hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file: /cdna4/rodent/full/goal/meh/meh00539/w3open/interpro/cnk_1/seq.in
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Query: mKIAA1251 ( 1900 res) meh00539
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
SPEC Spectrin repeats 193.0 2.8e-53 10
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
SPEC 1/10 233 330 .. 1 104 [] 45.4 7.5e-09
SPEC 2/10 333 433 .. 1 104 [] 29.2 0.00058
SPEC 3/10 810 921 .. 1 104 [] -6.2 31
SPEC 4/10 928 1057 .. 1 104 [] 3.5 4.1
SPEC 5/10 1075 1183 .. 1 104 [] 40.7 1.9e-07
SPEC 6/10 1200 1308 .. 1 104 [] 25.6 0.0067
SPEC 7/10 1353 1461 .. 1 104 [] -0.5 9.7
SPEC 8/10 1468 1578 .. 1 104 [] 45.4 7.3e-09
SPEC 9/10 1585 1691 .. 1 104 [] 46.7 3e-09
SPEC 10/10 1698 1800 .. 1 104 [] 25.1 0.01
Alignments of top-scoring domains:
SPEC: domain 1 of 10, from 233 to 330: score 45.4, E = 7.5e-09
*->qqFlrdadeleaWleekeqllssedlgeskDlesveallkkHqalea
+ lr + el++W+ee++ l+ ++g +Dl+sve +l+ +q + +
mKIAA1251 233 EGNLRFVYELLSWVEEMQMKLERAEWG--NDLPSVELQLETQQHIHT 277
elaaheervdalnelgeqLieesghpdaeeIeerleeLnerWeeLlelae
+++ + +v++ ++ ++ ++ ++e l +L++++ +L+e +
mKIAA1251 278 SVEELGSSVKEARLYEGKMSQN---FHTSYVET-LGKLETQYCKLKETSS 323
eRrqkLe<-*
R ++L+
mKIAA1251 324 FRMRHLQ 330
SPEC: domain 2 of 10, from 333 to 433: score 29.2, E = 0.00058
*->qqFlrdadeleaWleekeqllssedlgeskDlesveallkkHqalea
++F + a ++ Wl+ ke+ d+ ++ +++ a+ + +l
mKIAA1251 333 HKFVSRATAELIWLNGKEEEELACDWS--DSNPNISAKKTYFSELTM 377
elaaheervdalnelgeqLieesghpdaeeIeerleeLnerWeeLlelae
el+ +++ + l++++e L e +hp+++++e+ ++++++ + ++l+
mKIAA1251 378 ELEGKQDVFRFLQDTAEVLSLE-NHPAKQTVEAYSAAVQSQLQWMKQLCL 426
eRrqkLe<-*
+q+ +
mKIAA1251 427 CVEQHVK 433
SPEC: domain 3 of 10, from 810 to 921: score -6.2, E = 31
*->qqFlrdadeleaWleeke.qllssedlgeskDlesveallk......
r ++++e ++ e +l + e ++ Dl+++e+ + ++
mKIAA1251 810 DVIVRSMQDAELLVKGYEiKLSQEEAVP--ADLSALESHRTtlqhwl 854
.kHqaleaelaaheervdalnelgeqLiee..sghpdaeeIeerleeLne
+ ++ + e++ + ++ +eqL ++ + d e +e+ +L+e
mKIAA1251 855 sDVKDKNSVFSVLDEEITKAKKVAEQLRHPasEPNLDLERYQEKGSQLQE 904
rWeeLlelaeeRrqkLe<-*
rW+++ +++e R+ e
mKIAA1251 905 RWHRVIAQLETRQSEVE 921
SPEC: domain 4 of 10, from 928 to 1057: score 3.5, E = 4.1
*->qqFlrdadeleaWleekeqllssedlgeskDlesveallkkHqalea
+ + + l++W+ee+ ++ + + +g + D + ++l ++ +l a
mKIAA1251 928 RDYRACHGTLIKWIEETTAQQEMMKPGQAEDSRVLSEQLSQQTELFA 974
elaaheervdalnelgeqLieesghpdaeeIeerl...............
