hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj02187/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1337  ( 1243 res)   mfj02187

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
Patched  Patched family                                -372.7     0.0037   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Patched    1/1      93  1197 ..     1   941 []  -372.7   0.0037

Alignments of top-scoring domains:
Patched: domain 1 of 1, from 93 to 1197: score -372.7, E = 0.0037
                   *->llsldivytrtpsDirksytedgsrsedeplkeqkFfpgdgkpiarf
                      + ++  +  r +s    + +++   s +     +         ++++
   mKIAA1337    93    QVTNQSRARRGASR---WDYSRTYVSANTQTHAH---------WRIE 127  

                   liitakarndedytrpniLeekyLnevvqvndyiltnvslpvdgalkkie
                   li++a++         ni    +L  +  ++ +i+      + g      
   mKIAA1337   128 LIFLARGDAE-----RNIFTSERLVTIHEIERKIMD-----HPG------ 161  

                   ktfkdlC....srfCqlnepvnqhyn...gLdtKtRWGnFGPlailrsnl
                     f+++C +++  +++l +++  + ++++ L+t         ++  + + 
   mKIAA1337   162 --FREFCwkphEVLKDLPLGSYSYCSppsSLMT---------YFFPTERG 200  

                   nnvdfsridltYPtm..nffgtkiYLgpnFgGVkldpsendvekllDslt
                    +       + Y  m++++ +  ++L      ++++              
   mKIAA1337   201 GK-------IYYDGMgqDLADIRGSLELAMTHPEFYW------------- 230  

                   klklvdtksetgnlssa..klivLy......yrakfdpeeveeyske..w
                     + ++  s  +nl+s+  ++  L++ + ++y +  d+ + e+ +k++++
   mKIAA1337   231 --YVDEGLSV-DNLKSSllRSEILFgaplpnYYSV-DDRWEEQRAKFqsF 276  

                   EdsLedylenkyasdshiqvtvfSdqyledElvr..naltlvPffvvgfa
                     + +++l+++++s+  +qv +      + E++r+ n + l+ f++ +++
   mKIAA1337   277 VVTYVAMLAKQSTSK--VQVLYGGTDLFDYEVRRtfNNDMLLAFISSSCI 324  

                   iLltFsivtsvtlssrrsyalsidWvssKpiLAilGclsPlmAivtAfGl
                   + l++++ +     s              + L+  G++s +++++ A+ +
   mKIAA1337   325 AALVYILTS----CS--------------VFLSFFGIASIGLSCLVAL-F 355  

                   LF..wfGfpFnsIvc.VtPFLVLGAIGVDDmFlmvhAWqrttksrserar
                   L +  fG  +  I+++V+ F + G IGVDD+F+ ++  ++ t  ++    
   mKIAA1337   356 LYhvVFGIQYLGILNgVAAFVIVG-IGVDDVFVFINTYRQATHLED---- 400  

                   KvnvEvkkRmgevLvEaGpAItITSlTnvLsFgIGaiTptPaIqlFClyt
                        +  Rm+ ++  aG A + TSlT +++ ++  ++ +Pa+  F l+ 
   mKIAA1337   401 -----PQLRMIHTIQTAGKATFFTSLTTAAAYAANVFSQIPAVHDFGLFM 445  

                   av...AifFdFiYQiTFfaAvmaivgkremkgrhvlfvriTakavdaake
                   ++  ++++++ ++++    A++ +   + +  + ++++            
   mKIAA1337   446 SLivtCCWLAVLFTM---PAALGLWSLYMAPLESSCQNS----------- 481  

                   espkklWlkkqrlkseksakvapvekeeeknskfseveekles.......
                               ++    +k                     +s + +++ 
   mKIAA1337   482 ------------CHQKCGRK---------------------SSlhfpgdl 498  

                   .............................................ekesy
                    + +++ ++++ +++ +  +++ +  + ++++ + + ++ +  +   e  
   mKIAA1337   499 ftaperagggpaqgplpyldddipllnvedepaslelgdvslvsvHCEGL 548  

                   DssksheaeqkdavvrffleiYcpfllnpsv..rlcvllvfvvYlaiavy
                    +++++++ +         e   +++l + v++r +++++f+  l ++ +
   mKIAA1337   549 QPTPDANSRG--QLLAQLQELLHHWVLWAAVksRWVIVGLFASILILSLV 596  

