hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg09531/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1200  ( 1447 res)   mbg09531

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PH       PH domain                                      123.9      3e-33   2
MyTH4    MyTH4 domain                                    79.3      8e-20   1
ERM      Ezrin/radixin/moesin family                   -211.6       0.87   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
ERM        1/1     113   375 ..     1   390 []  -211.6     0.87
PH         1/2     664   757 ..     1    92 []    92.4  8.8e-24
PH         2/2     773   881 ..     1    92 []    31.7  1.7e-05
MyTH4      1/1     959  1071 ..     1   118 []    79.3    8e-20

Alignments of top-scoring domains:
ERM: domain 1 of 1, from 113 to 375: score -211.6, E = 0.87
                   *->NKKGTdLWLGVDALGLNIYekdDrLTPKIGFPWSEIRNISFnDKKFv
                          T L                                        
   mKIAA1200   113    ----TQL---------------------------------------- 115  

                   IKPiDKKApdFvFYaprlRINKRILaLCmGNHELYMRRRKPDTIEVQQMK
                             F F  + ++I                              
   mKIAA1200   116 ----------FRFRLQASKI------------------------------ 125  

                   aQArEEKalKqaERekLerEkkaREiaekekEeaEreqqEleerlkqmeE
                      rE  a K +E      E+           eaE++ + +e +   meE
   mKIAA1200   126 ---RELLADKMQE-----LEQRLL--------EAEQRAENAETQVGVMEE 159  

                   dmrraqkeLeeseekale.LeeklkqeqeaaqkLekkqkeleeenr.rLe
                   + + ++++  +s+ + ++++ e+lk  q   ++  + q+ le  +++r e
   mKIAA1200   160 KIKLSNLKSVDSTGTLHQkYQELLKAVQGKDELISQLQAQLEKQKQtRAE 209  

                   eeaaaseeErerLeaevde.ataevakleeerekkeeEteqlqaelreaq
                   e+++ +e+     +a++ e +t++ a le+e++   +   ql ++++  q
   mKIAA1200   210 EAKIVQEK-----AAKIKEwVTVKLAELEMENQQLKTCNQQLVEQVAALQ 254  

                   ekeee.akeellevlaap.......................tappmhhvs
                   +++e   + +  e+l  p++++++++ ++++++++ ++++++  +   v+
   mKIAA1200   255 DALEDlRMTPSEELLVVPegtperdpvpsgpsdqpveqdsnPHTQILKVA 304  

                   apeaELttdngeqleqddngeeasadlePkEFiLtdedmkdrsnEiEeeR
                    p      + + + +q+ +++++++ le            d        R
   mKIAA1200   305 VP------TPSLGTLQSRDSLSEARSLE------------DL-------R 329  

                   vteaeknerlqtqLkaLksELaavrdesKetanDilHeENsvRaGrDKYk
                    +++ + e+   +  +L+s L+    +s         +   ++ G+ K+ 
   mKIAA1200   330 FSMVHPGETAEAK--TLQSHLQKEGSPS---------QLC-MKPGNPKH- 366  

                   TLRqIRkGNTKqRVDqFEsM<-*
                          G++  R    Es+   
   mKIAA1200   367 -------GSASYR----ESL    375  

PH: domain 1 of 2, from 664 to 757: score 92.4, E = 8.8e-24
                   *->vikeGwLlkkg.gkkswkkRyfvLfndvLlyykdkk...kkpkgsip
                      ++k+G+Llk+g++ k+wk+R+fvL+++++lyyk++++   kp+g ++
   mKIAA1200   664    LEKSGYLLKMGsRVKTWKRRWFVLRQGQILYYKSPSdviRKPQGQVD 710  

                   Lsgi.qvekvpdnkrkncFeirt.dretlllqaeseeerkeWvkaiqsai
                   L++  q+++ ++     +F+++++++ t++l aes+  ++eW++ +qs++
   mKIAA1200   711 LNSHcQIVREEE---AQTFQLISgNK-TYYLTAESPSLLEEWIRVLQSLL 756  

                   r<-*
                   +   
   mKIAA1200   757 K    757  

PH: domain 2 of 2, from 773 to 881: score 31.7, E = 1.7e-05
                   *->vikeGwLlkkggkkswkkRyfvLfndvLlyykdkk.kkpkgsipLsg
                      ++ +GwL+k    +  k +++ L +++++yy++  +k+p g++p+++
   mKIAA1200   773    PTVKGWLTKVK-HGHSKLVWCALVGKTFYYYRSHEdKRPLGCLPVQD 818  

                   iqvekvpdn................krkncFeirt.dretlllqaeseee
                   + +e+v+++ +++++ + +++++    +++++i+ +++   +l   +  e
   mKIAA1200   819 AHIEEVDRScdsdedyeaggtgrllSSHCTLVIHPpEHSPTYLLIGTKHE 868  

                   rkeWvkaiqsair<-*
                   +++W+ ++  a+    
   mKIAA1200   869 KDTWLYHLTVAAG    881  

MyTH4: domain 1 of 1, from 959 to 1071: score 79.3, E = 8e-20
                   *->rsridlvqkIlkqgikrpeLRDEiYCQiiKQltkNPsqkkqSalrGW
                      ++   l+q  l+ ++  peL  EiYCQ+ KQ++  P   k+S+   W
   mKIAA1200   959    DYHVSLAQTALQVCLVHPELQSEIYCQLMKQISCRPP-QKYSLMQCW 1004 

                   eLlylctgtFpPSeellkyLsEqFlhrraheqlsgpelegyaadcqerLk
                   +Ll lc+ +F+P   +l y++ q l+r a+   + +e  +ya++cq++ +
   mKIAA1200  1005 QLLALCAPLFLPQHHFLWYVK-QQLQRHAD---PRSETGQYAIYCQRAVE 1050 

                   ktqknGsRkypPsrlEieAik<-*
                   +t   G R+  Psr E+ +i+   
   mKIAA1200  1051 RTLQTGEREARPSRMEVVSIL    1071 

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