hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbf/mbf02919/w3open/interpro/cnk_1/seq.in
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  mKIAA1253  ( 461 res)   mbf02919

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
TMS_TDE     TMS membrane protein/tumour differentiall  1054.9          0   1
Bac_Ubq_Cox Bacterial Cytochrome Ubiquinol Oxidase     -320.0       0.44   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Bac_Ubq_Cox   1/1      98   424 ..     1   576 []  -320.0     0.44
TMS_TDE       1/1      23   460 ..     1   485 []  1054.9        0

Alignments of top-scoring domains:
Bac_Ubq_Cox: domain 1 of 1, from 98 to 424: score -320.0, E = 0.44
                   *->LsRlQFAlTalfHflFvpLTlGLallLaimetlYvktgdeeRhivYa
                        Rl F+l + +             lL+ ++ + vk+  +    + a
   mKIAA1253    98    VYRLCFGLAMFY-------------LLLSLLMIKVKSSSD---PRAA 128  

                   dmakFWgklFaINFAlGVvTGivmeFQFGtNWsgySeyVGdifGAPLAiE
                    +  FW                         +  ++++V+ i+GA +  E
   mKIAA1253   129 VHNGFW-------------------------FFKFATAVAIIIGAFFIPE 153  

                   almAFFLEstFlGlflFGwDRlspkihilatwlVaiGanLSafWILvANs
                   ++        F  ++++    ++ +  ++ +   ++      ++I  A+s
   mKIAA1253   154 GT--------FTTVWFY----VGMAGAFCFILIQLV------LLIDFAHS 185  

                   WmQtPaGaGPiAKSiYPFmPEFGGLAADAQKLViLKeFnienGreiQAii
                   W    +                               ++  n r      
   mKIAA1253   186 WNESWVE-----------------------------KMEEGNSR------ 200  

                   QNPEVAGKVGaeltDflaaifNPsapvkfvHmvfAafvTGAffVagiSAy
                                  ++aa++   a + ++     ++v++++f      +
   mKIAA1253   201 --------------CWYAALLSATALNYLL-----SLVAVVLF------F 225  

                   ylLkgRKKrdvdfakrSlklAlvigliaallqillGDesGyevaevQPaK
                    +++    +   + ++++ +++ ++l+ + ++  +       + e+QP  
   mKIAA1253   226 VYYTH---PASCAENKAF-ISVNMLLCIGASVMSI----LPKIQESQPR- 266  

                   LAAMEalWETtspaPaaltlfadPnelivGFdeferekNsfgaieIPylL
                        +l + +s        +++  +      + e e+N +     P lL
   mKIAA1253   267 ----SGLLQ-SSVITVYTMYLTWSAM------TNEPETNCN-----PSLL 300  

                   SiLAthmsfdlaTapViGLKdlpaeeekrirkGlraydLLeeLrakepev
                   Si++ +   +  T p++  Kd++ +                         
   mKIAA1253   301 SIIGFN---T--TRPIP--KDGQSV------------------------- 318  

                   kaqFngvkkDLGYGLLLkrYtpnvvdateeQilaalkdaiPpvavvFwSF
                                                           + +  +    
   mKIAA1253   319 --------------------------------------QWWHPQGI---- 326  

                   RiMVglGfllillaligfwltlRllkkieqskwLLrlalla..lPlGVFL
                        +G++l+ll +  f+  +R     ++   + +l+l+++++ l    
   mKIAA1253   327 -----IGLVLFLLCV--FYSSIR----TSNNSQVNKLTLTSdeSTL---- 361  

                   GpliAieaGWivaEvGRQPWvvygiLkTaeavSsnLttGqllfsli....
                        ie G      GR             +   +L  G+ +  ++++++
   mKIAA1253   362 -----IEDG-----NGR-------------SDG-SLDDGDGIHRAVdner 387  

                   .....lfvvlYaallaaelylmirlaRkGPsalklgrypf<-*
                   ++ +   +++ + l++a ly m+ l    ++  + + ++    
   mKIAA1253   388 dgvtySYSFFHFMLFLASLYIMMTLTN-WYR--YEPSREM    424  

TMS_TDE: domain 1 of 1, from 23 to 460: score 1054.9, E = 0
                   *->ACCcGsaaCaLcCrtcPSgknSrsGTRlmYAllLllgtivswVmlsP
                      +C+cGsa+C L+Cr+cPSg+nS++ TRl+YAl+Ll+g++v++Vml+P
   mKIAA1253    23    PCLCGSAPC-LLCRCCPSGNNSTV-TRLIYALFLLVGVCVACVMLIP 67   

                   gvqkqleklpwfCegftklekyGALsAvsGGsagvpCeelvGYkAVYRVC
                   g+++ql+k+p+fCe    +ek           ++vpC++lvGYkAVYR+C
   mKIAA1253    68 GMEEQLNKIPGFCE----NEK-----------GVVPCNILVGYKAVYRLC 102  

                   fGlAcFFllLsLlmiGVKSskDpRaaIhNGFWffKflllfaliigaFFIP
                   fGlA+F+llLsLlmi+VKSs+DpRaa+hNGFWffKf++++a+iigaFFIP
   mKIAA1253   103 FGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFATAVAIIIGAFFIP 152  

                   nqetfitvwmyVGmvGaffFILvQLvLlVDFAHgWaEtWvekvEseDEnS
                   + +tf+tvw+yVGm+Gaf+FIL+QLvLl+DFAH+W+E+Wvek+E++  nS
   mKIAA1253   153 E-GTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEG--NS 199  

                   rfWYaaLlvvTllmYlaslvalvllfvyfThsGddCglNkffiivnlilc
                   r+WYaaLl++T+l+Yl+slva+vl+fvy+Th+ ++C++Nk+fi+vn++lc
   mKIAA1253   200 RCWYAALLSATALNYLLSLVAVVLFFVYYTHP-ASCAENKAFISVNMLLC 248  

                   vaiSvlSisPkVQErnPrSGLLQsSvISvYctYLTwSAlaSePdekeCNP
                   +++Sv+Si+Pk+QE++PrSGLLQsSvI+vY++YLTwSA+++eP e++CNP
   mKIAA1253   249 IGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEP-ETNCNP 297  

                   GmFellsnvtkavstgLGSLFTFiAiAavtkddafrsafqvtntiGLlll
                      +lls++++++++            +++kd++++++++++++iGL+l+
   mKIAA1253   298 ---SLLSIIGFNTTR------------PIPKDGQSVQWWHPQGIIGLVLF 332  

                   llCivYssirassrtqlrkltdksdneEkellesalsdtedgtDseegkk
                   llC++Yssir+s+++q++klt  ++++E++l+e++++++++++D+++g++
   mKIAA1253   333 LLCVFYSSIRTSNNSQVNKLT--LTSDESTLIEDGNGRSDGSLDDGDGIH 380  

                   eeeGPRvvDdEkkGVtYSYSfFHfiFfLASLYvMMtLTsWytyddssiel
                   ++     vD+E++GVtYSYSfFHf++fLASLY+MMtLT+Wy+y+ +s+e+
   mKIAA1253   381 RA-----VDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYE-PSREM 424  

                   fnvrnwasvWVKivSSWicvgLYgWTLVAPiilPdReF<-*
                   ++  +w++vWVKi+SSWi+++LY+WTLVAP++l++R+F   
   mKIAA1253   425 KS--QWTAVWVKISSSWIGLVLYVWTLVAPLVLTNRDF    460  

//