hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg18866/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1301  ( 1455 res)   mbg18866

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
HECTc    Domain Homologous to E6-AP Carboxyl Terminus   621.9   2.1e-182   1
WW                                                       93.9    1.9e-23   2
C2       Protein kinase C conserved region 2 (CalB)      56.3    3.8e-12   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
C2         1/1      63   174 ..     1    92 []    56.3  3.8e-12
WW         1/2     691   723 ..     1    34 []    54.0  1.9e-11
WW         2/2     869   901 ..     1    34 []    39.9  3.4e-07
HECTc      1/1    1118  1455 .]     1   407 []   621.9 2.1e-182

Alignments of top-scoring domains:
C2: domain 1 of 1, from 63 to 174: score 56.3, E = 3.8e-12
                   *->tLtvkiisArnLp.......DPYVkvs...................k
                      ++t+  ++A +L+++   ++DPY k+s +++++++ ++  ++++ ++
   mKIAA1301    63    SFTLSDLRAVGLKkgmffnpDPYLKMSiqpgkkssfptcahhgqerR 109  

                   TkvvkktlsgfNPvWnEesetFeFevpp.s.LeieVyDk.........df
                   + ++ +t    NP+W+ e  ++ F    ++ Leie++Dk  ++++  ++f
   mKIAA1301   110 STIISNTT---NPIWHRE--KYSFFALLtDvLEIEIKDKfaksrpiikRF 154  

                   iGrvtippnnahqhsadglihlsell.ggrh.kl<-*
                   +G++tip              +++ll+++  ++    
   mKIAA1301   155 LGKLTIP--------------VQRLLeRQAGdQM    174  

WW: domain 1 of 2, from 691 to 723: score 54.0, E = 1.9e-11
                   *->plPpgWeerkdpdsGrpYYyNheTketqWekPre<-*
                       lPp+We+r+d   Gr++Y++h++++t+W++P+    
   mKIAA1301   691    ALPPNWEARIDSH-GRIFYVDHVNRTTTWQRPTA    723  

WW: domain 2 of 2, from 869 to 901: score 39.9, E = 3.4e-07
                   *->plPpgWeerkdpdsGrpYYyNheTketqWekPre<-*
                       lP gWe+  d + G+ ++++h++++t++ +Pr+   
   mKIAA1301   869    ELPRGWEMKHDHQ-GKAFFVDHNSRTTTFIDPRL    901  

HECTc: domain 1 of 1, from 1118 to 1455: score 621.9, E = 2.1e-182
                   *->nsspddLkkrskeaLeIefvvnehgvgEeglDgGGvtrEFffllske
                       +s +dL++++   L+++f      vgEeglD++G++rEFffl+s+e
   mKIAA1301  1118    GYSRKDLQRNK---LYVTF------VGEEGLDYSGPSREFFFLVSRE 1155 

                   lfnptdygLFryspndnaeksktiYigrlrylLfpnPsagfaneehlaav
                   lfnp +ygLF+ys+nd+            ++    ++sa++ n+ +    
   mKIAA1301  1156 LFNP-YYGLFEYSANDT------------YTVQISPMSAFVDNHHE---- 1188 

                   yFrfiGrvlGkAlyenrllDlrFarpFyKkLLgkpkgtdvtlhDleslDP
                   +Frf Gr+lG+Al++++llD++F+rpFyK LL+      ++l+Dle+lD 
   mKIAA1301  1189 WFRFSGRILGLALIHQYLLDAFFTRPFYKALLRIL----CDLSDLEYLDE 1234 

                   elyksLvwLilvrrKleleeDlseeskslenditeveldmaLtFsivles
                   e+++sL+w+                   ++ndi ++ ld  LtF++++e 
   mKIAA1301  1235 EFHQSLQWM-------------------KDNDIHDI-LD--LTFTVNEEV 1262 

                   dfgevkvvELkpGGsnipVTeeNkkEYVhlvieyrlnkgvekqleAFreG
                    fg+ +++ELkpGG+nipVTe+NkkEY+++++ +r ++gv +q+e +++G
   mKIAA1301  1263 -FGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRG 1311 

                   FseVipeelLrylFdeeELeLLicGleeeidvddLksnTeyrggYtensq
                   F+eV++ +l + +Fd++ELeL i+G++ eid++d+++nTeyrggY++n++
   mKIAA1301  1312 FYEVVDARLVS-VFDARELELVIAGTA-EIDLNDWRNNTEYRGGYHDNHI 1359 

                   tirfkkwFWevvesFtneerrkLLqFVTGssrlPASvgGFaaLspsNGpq
                   +i   +wFW +ve+F+ne+r +LLqFVTG+s++P  ++GFa+L++sNGp+
   mKIAA1301  1360 VI---RWFWAAVERFNNEQRLRLLQFVTGTSSIP--YEGFASLRGSNGPR 1404 

                   kFtIrkagsetlsdddrLPtAhTCfNrLkLPpYsSkeiLreKLLlAIneg
                   +F+++k+g     + + LP+AhTCfNrL+LPpY S ++L+eKLL+A++e 
   mKIAA1301  1405 RFCVEKWG-----KITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEE- 1448 

                   RiggeGFgls<-*
                      +  Fgl+   
   mKIAA1301  1449 ---TSTFGLE    1455 

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