hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj02180/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1258  ( 487 res)   mfj02180

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N 
--------     -----------                                -----    ------- ---
Amidohydro_1 Amidohydrolase family                      228.7    8.4e-65   1
Amidohydro_3 Amidohydrolase family                      -95.9       0.81   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
Amidohydro_3   1/1     106   432 ..     1   533 []   -95.9     0.81
Amidohydro_1   1/1     106   434 ..     1   479 []   228.7  8.4e-65

Alignments of top-scoring domains:
Amidohydro_3: domain 1 of 1, from 106 to 432: score -95.9, E = 0.81
                   *->lVlPGFvDsHtHldggglnlrwldlsgvgvtsvaaalallrdraara
                      + +PG+vD H+H                                   
   mKIAA1258   106    FFMPGLVDTHIH----------------------------------- 117  

                   kpkgdWvvGhgwdeaqwaerrlpetradlvwdaasppdnPvllhrvcghl
                                   ++ +  + +  dl    ++               
   mKIAA1258   118 ----------------APQYAFAGSNVDL---PLLE-------------- 134  

                   avlnsarnaLelaGItkdtpdPpGGiivrdadgnptGlLrenaqvldlvl
                    +ln+                                         ++++
   mKIAA1258   135 -WLNKY-----T----------------------------------FPTE 144  

                   gaapatladlaelaralrayaikelnalGittghdganvtSldDpvpgfe
                    ++ +t ++++ + r +r+       ++G tt+   +             
   mKIAA1258   145 QRFRSTDVAEEVYTRVVRR-----TLKNGTTTACYFG------------T 177  

                   agpaellaalralaaegkLpvrvhlhl.............ehadferlka
                   + ++  l  ++  ++ g+  +   ++++ +++ ++ ++++e+++ e  ++
   mKIAA1258   178 IHTDSSLILAEITDKFGQRAFVGKVCMdlndtvpeykettEESVKETERF 227  

                   sgel.gagddllriGgvkifvdGapgegrtallsepdyadepgpeidisg
                     e  + ++ +++    ++f ++    + ++l+se +  +++    +   
   mKIAA1258   228 VSEMlQKNYPRVKPIVTPRFTLS----CTETLMSELGNIAKT----H--- 266  

                   vpifddeerelceelvaaahaaGlqvavhAyvyggtswltfesgdaaida
                        d    +   ++ + ++      + A          + s  ++  +
   mKIAA1258   267 -----DLY--I-QSHISENREE-----IEA----------VKSLYPSYKN 293  

                   vlnayeavladlGppkrgrRhrlihaevattdqidraaelglsadvqpkw
                   ++++y++ +    + k+ + h++  +e   +   +r a + +++    + 
   mKIAA1258   294 YTDVYDKNNLL--TNKTVMAHGCYLSEEELNIFSERGASIAHCPNSNLSL 341  

                   snldhflaydggvvpflywvrsrlgperarlsypiklllnaGPfvvkval
                   s                            ++++ + + l+     vk++l
   mKIAA1258   342 S----------------------------SGLLNVLEVLKHK---VKIGL 360  

                   GsDaPvggpatldPwSlgigaavtrrtaeelegrvlkpdrdgsslggidg
                   G+D  v+g  ++  +  +i  av+  ++  +     + +           
   mKIAA1258   361 GTD--VAGGYSYSML-DAIRRAVMVSNVLLIN---KVNE----------- 393  

                   iCayTfLhwRRerlsleeAlalyTrgpAyalgledrkGtLevGkdADlvi
                              + l+l e ++l T+g+ +algl+ + G  evGk  D  +
   mKIAA1258   394 -----------KNLTLKEVFRLATLGGSQALGLDSEIGNFEVGKEFDALL 432  

                   <-*
                      
   mKIAA1258     -     -    

Amidohydro_1: domain 1 of 1, from 106 to 434: score 228.7, E = 8.4e-65
                   *->ivlPGlIPdDaHvHlrqsllrGgsaddlpLldWLnkliwpleaelvs
                      + +PGl+  D+H+H++q ++  gs+ dlpLl+WLnk+++p+e +++s
   mKIAA1258   106    FFMPGLV--DTHIHAPQYAFA-GSNVDLPLLEWLNKYTFPTEQRFRS 149  

                   eedsyealllgaeemlrsGtTtvldtpvtrantdgkgvplmleeaktplq
                    + ++e++ + ++++l+ GtTt++ +++ +++                  
   mKIAA1258   150 TDVAEEVYTRVVRRTLKNGTTTACYFGTIHTD------------------ 181  

                   fyfllpscvpareeideglaaapkleplmslllkgevggraelgevvidr
                                  + ++ a+++          +  g+ra +g+v++d 
   mKIAA1258   182 ---------------SSLILAEIT----------DKFGQRAFVGKVCMDL 206  

                   aageavfvfpDGMaigvasdevrkavrevlkegadlikkiadaakgakai
                   +             + v  +e + +++e+ ke++++++++    + +   
   mKIAA1258   207 N-------------DTV--PEYKETTEESVKETERFVSEMLQK-NYP--- 237  

                   dgvlpalaphdpptvsheelkaavelaeeteeaeklgllvhiHaaeasge
                    +v p+++p++  +++++++++  ++a+      + +l++  H++e+++e
   mKIAA1258   238 -RVKPIVTPRFTLSCTETLMSELGNIAKT-----H-DLYIQSHISENREE 280  

                   IFDREeFikLpLkFPhLkevvehlttkgmspverlakkagvviianvats
                                    +e+v+ l+                       +s
   mKIAA1258   281 -----------------IEAVKSLY-----------------------PS 290  

                   ttdhlgll.knaikggvdllaHclhLdkrededvalQellkernqLveaa
                     +++  ++kn++   +++ aH+ +L+   +e  +l  +++er       
   mKIAA1258   291 YKNYTDVYdKNNLLTNKTVMAHGCYLS---EE--EL-NIFSER------- 327  

                   gsgvahcplsnesvphdggkksllegdagmgelgsgiarlaelaekagvn
                   g+++ahcp sn s                   l+sg++++ e+++  +v+
   mKIAA1258   328 GASIAHCPNSNLS-------------------LSSGLLNVLEVLKH-KVK 357  

                   rGpVglGTDtdaGansnnsldlleemka..flllggpkfygldpnllspi
                      +glGTD+ +G +  ++ +++++ ++++ ll++  k+++ +   l+++
   mKIAA1258   358 ---IGLGTDVAGGYSYSMLDAIRRAVMVsnVLLIN--KVNEKN---LTLK 399  

                   ealrmaTinpAkalGlddkvGsievGkdADlvvvd<-*
                   e++r aT++++ alGld ++G +evGk+ D  +++   
   mKIAA1258   400 EVFRLATLGGSQALGLDSEIGNFEVGKEFDALLIN    434  

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