hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mph/mph01717/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1185  ( 521 res)   mph01717

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
LRR_1    Leucine Rich Repeat                             74.6      2e-18   7
B3_4     B3/4 domain                                    -21.0     0.0044   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
LRR_1      1/7      18    41 ..     1    25 []     9.5       54
LRR_1      2/7      42    63 ..     1    25 []    14.3      2.9
LRR_1      3/7      72    94 ..     1    25 []    17.2      0.4
LRR_1      4/7      96   118 ..     1    25 []    10.6       35
LRR_1      5/7     122   144 ..     1    25 []     2.4    8e+02
LRR_1      6/7     145   167 ..     1    25 []    22.0    0.015
LRR_1      7/7     168   192 ..     1    25 []     6.6  1.6e+02
B3_4       1/1     271   444 ..     1   189 []   -21.0   0.0044

Alignments of top-scoring domains:
LRR_1: domain 1 of 7, from 18 to 41: score 9.5, E = 54
                   *->nLeeLdLsgCNpslsgs.lppsl.glp<-*
                      +L +L L++ N  l g++l+p+l+ lp   
   mKIAA1185    18    QLHSLVLRR-N-AL-GPgLSPELgPLP    41   

LRR_1: domain 2 of 7, from 42 to 63: score 14.3, E = 2.9
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                       L++LdLsg N  l+ +lpp  +gl    
   mKIAA1185    42    ALRVLDLSG-N-ALE-TLPP-GeGLG    63   

LRR_1: domain 3 of 7, from 72 to 94: score 17.2, E = 0.4
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      +L++L+Lsg N +l ++lp++l  +    
   mKIAA1185    72    QLQSLNLSG-N-RL-RELPADLaRCA    94   

LRR_1: domain 4 of 7, from 96 to 118: score 10.6, E = 35
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      +L++L+L g N +l + +pp+l       
   mKIAA1185    96    RLQSLNLTG-N-RL-DAFPPELfRPG    118  

LRR_1: domain 5 of 7, from 122 to 144: score 2.4, E = 8e+02
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                       L eL   + N  l ++l+p++ +l    
   mKIAA1185   122    LLSELAAAD-N-CL-RELSPDIaHLA    144  

LRR_1: domain 6 of 7, from 145 to 167: score 22.0, E = 0.015
                   *->nLeeLdLsgCNpslsgslppsl.glp<-*
                      +L++LdLs+ N +l+ ++p++l ++p   
   mKIAA1185   145    SLKTLDLSN-N-QLT-EIPAELaDCP    167  

LRR_1: domain 7 of 7, from 168 to 192: score 6.6, E = 1.6e+02
                   *->nLeeLdLsgCNpslsgs..lppsl.glp<-*
                      +L+e++++g N +l +++ l++  +g++   
   mKIAA1185   168    KLKEINFRG-N-RL-RDkrLEKMVgGCQ    192  

B3_4: domain 1 of 1, from 271 to 444: score -21.0, E = 0.0044
                   *->acprYagrviknvkikapSsiFILQKHPlWlqrrLraaGirpINnvV
                       +p+ +g ++++ +  +p         +++  rr  ++  +  + ++
   mKIAA1185   271    VRPYIVGAIVRGMDL-QPG--------NAL--RRFLNSQTKLHDDLC 306  

                   DiTNYvmLelGQPlHAFDldkiqfyngsggivV.................
                        +++ +      +Dl  +      g++    +++++ +  + ++++
   mKIAA1185   307 EKRTAATIAT------HDLQAV-----RGPLLYaarppedlkivplgrke 345  

                   ..............................RfAkegEklvtLDgkeereL
                    + ++  ++ + + +++++++++++ ++ +R      +l++LDgk     
   mKIAA1185   346 akakelvrqlqleaeeqrkqkkrqsvsglhR------YLHLLDGK----- 384  

                   degdLVIaDdekpVlalAGvmGGeesevtenTknifLEaAyFdPeaIrkt
                    e++++ +D+e+ V++ +++ ++e +++  +T n fLE++          
   mKIAA1185   385 -ENYPCLVDAEGDVISFPPITNSEKTKIKKTTCNLFLEVTS--------- 424  

                   srrlgLrteaSyRFERGvDpalvekAldrAteLllelag<-*
                                       ++++++ d+  +L+l+ a    
   mKIAA1185   425 -------------------ATNLQLCKDIMDSLILRMAE    444  

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