hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbj/mbj01002/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1246  ( 833 res)   mbj01002

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
LRR_TYP  Leucine-rich repeats, typical (most populate    87.9    1.2e-21   6
IGc2     Immunoglobulin C-2 Type                         54.1    1.8e-11   1
IG       Immunoglobulin                                  42.9    4.3e-08   1
LRRCT    Leucine rich repeat C-terminal domain           28.0     0.0013   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
LRR_TYP    1/6     120   143 ..     1    24 []    13.8      8.6
LRR_TYP    2/6     144   167 ..     1    24 []    24.7    0.013
LRR_TYP    3/6     168   191 ..     1    24 []    23.7    0.026
LRR_TYP    4/6     193   216 ..     1    24 []     7.4       52
LRR_TYP    5/6     217   240 ..     1    24 []    24.2    0.018
LRR_TYP    6/6     241   265 ..     1    24 []    12.5       12
LRRCT      1/1     287   332 ..     1    55 []    28.0   0.0013
IGc2       1/1     346   411 ..     1    56 []    54.1  1.8e-11
IG         1/1     340   422 ..     1    58 []    42.9  4.3e-08

Alignments of top-scoring domains:
LRR_TYP: domain 1 of 6, from 120 to 143: score 13.8, E = 8.6
                   *->LpnLreLdLsnNqLtsLPpgaFqg<-*
                      ++ L  L Ls+N ++++ p  F +   
   mKIAA1246   120    MTGLVDLTLSRNTISHIQPFSFLD    143  

LRR_TYP: domain 2 of 6, from 144 to 167: score 24.7, E = 0.013
                   *->LpnLreLdLsnNqLtsLPpgaFqg<-*
                      L +Lr+L+L++N+L sL +++++g   
   mKIAA1246   144    LESLRSLHLDSNRLPSLGEDTLRG    167  

LRR_TYP: domain 3 of 6, from 168 to 191: score 23.7, E = 0.026
                   *->LpnLreLdLsnNqLtsLPpgaFqg<-*
                      L+nL++L  +nNqL  + ++aF++   
   mKIAA1246   168    LVNLQHLIVNNNQLGGIADDAFED    191  

LRR_TYP: domain 4 of 6, from 193 to 216: score 7.4, E = 52
                   *->LpnLreLdLsnNqLtsLPpgaFqg<-*
                      L  L+ LdLs+N+L  LP +  +    
   mKIAA1246   193    LLTLEDLDLSYNNLHGLPWDSVRR    216  

LRR_TYP: domain 5 of 6, from 217 to 240: score 24.2, E = 0.018
                   *->LpnLreLdLsnNqLtsLPpgaFqg<-*
                      ++nL  L+L++N L ++ +g+F++   
   mKIAA1246   217    MVNLHQLSLDHNLLDHIAEGTFAD    240  

LRR_TYP: domain 6 of 6, from 241 to 265: score 12.5, E = 12
                   *->LpnLreLdLsnNqLtsLPpg.aFqg<-*
                      L +L +LdL +N+L+ LPp+++F+    
   mKIAA1246   241    LQKLARLDLTSNRLQKLPPDpIFAR    265  

LRRCT: domain 1 of 1, from 287 to 332: score 28.0, E = 0.0013
                   *->NPfnCDCeLrwLlrwleaqnnealqdpvsslrCasPeslrGqpllll
                      NP++C+CeL+wL+r+ ++       d     +C sP+sl+G   ++ 
   mKIAA1246   287    NPLHCNCELLWLRRLERD-------DD--LETCGSPGSLKGRYFWHI 324  

                   lpsefsCp<-*
                      ef+C+   
   mKIAA1246   325 REEEFVCE    332  

IGc2: domain 1 of 1, from 346 to 411: score 54.1, E = 1.8e-11
                   *->leGqsVtLtCpasgdpvpnItWlk.gkplp.........sgstLtik
                      leGq++tL+C+a gdp p I+W+ ++ +l ++++++   +++tL i 
   mKIAA1246   346    LEGQAATLKCKAIGDPSPLIHWVApDDRLVgnssrtavyDNGTLDIL 392  

                   nvsleDsGlYtCvArNsvg<-*
                     +  DsG  tC+A N++g   
   mKIAA1246   393 ITTSQDSGPFTCIAANAAG    411  

IG: domain 1 of 1, from 340 to 422: score 42.9, E = 4.3e-08
                   *->pp.vtvkeGesvtLtC.as.....titWy..................
                        +++v eG+ +tL+C+a +++++ i+W  ++++  ++++++   ++
   mKIAA1246   340    THkLLVLEGQAATLKCkAIgdpspLIHWVapddrlvgnssrtavydn 386  

                   ..LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-*
                   ++L I   t +Ds   G +tC a + +g+a++  ++++++    
   mKIAA1246   387 gtLDIlITTSQDS---GPFTCIAAnaAGEATA--TVEVSIV    422  

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