hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg09359/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1249  ( 1079 res)   mbg09359

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
ArfGap   Putative GTP-ase activating proteins for the   128.9    5.5e-34   1
SH3      Src homology 3 domains                          72.4    5.6e-17   1
PH       Pleckstrin homology domain.                     65.9      5e-15   1
ANK      ankyrin repeats                                 49.8    3.7e-10   2

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PH         1/1     272   365 ..     1    82 []    65.9    5e-15
ArfGap     1/1     386   509 ..     1   139 []   128.9  5.5e-34
ANK        1/2     547   579 ..     1    30 []    20.7     0.21
ANK        2/2     583   612 ..     1    30 []    29.1   0.0006
SH3        1/1    1020  1078 ..     1    58 []    72.4  5.6e-17

Alignments of top-scoring domains:
PH: domain 1 of 1, from 272 to 365: score 65.9, E = 5e-15
                   *->vikeGwLlkks...k.swkkryfvLfngvLlyyksk..kpkgsipLs
                       +k+G+Llkks++ ++ w++r + ++ng L++ +  +++   +++L 
   mKIAA1249   272    SEKKGFLLKKSdgiRkVWQRRKCAVKNGILTISHATsnRQPAKLNLL 318  

                   gcsvre.p....cFeivt.drtlllqAeseeereeWvealqsaiaka<-*
                   +c+v+++++++++F +++++rt+++qAe+e++   W++ l +  ++a   
   mKIAA1249   319 TCQVKPnAedkkSFDLIShNRTYHFQAEDEQDYIAWISVLTNSKEEA    365  

ArfGap: domain 1 of 1, from 386 to 509: score 128.9, E = 5.5e-34
                   *->eealqlLRsikpgNkkCfDCGavpnPtWaSvnlGvflCieCSGiHRs
                      ++ ++ +++++ gN  C+DCG+  +PtW S nlG++ CieCSGiHR 
   mKIAA1249   386    KAIIEDVQRLP-GNDICCDCGS-SEPTWLSTNLGILTCIECSGIHRE 430  

                   LfGvHiSkVnvRSltLDtWteeeLrllesckgGNenansfwesnlddfsl
                   + GvHiS++   Sl LD+    eL l +  ++GN+ +n++ e+nl+ +s 
   mKIAA1249   431 M-GVHISRI--QSLELDKLGTSELLLAK--NVGNNSFNDIMEANLPSPSP 475  

                   kpkdsdaaasvKCeddrqkyesfiaaKYeeklf.rvdkesaee<-*
                   kp++s+         d  +++++i aKY++++f+r  + s+++   
   mKIAA1249   476 KPTPSS---------DMTVRKEYITAKYVDHRFsRKTCASSSA    509  

ANK: domain 1 of 2, from 547 to 579: score 20.7, E = 0.21
                   *->dGrTpLHlAaen...gnlevvklLldkgadina<-*
                       G T+LHlA+++ ++ +l++v +L+++ +++++   
   mKIAA1249   547    LGETALHLAVRTadqTSLHLVDFLVQNCGNLDK    579  

ANK: domain 2 of 2, from 583 to 612: score 29.1, E = 0.0006
                   *->dGrTpLHlAaengnlevvklLldkgadina<-*
                       G+T LH++ ++g +e++klLl++++++++   
   mKIAA1249   583    VGNTVLHYCSMYGKPECLKLLLRSKPTVDI    612  

SH3: domain 1 of 1, from 1020 to 1078: score 72.4, E = 5.6e-17
                   *->eyvvAlYDyeaqnedELsFkkGDiitvleksddgWweGelnr.tGke
                      ++v+ +YD++a+n+dEL+F +G++i+v+ ++d++Ww G + ++  ++
   mKIAA1249  1020    RRVKTIYDCQADNDDELTFIEGEVIIVTGEEDQEWWIGHIEGqPERK 1066 

                   GlfPsnYVeeie<-*
                   G fP ++V ++    
   mKIAA1249  1067 GVFPVSFVHILS    1078 

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