hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg08960/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1209  ( 1220 res)   mbg08960

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PH       Pleckstrin homology domain.                     36.7    3.2e-06   1
RhoGEF   Guanine nucleotide exchange factor for Rho/R    29.5    0.00033   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
RhoGEF     1/1       1   121 [.     1   211 []    29.5  0.00033
PH         1/1     153   247 ..     1    82 []    36.7  3.2e-06

Alignments of top-scoring domains:
RhoGEF: domain 1 of 1, from 1 to 121: score 29.5, E = 0.00033
                   *->vlkELlqTErnYVrdLkilvevflkpLkkeakssllpllspdevktl
                                                                     
   mKIAA1209     -    ----------------------------------------------- -    

                   FgpNieeiyefHrrFLdeLeerveewllskdlKsernsviedsgerigdv
                                ++L++Le + ++                  +  i+ +
   mKIAA1209     1 -------------ELLQDLENCEND------------------PVAIAEC 19   

                   FlklfsaeeffkiYseYcsnhpdalellkkLmkkkknpaFqkflkeiesk
                   F+     +e f+iY++Yc n+p+++++l++ m    n+ + kf++e+++ 
   mKIAA1209    20 FVSK---SEEFHIYTQYCTNYPRSVAVLTECM---RNKILTKFFRERQET 63   

                   pncrsksearltLeslLikPvQRltkYpLLLkellkhtppdhedredLkk
                    +++      l+L s+L+kPvQR++kY+LLL+e++ h +++ e ++ + +
   mKIAA1209    64 LRHS------LPLGSYLLKPVQRILKYHLLLHEIENHLDKATEGYDVVLD 107  

                   AleaikelasqvNe<-*
                   A++ ++++a ++N+   
   mKIAA1209   108 AIDTMQRVAWHIND    121  

PH: domain 1 of 1, from 153 to 247: score 36.7, E = 3.2e-06
                   *->vikeGwLlkkskswkkryfvLfngvLlyyksk....kpkgsipLsgc
                      +++eG+ ++++   k+r ++L ++ Ll++k+++++ ++k  i   ++
   mKIAA1209   153    LVLEGTFRIQK-AKKERTLFLLDQLLLITKKRddtfTYKAHILCGNL 198  

                   .svre.p....cFeivt.dr...tlllqAeseeereeWvealqsaiaka<
                     v++ p+++ +F +++ ++++  +++qA+s+++++ Wv +l+++i ++ 
   mKIAA1209   199 mLVEViPkeplSFSVFHyKNpklQHTVQAKSQQDKRLWVLHLKRLILEN  247  

                   -*
                     
   mKIAA1209     -    -    

//