c ++ + ++ +++++F+++t+d + l+qAe+ +++ mKIAA1424 290 qttpsEEEQPISVNACLIDIsYsetkrrnVFRLTTsDCECLFQAEDRDDM 339 eeWvealqsaiaka<-* +W++ +q+ ++ + mKIAA1424 340 LSWIKTIQESSNLN 353 RhoGAP: domain 1 of 1, from 470 to 647: score 221.9, E = 5.7e-62 *->spiPiivekCieylekrGldteGIYRvsGsksrvkeLreafdsged. + iP+iv+ C+ +e+rGl+ GIYRv+G++ + ++e++++g+ + mKIAA1424 470 RYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMAd 516 dldsldesiteesedleeydvhdvAglLKlyLReLPePLltfelyeefie ++ d+ ++d +++++lLK+++R+LPePL+t + y +fie mKIAA1424 517 IDIQ----------DDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIE 556 aaklyqieatsrkqseksedeeerlralrellslLPpanratLryLl.HL a + ed+ rlr l++l++ LP+++++tL++L HL mKIAA1424 557 ANRK--------------EDPLDRLRTLKRLIHDLPEHHFETLKFLSaHL 592 nrVaehsevNkMtarNLAivFgPtLlrpp.......ltdikhqnkvvetl + Vae+se+NkM +rNLAivFgPtL r ++++ ++ +t++ q k+vetl mKIAA1424 593 KTVAENSEKNKMEPRNLAIVFGPTLVRTSednmthmVTHMPDQYKIVETL 642 ienad<-* i+++d mKIAA1424 643 IQHHD 647 //