e++ ++ ++d++++ +q ++++ + + ++++++++++++
mKIAA1251 975 EIERNQTKLDQCQKFSQQYSTIVKDYELQLMTYKAfvesqqkspgkrrrm 1024
...........eeLnerWeeLlelaeeRrqkLe<-*
++++ +++ +L++r+ +L l+ + +
mKIAA1251 1025 isssdaitqefMDLRTRYTALVTLTTQHVKYIS 1057
SPEC: domain 5 of 10, from 1075 to 1183: score 40.7, E = 1.9e-07
*->qqFlrdadeleaWleeke..qllssedlgeskDlesveallkkHqal
q+ +++++l+ W++ ++++ +++ +++e+ + ++q l
mKIAA1251 1075 QEHVEKVKDLLGWVSTLArnTQGTTTSSH-TSASADIEKAILEQQVL 1120
eaelaaheervdalnelgeqLiee....sghpdaeeIeerleeLnerWee
+el++++e+v++ +++ + ++++++++ ++ ++e+I e+l+ Ln+ +++
mKIAA1251 1121 AEELTTKKEQVSEAIKTSQIFLAKhghkLSEGEKEQISEQLRVLNKTYHD 1170
LlelaeeRrqkLe<-*
L++ ++++ q+L+
mKIAA1251 1171 LCDGSANQLQQLQ 1183
SPEC: domain 6 of 10, from 1200 to 1308: score 25.6, E = 0.0067
*->qqFlrdadeleaWleekeqllssedlgeskDlesveallk...kHqa
++++++l +W++ +e++l+ g + +++ al+++++ +++
mKIAA1251 1200 DTCHKKLEDLCNWVGQAERALERHQGG--ASRQELPALQQnqsDLKD 1244
leaelaaheervdalnelgeqLiee....sghpdaeeIeerleeLnerWe
l+ +++ h ++ + + e ++ee++++ ++ + +++e+l++ +e++e
mKIAA1251 1245 LQGDIQSHSTSFATAVKDIEGFLEEnqtkLSPQELTALREKLHQAKEQYE 1294
eLlelaeeRrqkLe<-*
L+e+++ ++ Le
mKIAA1251 1295 VLQERTRVAQKELE 1308
SPEC: domain 7 of 10, from 1353 to 1461: score -0.5, E = 9.7
*->qqFlrdadeleaWleekeqllssedlgeskDlesveallk....kHq
q l ++++ ek++l++++ + D+ +v + l+++ + +
mKIAA1251 1353 QASLPGMEQFSGACLEKQTLAATDGH---VDVNQVPETLDrqyeLMK 1396
aleaelaaheervdalnelgeqLiee....sghpdaeeIeerleeLnerW
a +el +++ + ++ ++ ++++++++ +++ ++++e+l eL+e++
mKIAA1251 1397 ARHQELLSQQQNFIVATQSAQSFLDQhshnLTPEERQKLQEKLGELKEQY 1446
eeLlelaeeRrqkLe<-*
++ l+++e+ ++ +
mKIAA1251 1447 AASLARSEAELKQTQ 1461
SPEC: domain 8 of 10, from 1468 to 1578: score 45.4, E = 7.3e-09
*->qqFlrdadeleaWleekeqllssedlgeskDlesveallkkHqalea
q+Fl+d +e+e+Wl+ e l s+ g ++e++++llk++ + +
mKIAA1251 1468 QKFLQDHKEFENWLQQSENELDSMHKG-GSSPEALNSLLKRQGSFSE 1513
elaaheervdalnelgeqLiee........sghpdaeeIeerleeLnerW
++ h+ + ++ g++ +e +++ +++++ + + e+l++ er+
mKIAA1251 1514 DVISHKGDLRFVTISGQKVLETennfeegqEPSATRNLVNEKLKDATERY 1563
eeLlelaeeRrqkLe<-*
L+ ++ + + +L
mKIAA1251 1564 TTLHSKCIRLGSHLS 1578
SPEC: domain 9 of 10, from 1585 to 1691: score 46.7, E = 3e-09
*->qqFlrdadeleaWleeke...qllssedlgeskDlesveallkkHqa
qqF++ ad l aW+ e + l s+ ++ D+ ++++l ++
mKIAA1251 1585 QQFQSSADSLQAWVLTCEasvGKLLSDTVA--SDPGVLQQQLATTKQ 1629
leaelaaheervdalnelgeqLiee..sghpdaeeIeerleeLnerWeeL
l++ela+h+ v++l++++ +L++ +++ d I+e + + +r+++L
mKIAA1251 1630 LQEELAEHQVPVEKLQKAAHDLLDIegEPALDCRPIQETTDSISSRFQNL 1679
lelaeeRrqkLe<-*
++eR + L+
mKIAA1251 1680 SCSLDERSALLQ 1691
SPEC: domain 10 of 10, from 1698 to 1800: score 25.1, E = 0.01
*->qqFlrdadeleaWleekeqllssedlgeskDlesveallkkHqalea
q ++ ++ l++ ++e eq l+ + ++ s + +++ l l++
mKIAA1251 1698 QSVQESMESLLQSIREVEQNLERDQVA-SLSSGVIQEALANNMKLKQ 1743
elaaheervdalnelgeqLieesghpdaeeIeerleeLnerWeeLlelae
++a ++ +++a +++ +++e + a ++ +l+eL +r+++L+ + +
mKIAA1251 1744 DIARQKSSLEATHDMVTRFMETADSNSASVLQGKLAELSQRFQQLQLQQQ 1793
eRrqkLe<-*
e++ L+
mKIAA1251 1794 EKESNLK 1800
[output cut off at A = 10 top alignments]
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