hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg05137/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1365  ( 1497 res)   mbg05137

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
LRR_1    Leucine Rich Repeat                            136.5    4.7e-37  15
PDZ      PDZ domain (Also known as DHR or GLGF)          73.2    5.3e-18   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
LRR_1      1/15     54    76 ..     1    25 []    13.4      5.3
LRR_1      2/15     77    99 ..     1    25 []     9.3       58
LRR_1      3/15    100   122 ..     1    25 []    13.8        4
LRR_1      4/15    123   145 ..     1    25 []     6.0    2e+02
LRR_1      5/15    146   168 ..     1    25 []     9.2       60
LRR_1      6/15    169   191 ..     1    25 []    13.2      6.2
LRR_1      7/15    192   214 ..     1    25 []    13.7      4.3
LRR_1      8/15    215   237 ..     1    25 []    15.2      1.5
LRR_1      9/15    238   260 ..     1    25 []     7.1  1.3e+02
LRR_1     10/15    261   283 ..     1    25 []    11.8       17
LRR_1     11/15    284   306 ..     1    25 []    13.9      3.8
LRR_1     12/15    307   329 ..     1    25 []     7.5  1.1e+02
LRR_1     13/15    330   352 ..     1    25 []     6.2  1.8e+02
LRR_1     14/15    353   375 ..     1    25 []     8.0       93
LRR_1     15/15    376   398 ..     1    25 []    19.5     0.08
PDZ        1/1    1408  1492 ..     1    82 []    73.2  5.3e-18

Alignments of top-scoring domains:
LRR_1: domain 1 of 15, from 54 to 76: score 13.4, E = 5.3
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      +LeeL+L+  N +++ +lp+ l +++   
   mKIAA1365    54    TLEELYLDA-N-QIE-ELPKQLfNCQ    76   

LRR_1: domain 2 of 15, from 77 to 99: score 9.3, E = 58
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                       L++L++ + N  ls slp s+ +l    
   mKIAA1365    77    ALRKLSIPD-N-DLS-SLPTSIaSLV    99   

LRR_1: domain 3 of 15, from 100 to 122: score 13.8, E = 4
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      nL+eLd+s  N  ++ ++p++++ ++   
   mKIAA1365   100    NLKELDISK-N-GVQ-EFPENIkCCK    122  

LRR_1: domain 4 of 15, from 123 to 145: score 6.0, E = 2e+02
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                       L++++ s  N ++s  lp+++  l    
   mKIAA1365   123    CLTIIEASV-N-PIS-KLPDGFtQLL    145  

LRR_1: domain 5 of 15, from 146 to 168: score 9.2, E = 60
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      nL+ L+L++    l+  lp++++ l    
   mKIAA1365   146    NLTQLYLND-A-FLE-FLPANFgRLV    168  

LRR_1: domain 6 of 15, from 169 to 191: score 13.2, E = 6.2
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      +L++L+L+  N +l ++lp+s ++l    
   mKIAA1365   169    KLRILELRE-N-HL-KTLPKSMhKLA    191  

LRR_1: domain 7 of 15, from 192 to 214: score 13.7, E = 4.3
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      +Le LdL++ N ++s +lp+ l+  +   
   mKIAA1365   192    QLERLDLGN-N-EFS-ELPEVLdQIQ    214  

LRR_1: domain 8 of 15, from 215 to 237: score 15.2, E = 1.5
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      nL+eL +++ N  l+  lp s+++l+   
   mKIAA1365   215    NLRELWMDN-N-ALQ-VLPGSIgKLK    237  

LRR_1: domain 9 of 15, from 238 to 260: score 7.1, E = 1.3e+02
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                       L +Ld+s  N +++ ++  +++g+    
   mKIAA1365   238    MLVYLDMSK-N-RIE-TVDMDIsGCE    260  

LRR_1: domain 10 of 15, from 261 to 283: score 11.8, E = 17
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                       Le L Ls+ N +l+  lp+s++ l+   
   mKIAA1365   261    ALEDLLLSS-N-MLQ-QLPDSIgLLK    283  

LRR_1: domain 11 of 15, from 284 to 306: score 13.9, E = 3.8
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      +L++L +++ N +l+  lp+ +++l+   
   mKIAA1365   284    KLTTLKVDD-N-QLT-MLPNTIgNLS    306  

LRR_1: domain 12 of 15, from 307 to 329: score 7.5, E = 1.1e+02
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                       Lee d s+ N +l+ slpp ++ l    
   mKIAA1365   307    LLEEFDCSC-N-ELE-SLPPTIgYLH    329  

LRR_1: domain 13 of 15, from 330 to 352: score 6.2, E = 1.8e+02
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      +L++L ++  N  l ++lp ++++++   
   mKIAA1365   330    SLRTLAVDE-N-FL-PELPREIgSCK    352  

LRR_1: domain 14 of 15, from 353 to 375: score 8.0, E = 93
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      n+++ +L++ N +l+  lp++++ ++   
   mKIAA1365   353    NVTVMSLRS-N-KLE-FLPEEIgQMQ    375  

LRR_1: domain 15 of 15, from 376 to 398: score 19.5, E = 0.08
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      +L++L+Ls+ N +l + lp s+ +l+   
   mKIAA1365   376    RLRVLNLSD-N-RL-KNLPFSFtKLK    398  

PDZ: domain 1 of 1, from 1408 to 1492: score 73.2, E = 5.3e-18
                   *->evtlekevkrgglGfsikggsdk..........givvsevlpGsgaA
                       v++e   k+ glGfsi+gg ++++++ +++++gi+v++v+p+ g+A
   mKIAA1365  1408    CVRIE---KNPGLGFSISGGISGqgnpfkpsdkGIFVTRVQPD-GPA 1450 

                   eagGrLkeGDqIlsvNGqdvenlsheravlalkgsggsevtLtil<-*
                        L++GD+Il+ NG +++ ++he+avl+lk+  + +v L+i+   
   mKIAA1365  1451 SNL--LQPGDKILQANGHSFVHMEHEKAVLLLKSFQN-TVDLVIQ    1492 

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