hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/smart.HMMs Sequence file: /cdna4/rodent/full/goal/mbp/mbp17192/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA1233 ( 747 res) mbp17192 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- IGc2 Immunoglobulin C-2 Type 75.0 9e-18 2 IG Immunoglobulin 53.0 4e-11 2 TSP1 Thrombospondin type 1 repeats 35.2 8.9e-06 3 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- IGc2 1/2 260 325 .. 1 56 [] 14.7 0.16 IG 1/2 254 337 .. 1 58 [] 13.7 5.5 IGc2 2/2 367 429 .. 1 56 [] 60.4 2.3e-13 IG 2/2 361 442 .. 1 58 [] 39.4 4.8e-07 TSP1 1/3 482 539 .. 1 66 [] 22.8 0.031 TSP1 2/3 541 600 .. 1 66 [] 20.5 0.054 TSP1 3/3 657 712 .. 1 66 [] 7.6 1.5 Alignments of top-scoring domains: IGc2: domain 1 of 2, from 260 to 325: score 14.7, E = 0.16 *->leGqsVtLtCp.asgdpvpnItWlk.gkplp........sgstLtik ++ + + + C + + +++ tW+k+g l+++ + + + +i+ mKIAA1233 260 KSTEIINILCSlITPSKEATYTWTKdGALLQpsvkiildETGKMQIR 306 nvsleDsGlYtCvArNsvg<-* n ++ G+Y+C++ ++ g mKIAA1233 307 NPTRKEQGIYECSVASHLG 325 IG: domain 1 of 2, from 254 to 337: score 13.7, E = 5.5 *->pp.vtvkeGesvtLtC.as......titWy................. + k e +++ C+ ++++ t+tW++++ +++ + + + mKIAA1233 254 NTvYITKSTEIINILCsLItpskeaTYTWTkdgallqpsvkiildet 300 ..LtI.nvtpeDsesgGtYtCaat...sgsasseqgttLtVl<-* ++++I+n t+ + G+Y C + ++ + +++s + L+ + mKIAA1233 301 gkMQIrNPTRKEQ---GIYECSVAshlGSDVES--SLVLYAE 337 IGc2: domain 2 of 2, from 367 to 429: score 60.4, E = 2.3e-13 *->leGqsVtLtCpasgdpvpnItWlk.gkplp......sgstLtiknvs +Vt+ Cp+ g p pn+tWlk+g +l+++ + +++L ++++s mKIAA1233 367 ALQANVTIHCPVKGVPQPNVTWLKrGGSLSdnvsllFNGSLLLQSAS 413 leDsGlYtCvArNsvg<-* le +G+Y C+A+N+ g mKIAA1233 414 LENEGTYICTATNALG 429 IG: domain 2 of 2, from 361 to 442: score 39.4, E = 4.8e-07 *->pp.vtvkeGesvtLtC.as.....titWy.................L ++v++ + +vt++C++++ + +++tW++++++ +++ + +++L mKIAA1233 361 GGtVEAALQANVTIHCpVKgvpqpNVTWLkrggslsdnvsllfngsL 407 tI.nvtpeDsesgGtYtCaat....sgsasseqgttLtVl<-* ++++++e++ GtY C+at+ ++ +a+s g +L + mKIAA1233 408 LLqSASLENE---GTYICTATnalgKAVATS--GLRLLER 442 TSP1: domain 1 of 3, from 482 to 539: score 22.8, E = 0.031 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg +e + W+ CS +tCG g + +R R c+++ ++ ++ + mKIAA1233 482 FWEPGNWTHCS-ATCGPLGV---RLQRPR-----CVMASGQ--EVSE 517 epCs.......EtrpCntqpnLqpCp<-* + C +++++ ++ Cn + +Cp mKIAA1233 518 ALCGphrkplaGFQSCNIR----DCP 539 TSP1: domain 2 of 3, from 541 to 600: score 20.5, E = 0.054 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg + +s WS+CS v+CG+G + +R+ + c+ + ng mKIAA1233 541 RWFTSVWSECS-VSCGEG-----FHSRQVT----CKQTKA----NGT 573 epCs............EtrpCntqpnLqpCp<-* + +++ +++++ +pC+ + pC mKIAA1233 574 VQVVspracapkdrplGRKPCSIR----PCV 600 TSP1: domain 3 of 3, from 657 to 712: score 7.6, E = 1.5 *->wseWseWSpCSgvtCGgGgrtegvrtRtRsslrvccspppprnqngg ++ ++W pC+ + CG+G +++R+ c + mKIAA1233 657 CWRVGPWKPCT-AVCGRG-----FQSRKV-----DCIH--------T 684 epCs.............EtrpCntqpnLqpCp<-* ++C ++ + ++ r C+++ C+ mKIAA1233 685 GSCKivadrycvqvkpaAWRHCFGP----SCD 712 //