hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mph/mph00927/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1406  ( 838 res)   mph00927

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
Cullin   Cullin family                                  314.5    1.2e-90   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Cullin     1/1     337   751 ..     1   656 []   314.5  1.2e-90

Alignments of top-scoring domains:
Cullin: domain 1 of 1, from 337 to 751: score 314.5, E = 1.2e-90
                   *->WekLrdaidqiltnlknvsplsyeeLYtaVYniCtstsavphklgek
                      ++++r+++++++  ++ ++ l+ eeL++ ++++              
   mKIAA1406   337    LRRWRCHVQRFF--YRIYATLRIEELFSIIRDF-------------- 367  

                   LYnrLkeyleeyvkalrkslleisddenlLkeyikeWkdfstsmkmindi
                                                                     
   mKIAA1406     - -------------------------------------------------- -    

                   fmYLdRyyvkrnidgkkevyeiyeLgLdiWreelfdnikdrlidalLdlI
                                                                     
   mKIAA1406     - -------------------------------------------------- -    

                   ekeRkGeaidrliknvvdmlvsLgldekDmkkqklkvYkedFEkpFLeaT
                                                                     
   mKIAA1406     - -------------------------------------------------- -    

                   seFYkkEsskfLqen.svseYlkkvEkrLeeEeeRvrlYLhsstekklie
                               +++++++e lk++ +r +++++++              
   mKIAA1406   368 ------------PDSrPAIEDLKYCLERTDQRQQLLV------------- 392  

                   vvekvLIekHlefLlmehsefqLldnnkleDLrrMYrLlsRvpnGLeplr
                                                                  +l+
   mKIAA1406   393 -----------------------------------------------SLK 395  

                   kilekhvkkeGlalvskla...............................
                   + le+++ + G ++++ ++   +  +  +  +++    +   ++ ++  +
   mKIAA1406   396 VALETRLLHPGVNTCDIITlyisaikalrvldpsmvilevacepirrylr 445  

                   ..................................................
                   +++++ ++   + +++++++++   + +++++   +++++++++++++++
   mKIAA1406   446 tredtvrqivagltgdsdgtgdlavelsktdpacletgqdseddsgeped 495  

                   .....aetdpkdyVeeLLelhdkydslvneaFnnDplFlnaLdkAfesfi
                     ++++++dp                                        
   mKIAA1406   496 wvpdpVDADP---------------------------------------- 505  

                   NsnvvtkaskspELLAkYcDdlLKKgsKgleeeeleekldkiivlfkyie
                                                + ++ + ++ d+i+ l+++++
   mKIAA1406   506 -----------------------------VKSSSKRRSSDIISLLVSIYG 526  

                   dKDvFekfYrkmLAkRLLngkSasLddaEkrmiekLKqvecGyefTsKLe
                   +KD+F+++Yr++LA+RLL++ S+s  + E+r++e+LK  ++G++ ++ +e
   mKIAA1406   527 SKDLFINEYRSLLADRLLHQFSFS-PEREIRNVELLKL-RFGEAPMHFCE 574  

                   gMfkDislSkelnnsFknhlennndnldlkledeeneEgidlsvkvLstg
                   +M+kD+ +S+++n++++++ e+++ +++          ++ +++ +Ls++
   mKIAA1406   575 VMLKDMADSRRINANIREEDEKRPVEEQP---------PFGVYAVILSSE 615  

                   fWPtlp.epsinfnLPeelekalerFeefYlkkhsgpdRkLtWlhsLGkg
                   fWP++++e+   + +Pe++++al+++++ Y+k +    R L+W+h LG +
   mKIAA1406   616 FWPPFKdEK---LEVPEDIRAALDVYCKKYEKLKAM--RTLSWKHTLGLV 660  

                   elkaefndgtkskyeltVstyQmavLLLFNdkeeltyeelqeatqipede
                   ++++e+ d+t   +++ V+++Q++vLL+F+++ ++t+eel++  ++p  +
   mKIAA1406   661 TMDVELADRT---LSVAVTPVQAVVLLYFQNQASWTLEELSKVVKMPVAL 707  

                   LrrtLqsLlkakvllllllryetpgekspkdkeispntkfslNenft<-*
                   Lrr+++ +l+++vl+++ +++++    +++++ ++ ++++ ++++ +   
   mKIAA1406   708 LRRRMSVWLQQGVLREEPPGTFS---VIEEERPQDRDNMVLIDSDDE    751  

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