hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg04314/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1306  ( 1347 res)   mbg04314

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
Ank      Ankyrin repeat                                 173.7    3.1e-48   6
SAM_1    SAM domain (Sterile alpha motif)                59.4    7.6e-14   1
SAM_2    SAM domain (Sterile alpha motif)                41.6    1.8e-08   1
SH3_2    Variant SH3 domain                              18.2      0.059   1
SH3_1    SH3 domain                                       9.2      0.019   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Ank        1/6      35    67 ..     1    33 []    42.0  1.3e-08
Ank        2/6      68   100 ..     1    33 []    22.4    0.011
Ank        3/6     101   133 ..     1    33 []    36.0  8.4e-07
Ank        4/6     134   164 ..     1    33 []    15.8        1
Ank        5/6     175   207 ..     1    33 []    49.1  9.6e-11
Ank        6/6     210   239 ..     1    33 []    18.9     0.12
SH3_1      1/1     271   332 ..     1    58 []     9.2    0.019
SH3_2      1/1     272   332 ..     1    69 []    18.2    0.059
SAM_1      1/1     459   523 ..     1    66 []    59.4  7.6e-14
SAM_2      1/1     460   525 ..     1    72 []    41.6  1.8e-08

Alignments of top-scoring domains:
Ank: domain 1 of 6, from 35 to 67: score 42.0, E = 1.3e-08
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                      dGf++LH+Aal+gn+e+++lLl++ A ++++d+   
   mKIAA1306    35    DGFSALHHAALNGNTELISLLLEAQAAVDIKDN    67   

Ank: domain 2 of 6, from 68 to 100: score 22.4, E = 0.011
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                       G+ PLH+Aa  g++e +kl l++G  +n+  d   
   mKIAA1306    68    KGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSD    100  

Ank: domain 3 of 6, from 101 to 133: score 36.0, E = 8.4e-07
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                      +G  PLHlAa++g+++v ++Ll++  +++++d+   
   mKIAA1306   101    EGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDN    133  

Ank: domain 4 of 6, from 134 to 164: score 15.8, E = 1
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                       G TPL lA++ g++ vv+lLls   + +a      
   mKIAA1306   134    SGKTPLDLACEFGRVGVVQLLLS--SNMCAALL    164  

Ank: domain 5 of 6, from 175 to 207: score 49.1, E = 9.6e-11
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                      +G +PLHlAa++g++++++lLl++G d+n q++   
   mKIAA1306   175    NGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTK    207  

Ank: domain 6 of 6, from 210 to 239: score 18.9, E = 0.12
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                         T+LH Aal+g +evv+lLl+ G +  +++    
   mKIAA1306   210    ---TALHEAALCGKTEVVRLLLDSGINAQVRNT    239  

SH3_1: domain 1 of 1, from 271 to 332: score 9.2, E = 0.019
                   *->kkvvALYDYeare.sdELsFkkGDvitvleksddgWWkgrlkgtgG.
                       +v+A  DY  + +   L  k GD+itvle+++dg Wkg  +++  +
   mKIAA1306   271    LQVRATKDYCNNYdLTSLNVKAGDIITVLEQHPDGRWKGCIHDN-Rt 316  

                   ...keGliPsNYVepv<-*
                   +++++G++Ps+  e +   
   mKIAA1306   317 gndRVGYFPSSLGEAI    332  

SH3_2: domain 1 of 1, from 272 to 332: score 18.2, E = 0.059
                   *->ygraiedyvaAtdknenleeeeLslkkGdvvkvidvggskddd.gw.
                       +ra++dy + ++   +     L++k+Gd++ v+      +++++++
   mKIAA1306   272    QVRATKDYCN-NYDLTS-----LNVKAGDIITVL------EQHpDGr 306  

                   wlges....lggGrrrRGlvPssaveel<-*
                   w g  +++++g+ r+  G++Pss+ e +   
   mKIAA1306   307 WKGCIhdnrTGNDRV--GYFPSSLGEAI    332  

SAM_1: domain 1 of 1, from 459 to 523: score 59.4, E = 7.6e-14
                   *->dgwsvesVgeWLesigllgqYidnFlaagyidgdtllqlteeDLedl
                             ++ WL  igl +qY +  + +gy ++d ++ +t+eDL+++
   mKIAA1306   459    ASEGKANLAVWLSMIGL-AQYYKVLVDNGYENIDFITDITWEDLQEI 504  

                   GvtllGHrkkIlssIqgLk<-*
                   G+t+lGH+kk+++++++L    
   mKIAA1306   505 GITKLGHQKKLMLAVRKLA    523  

SAM_2: domain 1 of 1, from 460 to 525: score 41.6, E = 1.8e-08
                   *->veswslesvaeWLesiglegqYkdnFsdqgitglellllrlteedLa
                       e +++  +a WL+ igl +qY   + d+g++ ++ +   +t edL 
   mKIAA1306   460    SEGKAN--LAVWLSMIGL-AQYYKVLVDNGYENIDFI-TDITWEDL- 501  

                   klalGitsvghRkkilskiqelkqq<-*
                   + ++Git++gh+kk++ ++ +l +    
   mKIAA1306   502 Q-EIGITKLGHQKKLMLAVRKLAEL    525  

//