hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm11298/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1352  ( 1210 res)   mpm11298

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Anticodon_1 Anticodon-binding domain                     72.8    7.2e-18   1
tRNA-synt_1 tRNA synthetases class I (I, L, M and V)   -246.9     0.0041   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
tRNA-synt_1   1/1      51   790 ..     1   735 []  -246.9   0.0041
Anticodon_1   1/1     828   964 ..     1   176 []    72.8  7.2e-18

Alignments of top-scoring domains:
tRNA-synt_1: domain 1 of 1, from 51 to 790: score -246.9, E = 0.0041
                   *->kvlqfWeeqdyFkpsl..denkk.kekekFvildgPPYatGrlHmGH
                      + +q+We +++F+ s ++ e+ k+ +k+k+  + + PY +GrlH+GH
   mKIAA1352    51    EAQQKWEAEKVFEVSAsrLEKQKqSSKGKYFVTFPYPYMNGRLHLGH 97   

                   alnktlkDiiiRykrMqGfnVlylpGWDhhGLPiEqkVekklg.......
                    +     ++ + y+r++G+  l+++G  + G Pi + ++k  ++ +  + 
   mKIAA1352    98 TFSLSKCEFAVGYQRLKGKSCLFPFGLHCTGMPIKACADKLKReielygc 147  

                   ..........................akekkd..rkklGreeFrekcrew
                   +++ +++++++++++ ++++   +++ak+kk++   k G  +++  + + 
   mKIAA1352   148 ppdfpeeeeeeeessakpgdivvrdkAKGKKSkaAAKAGSSKYQWDIMKS 197  

                   ameyiaeirs.................qfkrLGvwvDWdreyfRTld..p
                      + + i + ++ ++  +  ++   +++k  G+ vDW r  + T+d +p
   mKIAA1352   198 LGLSDDDIVKfseaehwldyfpplavqDLKTIGLKVDWRRSFI-TTDvnP 246  

                   eyekavwwvFveLykKGLvYrgekvVnWcpaleTALsnaEVeykdkeVkd
                    y   v+w F +L ++  +  g++ + ++p+++ +  ++  + ++    +
   mKIAA1352   247 YYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGV--G 294  

                   ps..ihVafpladddlkaaflgvvdkdtsiviWTTTPWTLPaNlAlavnp
                   p + ++V+ ++ +                          +P+ l+     
   mKIAA1352   295 PQeyTLVKLKVLEP-------------------------YPSKLS----- 314  

                   dfdYvadgkdgqeylIlAtervetmlgdtgvavhltVytpidetykGseL
                          gk+    l+ At r+etm+g t+  v     +   et++G  +
   mKIAA1352   315 ----GLKGKNI--FLVAATLRPETMFGQTNCWVRPDMKYIGFETANGDIF 358  

                   egl.karhPfvdrakvveqkadaveipiiaDdyVtmefG.TGaVkiAPAH
                   +  ++a     + + +++++     +p++ +    m ++  Ga   AP  
   mKIAA1352   359 ICTqRAARNMSYQGFTKHNG----VVPVVKE---LMGEEiLGASLSAP-- 399  

                   gedDYkvGlnnikrygLevinpvdGeedGvftenAgpyqt..........
                     + Ykv       y L+++ + +  ++G+ +       t+ +++++++ 
   mKIAA1352   400 -LTCYKVV------YVLPMLTIKE--DKGTGVV------Tsvpsdspddl 434  

                   ..................................................
                      ++ ++++  +++ + +++   + ++ +  + ++ ++ +  +  ++ +
   mKIAA1352   435 aalrdlkkkqalrtkfgirddmvlpfepvpvleipgignlpavtvcdelk 484  

                   ......................y..seevpdFvGmkrfdAdkkivelLke
                    ++++++++  + +++   ++ y++  +v  F G+k+    k+i ++  e
   mKIAA1352   485 iqsqndreklaeakeklylrgfYdgVMLVDGFKGQKIQHVKKTIQKNMIE 534  

                   kGlLlkkekilhsyPfcwRsdegtpliyratpQWFVrm..delnlGrTLa
                        +  ++++ +++  Rs   +     + +QW+   +++++      +
   mKIAA1352   535 A--GDALIYMEPEKQVMSRS--ADECVVALCDQWYLDYgdENW------K 574  

                   ddalkavekgkvqwvPewgeEkrygnWleN.irDWcISRQRyWGtPIP..
                   ++  + +++   ++ +e  + k ++  l + +++   SR    Gt++P +
   mKIAA1352   575 KQTFQCLKN-METFCEE-SR-KNFEASL-DwLQEHACSRTYGLGTRLPwd 620  

                   ....lwvsedgeevvvvgsdkELpelvaarneedPGveSPielhrawvdl
                   ++  ++ + d + +       +   l+ + +           +++    l
   mKIAA1352   621 eqwlIESLSDSTIY---MAFYTVAHLLQGGDLNG--------QAES--PL 657  

                   takeslpnGkkkgtlerdeDVLD.tWFdSGswpfatlgyPfek.dglldt
                    + +++        +  + DV D ++F     pf +   P ek d+l+  
   mKIAA1352   658 GIRPQQ--------M--TKDVWDyVFFKD--APFPKTQIPKEKlDQLK-- 693  

                   eafekwfPaDmyleGsDqAvlHLlrgWFysllllgtalvgskvPyk...e
                    +fe w+P+D  + G D      +    +  +   +a+ + + + k +  
   mKIAA1352   694 QEFEFWYPVDLRASGKDL-----IPNHLSYYIYNHVAMWP-EQSDKwpvS 737  

                   vLvhGlvlDDAFYYveqGrRWVMKMSKSkGNvidPldvieGILeDLhaKl
                   v  +G+ l        + +    KMSKS GN     + ++          
   mKIAA1352   738 VRANGHLLL-------NSE----KMSKSTGNFLTLSQAVD---------- 766  

                   lggnlqpqeveKakqkkFpnGIpkyGADaLRlyLl.sssppgqdiafs<-
                                          k  AD +Rl+L++++++++ d +f   
   mKIAA1352   767 -----------------------KFSADGMRLALAdAGDTVE-DANFV   790  

                   *
                    
   mKIAA1352     -   -    

Anticodon_1: domain 1 of 1, from 828 to 964: score 72.8, E = 7.2e-18
                   *->DrWiLsrLnelikevteayenYdFnkAaralyeFiwndlcdwYlels
                      Dr + s++n+ i +++++ye+  F +A+++ +  + ++  d Y el+
   mKIAA1352   828    DRVFASEMNAGIIKTDQNYEKMMFKEALKTGFFEF-QAAKDKYRELA 873  

                   KdrlygeeeegensdadddKseapakraAqttLyevLeallrLLaPfmPF
                    + +  e                          ++++e+ ++LL Pf+P+
   mKIAA1352   874 TEGMHRE------------------------LVFRFIEVQTILLTPFCPH 899  

                   itEEiWqrLpgeeeSvhladwPvdelevdgfgevkewelidlekleaeme
                   ++E iW  L++ ++S++ a+wP ++              +d e l +  +
   mKIAA1352   900 LCEHIWTLLGK-PDSIMHASWP-VA------------GPVD-ESLIRSSQ 934  

                   llkevikaiRslRaeknikpsl.plkvliv<-*
                   +l+ev  ++R   +++ ++ + ++ +       
   mKIAA1352   935 YLMEVAHDLRLRLKNYMMPAKGkKTDKQPA    964  

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