hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg18866/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1301  ( 1455 res)   mbg18866

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
HECT     HECT-domain (ubiquitin-transferase)            574.7     6e-169   1
WW       WW domain                                      101.1    2.1e-26   2
C2       C2 domain                                       44.5    2.3e-09   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
C2         1/1      64   159 ..     1    88 []    44.5  2.3e-09
WW         1/2     692   721 ..     1    30 []    58.0  2.1e-13
WW         2/2     870   899 ..     1    30 []    43.6  4.6e-09
HECT       1/1    1150  1455 .]     1   366 []   574.7   6e-169

Alignments of top-scoring domains:
C2: domain 1 of 1, from 64 to 159: score 44.5, E = 2.3e-09
                   *->LrVtvieAknLppkDfkngksDPYVkvslggdkkdqk..........
                       ++  ++A +L++   ++  +DPY k+s+ + kk +  ++  +++++
   mKIAA1301    64    FTLSDLRAVGLKK-G-MFFNPDPYLKMSIQPGKK-SSfptcahhgqe 107  

                   kkTkvikktlNPvWN.EtFtFevpppdlqetLeieVyDydrfgr...ddf
                   +++ +i +t NP+W++E++ F       ++ Leie++D+  ++r+   +f
   mKIAA1301   108 RRSTIISNTTNPIWHrEKYSFF--ALLTDV-LEIEIKDKFAKSRpiiKRF 154  

                   lGevs<-*
                   lG+ +   
   mKIAA1301   155 LGKLT    159  

WW: domain 1 of 2, from 692 to 721: score 58.0, E = 2.1e-13
                   *->LppgWeerkdpdGrpYYyNhnTktTqWekP<-*
                      Lpp+We+r+d++Gr++Y++h+++tT+W++P   
   mKIAA1301   692    LPPNWEARIDSHGRIFYVDHVNRTTTWQRP    721  

WW: domain 2 of 2, from 870 to 899: score 43.6, E = 4.6e-09
                   *->LppgWeerkdpdGrpYYyNhnTktTqWekP<-*
                      Lp gWe+  d +G+ ++++hn++tT++++P   
   mKIAA1301   870    LPRGWEMKHDHQGKAFFVDHNSRTTTFIDP    899  

HECT: domain 1 of 1, from 1150 to 1455: score 574.7, E = 6e-169
                   *->tLlsrelfnPdygLFeysdnseakseeddsysgyvedsytlfpnPls
                      +L+srelfnP+ygLFeys                ++d+yt +++P s
   mKIAA1301  1150    FLVSRELFNPYYGLFEYS----------------ANDTYTVQISPMS 1180 

                   gesnpehervlkyFkflGrilGlAlydgrllDlpFsraFyKklLmagkps
                    +  ++h   +++F+f GrilGlAl ++ llD++F+r+FyK lL  +   
   mKIAA1301  1181 AF-VDNH---HEWFRFSGRILGLALIHQYLLDAFFTRPFYKALL--RIL- 1223 

                   igivtleDlesvDPelynSLkwllendgdKkIedsLLgsledveedLeLt
                      ++l+Dle +D e+++SL+w+++nd+                ++L+Lt
   mKIAA1301  1224 ---CDLSDLEYLDEEFHQSLQWMKDNDIH---------------DILDLT 1255 

                   FsveeessvgfeadarffGgtktveELkPnGrnipVTneNkeeYvelyvd
                   F+v ee+   f       G+++++e LkP+G+nipVT++Nk+eY+e++v 
   mKIAA1301  1256 FTVNEEV---F-------GQITERE-LKPGGANIPVTEKNKKEYIERMVK 1294 

                   yrLnkgiekQfeAFrkGFsevipsrlLslFdpeELelLicGspeeiDvdd
                   +r  +g+ +Q+e++ +GF+ev++ rl+s+Fd++ELel+i G   eiD++d
   mKIAA1301  1295 WRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTA-EIDLND 1343 

                   LkenTeYdggYtedsplktiqwFWevleeftneeraklLqFvTGssRlPv
                   +++nTeY+ggY+++++  +i+wFW ++e f+ne+r +lLqFvTG+s++P 
   mKIAA1301  1344 WRNNTEYRGGYHDNHI--VIRWFWAAVERFNNEQRLRLLQFVTGTSSIPY 1391 

                   gGFkaLqgGsnGpPkFtIvrkegggdddrLPtAhTCFNrLkLPpYsSkei
                   +GF++L+ GsnGp++F+++++   g+ + LP+AhTCFNrL+LPpY+S   
   mKIAA1301  1392 EGFASLR-GSNGPRRFCVEKW---GKITALPRAHTCFNRLDLPPYPSFSM 1437 

                   LrekLllAInEgseGFgle<-*
                   L+ekLl+A+ E++  Fgle   
   mKIAA1301  1438 LYEKLLTAV-EETSTFGLE    1455 

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