hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbh/mbh02485/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1308  ( 924 res)   mbh02485

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RasGEF   RasGEF domain                                  372.1   5.7e-108   1
RasGEF_N Guanine nucleotide exchange factor for Ras-l   101.5    1.6e-26   1
RA       Ras association (RalGDS/AF-6) domain            82.7    7.8e-21   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
RasGEF_N   1/1     127   183 ..     1    66 []   101.5  1.6e-26
RasGEF     1/1     393   607 ..     1   227 []   372.1 5.7e-108
RA         1/1     808   895 ..     1    98 []    82.7  7.8e-21

Alignments of top-scoring domains:
RasGEF_N: domain 1 of 1, from 127 to 183: score 101.5, E = 1.6e-26
                   *->ydkvgsikggtleNiaLieyLvETRiDALtdlesedlnFvetFLltY
                      ++kv+++k+gtle  +L+e+Lv       ++++++dl++v++FL+tY
   mKIAA1308   127    TCKVRTVKAGTLE--KLVEHLV-------PAFQGSDLSYVTVFLCTY 164  

                   rsFittqelldlLikrYnl<-*
                   r+F+ttq++ldlL+krY++   
   mKIAA1308   165 RAFTTTQQVLDLLFKRYGR    183  

RasGEF: domain 1 of 1, from 393 to 607: score 372.1, E = 5.7e-108
                   *->LllDplelAkQLTLlEhelfkkItpfefLgsKmKHEGPqvWgkksfk
                      Ll++p+++A+Q+TL+++elfkk++p+++Lg        ++W+++ +k
   mKIAA1308   393    LLFPPDLVAEQFTLMDAELFKKVVPYHCLG--------SIWSQRDKK 431  

                   gkeerspnidktiknfNqltnfvsetIlkqeFPTNPEFSKkvdpkkRaev
                   gke+ +p+i++t+++fN+++n+v++t+l+++         ++++++Ra+v
   mKIAA1308   432 GKEHLAPTIRATVAQFNNVANCVITTCLGDQ---------SMKAPDRARV 472  

                   iqkfIqVAdhcReLnNFnSllaIisALysspIyRLkkTWekvppqslklI
                   ++++I+VA++cR+L+NF+Sl+aI+sAL+s++I+RLkkTWe+v+++s+++ 
   mKIAA1308   473 VEHWIEVARECRALKNFSSLYAILSALQSNAIHRLKKTWEEVSRDSFRV- 521  

                   feeLnkLmdsdrNfsnyRelLksigplappnLd...........ddfvra
                   f++L++++++++N+s +RelL+++g++++++L+ ++++ ++++++++v++
   mKIAA1308   522 FQKLSEIFSDENNYSLSRELLIKEGTSKFATLEmnprraqrrqkETGVIQ 571  

                   PCVPFfGvYLsDLtfleeGnpdyleekKINtnlvNFsKrrk<-*
                   ++VP++G++L+DL++l+++++dyl+     ++l+NF+Krrk   
   mKIAA1308   572 GTVPYLGTFLTDLVMLDTAMKDYLY-----GRLINFEKRRK    607  

RA: domain 1 of 1, from 808 to 895: score 82.7, E = 7.8e-21
                   *->dsgvlrVygedgtpgtyktilvskntTaeeViralLrKfgldaddpe
                      d++++rV ++ ++ ++yk+ilv++++ a+ Vir++++K++ld+d pe
   mKIAA1308   808    DCCIIRVSLDVDNGNMYKSILVTSQDKAPTVIRKAMDKHNLDEDEPE 854  

                   dyvLvEvslvlerggeerrvLpddEkPlqiqlqlkrdaqvrsrFlLrrre
                   dy+Lv    ++++++    ++p+++++++++         ++ F+L++r 
   mKIAA1308   855 DYELV----QIISEDHKL-KIPENANVFYAMNSTA-----NYDFILKKRT 894  

                   d<-*
                   +   
   mKIAA1308   895 F    895  

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