                   GcvnikegLdPskLvleDSpLveilklrekevwpeGqqvqVfVNNPPdLt
                    ++++++  ++  L++ D ++  +l+l    + +eG  +     ++  L+
   mKIAA1337   597 FASRLRPASRAPLLFRPDTNIQVLLDLK-YNLSAEGISCI----TCSGLF 641  

                   ipenrdrl.nelveeFEstpyslGk.W..EnsTkFWLreYenflksSdle
                    +e  ++l+n++  ++E  +   G +W + + T           ++    
   mKIAA1337   642 -QEKPHSLqNNVRTSLEKKKRGSGVsWasRPETT---------AQE---S 678  

                   mseledeekesdddknvsvvvkdklewpsydllewflkwpgnsfWagdlv
                   ms + + +            vk k  +   ++++ +l ++   +W+    
   mKIAA1337   679 MSTVYISK------------VKSKGHP---AVYRLSLNASLPAPWQAVSP 713  

                   wdnktdkettevtkFrFttgYHgkdlsdwndRtkllke...wRgvAdeyp
                   +d    +e ++++ +r+  g       d+++   +++++ ++ ++A+   
   mKIAA1337   714 GD----GEVPSFQVYRAPFG-------DFTKKLTACMStvgLLQAASPSR 752  

                   ddFNvtVFded.......................................
                       vt   +d +++ + + +    +++++++++    ++++++ +++  
   mKIAA1337   753 K-WMVTALACDarrgwkfdfsfyvatkeqqhtrklyfaqshkppfhgrlc 801  

                   ..................................................
                     +++   ++++++++++    ++++ ++ + + + + ++  +++ +++ 
   mKIAA1337   802 vappgcllssspdgptkgffyvpsdkvpkarisatfgfnpcvntgwgkpa 851  

                   ..................................................
                    ++  +++       +  + +++++ +++  +++++   +++ +  ++ +
   mKIAA1337   852 vrplvdtgamvfvvfgiiglnrtqqmdnhvigdpgsviydssfdlfkeig 901  

                   ..................................................
                   +  +  +   ++ +  ++++ +  +++ + ++  +  +++ ++ ++++  
   mKIAA1337   902 hlcrlckaiagnlelvkpggaqclpsgysissflqmlhpeckelpepnll 951  

                   ..................................................
                   +++ +++  + ++++ +  +   ++++ +++++ ++ ++  + ++  +++
   mKIAA1337   952 pgqlshgavgvkegrvqwismafesttykgkssfqtysdylrwesflrqq 1001 

                   .....................afFlDqiltilptTiqsiiitlicMalVC
                    ++ ++++  +++ ++ ++ +  F  +i  +++++ + +++ lic+a+V+
   mKIAA1337  1002 lqtfpegsalhrgfqtcehwkQIFMEII-GVQSALYGLVLSLLICVAAVA 1050 

                   fLFIpnpitvfvitlailSIdiGVfGfLSLWGVdLDPisMitiIMSIGFS
                    +F  +++ ++ + l+il I   V+ ++ + G    ++  i++ +  G S
   mKIAA1337  1051 -VFTTHVLLLLPVLLSILGIVCLVVTIMYWSGWEMGAVEAISLSILVGSS 1099 

                   VDfsAHiaYhFyrsrgsksas...stpdeRvadALea...lGwPvfQAal
                   VD+  H   ++  +++++++ + + ++++R  ++Lea +++G  ++  al
   mKIAA1337  1100 VDYCVHLVEGYLLAGENLPPQqaeDPSSQRQWRTLEAvrhVGVAIVSSAL 1149 

                   STiLcvlvLlfVdsYMvevFa...KTvvLVvvlGllHGLifLPilLslfv
                    T+++ ++L+f    ++  Fa+ +K v L ++ ++l  L +  +lL + +
   mKIAA1337  1150 TTVIATVPLFFC---IIAPFAkfgKIVALNTGVSILYTLTVSTALLGIMA 1196 

                   t<-*
                   +   
   mKIAA1337  1197 P    1197 

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