hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/meh/meh00539/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1251  ( 1900 res)   meh00539

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
Spectrin Spectrin repeat                                 28.0    0.00023   6

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Spectrin   1/6     330   434 ..     1   108 []     6.0     0.21
Spectrin   2/6    1072  1184 ..     1   108 []    -4.1      1.2
Spectrin   3/6    1197  1309 ..     1   108 []    17.3     0.03
Spectrin   4/6    1465  1568 ..     1   108 []    20.3    0.017
Spectrin   5/6    1582  1692 ..     1   108 []    29.8  6.2e-05
Spectrin   6/6    1695  1801 ..     1   108 []    -4.2      1.3

Alignments of top-scoring domains:
Spectrin: domain 1 of 6, from 330 to 434: score 6.0, E = 0.21
                   *->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
                      + l++F   a  ++ W++ ke++    d  ++  ++ a+ + + ++ 
   mKIAA1251   330    QSLHKFVSRATAELIWLNGKEEEELACDWSDSNPNISAKKTYFSELT 376  

                   aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
                    el++ q d ++ l+++a+ L  e+  hp++  +++  +++ ++ +++++
   mKIAA1251   377 MELEGKQ-DVFRFLQDTAEVLSLEN--HPAKQTVEAYSAAVQSQLQWMKQ 423  

                   laaeRkqkLee<-*
                   l+   +q + e   
   mKIAA1251   424 LCLCVEQHVKE    434  

Spectrin: domain 2 of 6, from 1072 to 1184: score -4.1, E = 1.2
                   *->lllqqFqrdadelesW...isekeallssedygkDlesvqaLlkkHe
                      ++ q+   ++++l+ W +++    +  +  ++    +++++ +  ++
   mKIAA1251  1072    EEKQEHVEKVKDLLGWvstLARNTQGTTTSSHTSASADIEKAILEQQ 1118 

                   afeaelaahqqdrvdqlnelaqkLieeged...hpdseeikerleeLner
                    + +el + + ++v++  ++ q ++++++++ +  ++e+i e+l  Ln+ 
   mKIAA1251  1119 VLAEELTTKK-EQVSEAIKTSQIFLAKHGHklsEGEKEQISEQLRVLNKT 1167 

                   WeaLlelaaeRkqkLee<-*
                   + +L++  a + q+L+    
   mKIAA1251  1168 YHDLCDGSANQLQQLQS    1184 

Spectrin: domain 3 of 6, from 1197 to 1309: score 17.3, E = 0.03
                   *->lllqqFqrdadelesWisekeallssedygk...DlesvqaLlkkHe
                      +++   ++++++l +W +++e+ l++ + g ++++l ++q+ +  ++
   mKIAA1251  1197    KQQDTCHKKLEDLCNWVGQAERALERHQGGAsrqELPALQQNQSDLK 1243 

                   afeaelaahqqdrvdqlnelaqkLieeged...hpdseeikerleeLner
                   +++ +++ h  + + +  +  + ++ee++++ ++++  +++e+l +  e+
   mKIAA1251  1244 DLQGDIQSHS-TSFATAVKDIEGFLEENQTklsPQELTALREKLHQAKEQ 1292 

                   WeaLlelaaeRkqkLee<-*
                   +e L+e++   +++Lee   
   mKIAA1251  1293 YEVLQERTRVAQKELEE    1309 

Spectrin: domain 4 of 6, from 1465 to 1568: score 20.3, E = 0.017
                   *->lllqqFqrdadelesWisekeallssedygk.DlesvqaLlkkHeaf
                       +lq+F +d +e+e+W+++ e++l s+ +g++++e++ +Llk++  f
   mKIAA1251  1465    DELQKFLQDHKEFENWLQQSENELDSMHKGGsSPEALNSLLKRQGSF 1511 

                   eaelaahqqdrvdqlnelaqkLieeged...hpdseeikerleeLnerWe
                    +++  h+ + ++ ++  +qk++e     +++++  +++  ++e      
   mKIAA1251  1512 SEDVISHK-GDLRFVTISGQKVLETENNfeeGQEPSATRNLVNE------ 1554 

                   aLlelaaeRkqkLee<-*
                   +L++++ eR   L+    
   mKIAA1251  1555 KLKDAT-ERYTTLHS    1568 

Spectrin: domain 5 of 6, from 1582 to 1692: score 29.8, E = 6.2e-05
                   *->lllqqFqrdadelesWisekea...llssedygkDlesvqaLlkkHe
                       ++qqFq  ad l++W    ea+ + l s+  + D+  +q++l   +
   mKIAA1251  1582    GQYQQFQSSADSLQAWVLTCEAsvgKLLSDTVASDPGVLQQQLATTK 1628 

                   afeaelaahqqdrvdqlnelaqkLieeged.hpdseeikerleeLnerWe
                   ++++ela hq   v+ l++ a +L++  +++  d   i+e+ + + +r++
   mKIAA1251  1629 QLQEELAEHQ-VPVEKLQKAAHDLLDIEGEpALDCRPIQETTDSISSRFQ 1677 

                   aLlelaaeRkqkLee<-*
                   +L   ++eR ++L+    
   mKIAA1251  1678 NLSCSLDERSALLQK    1692 

Spectrin: domain 6 of 6, from 1695 to 1801: score -4.2, E = 1.3
                   *->lllqqFqrdadelesWisekeallssedygk.DlesvqaLlkkHeaf
                       + q  q  ++ l++ i+e e+ l++++ +  +   +q  l     +
   mKIAA1251  1695    AQSQSVQESMESLLQSIREVEQNLERDQVASlSSGVIQEALANNMKL 1741 

                   eaelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLl
                   ++++a ++   +++  ++  +++e   +  ++  ++ +l+eL +r+++L+
   mKIAA1251  1742 KQDIARQK-SSLEATHDMVTRFMETADS-NSASVLQGKLAELSQRFQQLQ 1789 

                   elaaeRkqkLee<-*
                    + +e++ +L     
   mKIAA1251  1790 LQQQEKESNLKK    1801 

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