hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbp/mbp00320/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1243  ( 1080 res)   mbp00320

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
SAP      SAP domain                                      55.4    1.3e-12   1
RPEL     RPEL repeat                                     41.0    2.7e-08   3
SSDP     Single-stranded DNA binding protein, SSDP     -107.2       0.86   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
RPEL       1/3      40    65 ..     1    26 []     8.9      2.5
RPEL       2/3      84   109 ..     1    26 []    11.5      1.1
RPEL       3/3     128   153 ..     1    26 []    23.2   0.0059
SAP        1/1     383   417 ..     1    35 []    55.4  1.3e-12
SSDP       1/1     261   537 ..     1   487 []  -107.2     0.86

Alignments of top-scoring domains:
RPEL: domain 1 of 3, from 40 to 65: score 8.9, E = 2.5
                   *->dlLarKLSqRPtreELerrnILkeee<-*
                       +L  +L+qR tre L +++I   ++   
   mKIAA1243    40    EVLQLRLQQRRTREQLVDQGIMPPLK    65   

RPEL: domain 2 of 3, from 84 to 109: score 11.5, E = 1.1
                   *->dlLarKLSqRPtreELerrnILkeee<-*
                        L+ K+  RP r EL r +IL+e+    
   mKIAA1243    84    NFLKHKIRSRPDRSELVRMHILEETF    109  

RPEL: domain 3 of 3, from 128 to 153: score 23.2, E = 0.0059
                   *->dlLarKLSqRPtreELerrnILkeee<-*
                      d L+ K+ qRP++ EL ++nIL  ++   
   mKIAA1243   128    DDLNEKIAQRPGPMELVEKNILPVDS    153  

SAP: domain 1 of 1, from 383 to 417: score 55.4, E = 1.3e-12
                   *->lskLkVseLKeeLkkrGLstsGkKaeLveRLleal<-*
                      l+ LkVseLK eLk rGL++sG+K++L+eRL+ +    
   mKIAA1243   383    LDDLKVSELKTELKLRGLPVSGTKPDLIERLKPYQ    417  

SSDP: domain 1 of 1, from 261 to 537: score -107.2, E = 0.86
                   *->gseevsAYmSyIetlrkKaRlnLQeiQknslseakafhdYsaAaaPs
                      g  ++    S+  +   K R +  +  k+ +   k+ +         
   mKIAA1243   261    G--PMLVKQSHPKNPNDKHRSKKCKDPKPRVKKLKYHQY-------- 297  

                   pvlgamqqqidmsqlhigaGfFQPflsqRaqhlqrqPhnPnamlnpqsRe
                        ++++                         +q      m  +    
   mKIAA1243   298 -----IPPNQKGEKS------------------EPQ------MDSN---- 314  

                   tFPPtAAqLQQlkqlHyrQlQsvQQQQkQqQQkktqQsqsqPpsqlpgsQ
                         A+L Q++ql + QlQ   QQQ+QqQQ            q    Q
   mKIAA1243   315 -----YARLLQQQQL-FLQLQILSQQQQQQQQ------------QHYNYQ 346  

                   PltPdtHqqqPtkQQqPirddrSilaspraqGhPgmngFrPmlRatPprG
                     +P            Pi+ d+ + +        ++ g   +++a  p+ 
   mKIAA1243   347 TILPA-----------PIKTDKNSSS-------GSNSGSSSSMPARRPGP 378  

                   meqsnPLYDttGLnGGqYPvvqnsAqPLLHeinFAsnRnPHLkskaaver
                    +                                                
   mKIAA1243   379 LP------------------------------------------------ 380  

                   vklPtQrkSLDkPkPAqqPaagk.....rmGpqpqnyGgglrPppnslLY
                           SLD+ k        k ++ + +G +p     +l+P++     
   mKIAA1243   381 -------SSLDDLKVSELKTELKlrglpVSGTKPDLI-ERLKPYQEVT-- 420  

                   nFlksAAgpGlPAmnmLHstsGGMgPgRLnPALknYmeeLkLLeqqnkkR
                       + A     A+    +t    +P                        
   mKIAA1243   421 --SSNLATGSIVAVSS--ATIVTSNPE----------------------- 443  

                   LLLvsqekeRkGYtsAsPDRPLsqtitessvAktksttPkstDtPteAtt
                                t A P   L  ++t ssv   k               
   mKIAA1243   444 ------------VTVALPVTTLHNAVT-SSVSTFK--------------- 465  

                   sPvkvptpnpsttnsLpgsassnipGsyigPmLqnGLPllTPggggPfpG
                     +    p  s   s p +           P     LP+  ++  ++   
   mKIAA1243   466 --ADLALPATS---SVPHVENA--H----SP-----LPISPSPSEQS--- 496  

                   tlImpsPgsstnssdntlkvmnltgfsqtrSnfplgpnpkgpsqv<-*
                         ++++tn  d+   +m  + +sq+  + pl+  +   s +   
   mKIAA1243   497 ----SLSTDDTNMTDTFTEIMTMMSPSQLLCSSPLRVVSHDDSLS    537  

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