hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mtj/mtj01524/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1347  ( 915 res)   mtj01524

Scores for sequence family classification (score includes all domains):
Model           Description                             Score    E-value  N 
--------        -----------                             -----    ------- ---
E1-E2_ATPase    E1-E2 ATPase                            346.3   3.2e-100   1
Cation_ATPase_C Cation transporting ATPase, C-terminu   190.7    2.2e-53   1
Cation_ATPase_N Cation transporter/ATPase, N-terminus    88.1    1.7e-22   1
Hydrolase       haloacid dehalogenase-like hydrolase     68.6    1.3e-16   1

Parsed for domains:
Model           Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------        ------- ----- -----    ----- -----      -----  -------
Cation_ATPase_N   1/1      20    96 ..     1    87 []    88.1  1.7e-22
E1-E2_ATPase      1/1     102   336 ..     1   245 []   346.3 3.2e-100
Hydrolase         1/1     340   661 ..     1   183 []    68.6  1.3e-16
Cation_ATPase_C   1/1     757   898 ..     1   199 []   190.7  2.2e-53

Alignments of top-scoring domains:
Cation_ATPase_N: domain 1 of 1, from 20 to 96: score 88.1, E = 1.7e-22
                   *->eelkkevdldahkltvEevleklktdpeeGLsseeaaeRlkkyGpNe
                      +    e++       v ev+  l+ d+++GL+ +e+  R++ +G+Ne
   mKIAA1347    20    SKRASELA-------VSEVAGLLQADLQNGLNKSEVSHRRAFHGWNE 59   

                   LppekktslwlkfLeQFkdplvllLlaAAiiSALdfvlgg<-*
                   +   + ++lw+k+++QFk+pl++lLla+A+iS   +++ +   
   mKIAA1347    60 FDISEDEPLWKKYISQFKNPLIMLLLASAVIS---ILMRQ    96   

E1-E2_ATPase: domain 1 of 1, from 102 to 336: score 346.3, E = 3.2e-100
                   *->villivllnatlefyqesrAekAleaLkklvpptAtVlRdGgkeeei
                       i++ ++++ t+ f+qe+r+ek+le+L klvpp+++ +R+G k+e+ 
   mKIAA1347   102    SITVAIVIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREG-KLEHT 147  

                   paeeLvpGDiVevkpGdrVPADgrvvegestLkVDESaLTGESlPVeKhs
                    a++LvpGD V +++GdrVPAD+r+ e+++ L+VDES+LTGE  P +K++
   mKIAA1347   148 LARDLVPGDTVCLSVGDRVPADLRLFEAVD-LSVDESSLTGETAPCSKVT 196  

                   dvvtp.dnp.lergnmVfaGTlvvsGsltgvVtatGddTflgkIakLVee
                    + +  + + + r n++f+GTlv+ G ++g+V++tG+++++g + k+++ 
   mKIAA1347   197 APQPAaNGDlASRSNIAFMGTLVRCGKAKGIVIGTGENSEFGEVFKMMQA 246  

                   AqssktPlQrlldkfgkiltpvililavlvfiiwllrnfnaafggswleg
                    + +ktPlQ+ +d +gk+l+  +++++ ++ ++++l+      g+++le 
   mKIAA1347   247 EEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLL------GKDILE- 289  

                   llyalifavallVaAcPegLplvvtvalalGtgrmAkkgaLVKglpAvEt
                      +++++v+l+VaA+PegLp+vvtv+lalG+ rm kk a+VK+lp vEt
   mKIAA1347   290 ---MFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVET 336  

                   <-*
                      
   mKIAA1347     -     -    

Hydrolase: domain 1 of 1, from 340 to 661: score 68.6, E = 1.3e-16
                   *->ikavvFDkDGTLtdgk...............................
                      +++++ Dk+GTLt+ + + ++  ++++ + + ++ + ++ ++   ++
   mKIAA1347   340    CNVICSDKTGTLTKNEmtvthiltsdglhaevtgvgynqfgevivdg 386  

                   eppiaeaiveaaaelgl.....lpleevekllgrgl.g.....erilleg
                     ++    +++ + +  +   + ++   + l+g++++g     + +++  
   mKIAA1347   387 DVVHGFYNPAVSRIVEAgcvcnDAVIRNNTLMGKPTeGalialAMKMGLD 436  

                   gltaell...........................................
                   gl+ +++++ + + +++ +    +  +++  ++++    ++  +   +  
   mKIAA1347   437 GLQQDYIrkaeypfsseqkwmavkcvhrtqqdrpeicfmkgayeqvikyc 486  

                   ............................................d.evlg
                   ++ ++++ +   +   ++    ++ + ++ + +     ++++ ++  +lg
   mKIAA1347   487 ttynskgqtlaltqqqrdlyqqekarmgsaglrvlalasgpelgQlTFLG 536  

                   lial.dklypgarealkaLkerGikvailTggdr.naeallealgla.lf
                   l+   d+++ g++ea+  L + G+ + ++Tg+++++a a++ +lgl +  
   mKIAA1347   537 LVGIiDPPRTGVKEAVTTLIASGVSIKMITGDSQeTAIAIASRLGLYsKT 586  

                   dvivdsddvg........g.v.gpivvgKPkpeifllalerlgvkpeevg
                   +  v++++v++ + ++ +  v+   v+ + +p+ + ++++ l+++++ v 
   mKIAA1347   587 SQSVSGEEVDtmevqhlsQiVpKVAVFYRASPRHKMKIIKSLQKNGAVV- 635  

                   pevlmvGDgvnDapalaaAGvgvamgngg<-*
                      +m GDgvnDa+al+aA++gvamg +g   
   mKIAA1347   636 ---AMTGDGVNDAVALKAADIGVAMGQTG    661  

Cation_ATPase_C: domain 1 of 1, from 757 to 898: score 190.7, E = 2.2e-53
                   *->RpPRnpkkDeliftgllffrylviGvivavatlaaFvwwfygggenG
                      +pPRn k  ++i+t  l++ +lv  +i++++tl++F+ ++ +     
   mKIAA1347   757    KPPRNWK--DSILTKNLILKILVSSIIIVCGTLFVFWRELRDNV--- 798  

                   edfgPhllygqlshwescgandltdsfkgqewCeifrkglearaqTmaFt
                                                     i     ++r++Tm+Ft
   mKIAA1347   799 ----------------------------------I-----TPRDTTMTFT 809  

                   vlVviqmfNAWEalncrsefFmhpldrnSlfqmgpgLfrNkwLllAvvls
                   ++V+++mfN   al++rs        ++S+f++g    +Nk++++Av++s
   mKIAA1347   810 CFVFFDMFN---ALSSRSQ-------TKSVFEIGL--CSNKMFCYAVLGS 847  

                   lalqllivYvPglqtiFgthpllslqeWlvvigfsflvfildElrKfikR
                   + +qll++Y+P+lq++F+t++l s++++l+++g++++v i+ E++K++ R
   mKIAA1347   848 IMGQLLVIYFPPLQKVFQTESL-SILDLLFLLGLTSSVCIVSEIIKKVER 896  

                   rr<-*
                   +r   
   mKIAA1347   897 SR    898  

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