hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbp/mbp00156/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1186  ( 404 res)   mbp00156

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
CRAL_TRIO   CRAL/TRIO domain                            153.2    4.4e-42   1
EMP24_GP25L emp24/gp25L/p24 family                       97.8    2.1e-25   1
CRAL_TRIO_N CRAL/TRIO, N-terminus                        50.9    2.9e-11   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
CRAL_TRIO_N   1/1       4    72 ..     1    89 []    50.9  2.9e-11
CRAL_TRIO     1/1      86   281 ..     1   188 []   153.2  4.4e-42
EMP24_GP25L   1/1     298   384 ..     1    92 []    97.8  2.1e-25

Alignments of top-scoring domains:
CRAL_TRIO_N: domain 1 of 1, from 4 to 72: score 50.9, E = 2.9e-11
                   *->gtpgnltpeqeraykskLkeetLkelryelseknkteeldkgykerl
                      g+ g l+p q         ee+L+++r++++        d+  + + 
   mKIAA1186     4    GRVGDLSPKQ---------EEALAKFRENVQ--------DVLPTLPN 33   

                   kawldDatlLRFLRARKFdvaaAiemltktlkWRrEfGvnei<-*
                      +dD +lLR LRAR Fd++++  ml+k +++R++  +++i   
   mKIAA1186    34 ---PDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDKI    72   

CRAL_TRIO: domain 1 of 1, from 86 to 281: score 153.2, E = 4.4e-42
                   *->pqfihgtdkdGrpvylekrGklntkvmlkittlhrmlkklvyeverl
                       +   g+d dG pv +   G+l++k++l+ ++++++l  ++   ++l
   mKIAA1186    86    SGGRCGYDLDGCPVWYDIIGPLDAKGLLF-SASKQDLLRTKMRDCEL 131  

                   tlyrlpaasrklgtlingsctvfDlkGvsmssmaspvlsvlkkvinilqd
                   +l+   +++ klg+ i++++ ++D +G++++++++p +  + + + +++ 
   mKIAA1186   132 LLQECIQQTTKLGKKIETITMIYDCEGLGLKHLWKPAVEAYGEFLTMFEE 181  

                   yYPErlgkfylinaPwlFstvyklIKpFLDektrsKifvlGssYkeeLlk
                   +YPE+l+++++++aP lF+++y+lIKpFL+e+tr Ki+vlG + ke Llk
   mKIAA1186   182 NYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRRKIMVLGANWKEVLLK 231  

                   hipaenLPakfGGt.........lktkydkcgvwlsdvgpwrdeeqigfe
                   hi +++LP ++GGt +++++++++k+k +++g  ++++  +++++q ++ 
   mKIAA1186   232 HISPDQLPVEYGGTmtdpdgnpkCKSKINYGGDIPKQYYVRDQVKQQYEH 281  

                   <-*
                      
   mKIAA1186     -     -    

EMP24_GP25L: domain 1 of 1, from 298 to 384: score 97.8, E = 2.1e-25
                   *->eeggstlsWefrtgdldidfgiyfsktecvsedeevhtspdgpvihs
                       ++g++l+W+f++ + d++fgi+ ++ + +++ +++ + ++ p  ++
   mKIAA1186   298    LFPGCVLRWQFMSEGSDVGFGIFLKTKMGERQRAGE-MTEVLPNQRY 343  

                   eskkssgevidfsFtapepGeYklCFdNsyStftsKtvrfielev<-*
                   +s+ +++   d+++t++epG+Y+l FdN+yS ++ K+v+f ++ev   
   mKIAA1186   344 NSHMVPE---DGTLTCSEPGIYVLRFDNTYSFIHAKKVSF-TVEV    384  

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