hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj27154/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1163  ( 638 res)   mfj27154

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
LRR_1    Leucine Rich Repeat                             48.4    1.6e-10   6
ig       Immunoglobulin domain                           28.8    0.00013   1
LRRNT    Leucine rich repeat N-terminal domain           15.9       0.34   1
V-set    Immunoglobulin V-set domain                      5.8       0.16   1
I-set    Immunoglobulin I-set domain                     -1.2      0.015   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
LRRNT      1/1     179   206 ..     1    34 []    15.9     0.34
LRR_1      1/6     208   232 ..     1    25 []     5.4  2.6e+02
LRR_1      2/6     233   256 ..     1    25 []    12.4       11
LRR_1      3/6     257   280 ..     1    25 []    15.1      1.7
LRR_1      4/6     281   304 ..     1    25 []     8.1       92
LRR_1      5/6     305   328 ..     1    25 []     9.8       47
LRR_1      6/6     332   355 ..     1    25 []    13.4      5.5
ig         1/1     429   488 ..     1    65 []    28.8  0.00013
I-set      1/1     420   504 ..     1    97 []    -1.2    0.015
V-set      1/1     416   504 ..     1   130 []     5.8     0.16

Alignments of top-scoring domains:
LRRNT: domain 1 of 1, from 179 to 206: score 15.9, E = 0.34
                   *->aCpapCtCserytdglvVdCsgrgLtvavPrdlP<-*
                       Cpa+C C           Cs+++L   vP  lP   
   mKIAA1163   179    SCPANCLCA-----SNILSCSKQQLP-NVPQSLP    206  

LRR_1: domain 1 of 6, from 208 to 232: score 5.4, E = 2.6e+02
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                          LdLs+ N +ls+  ++++   l+   
   mKIAA1163   208    YTALLDLSH-N-NLSRLRAEWtPtRLT    232  

LRR_1: domain 2 of 6, from 233 to 256: score 12.4, E = 11
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                      nL +L Ls+ N +l+  ++++++   p   
   mKIAA1163   233    NLHSLLLSH-N-HLN-FISSEaFvPVP    256  

LRR_1: domain 3 of 6, from 257 to 280: score 15.1, E = 1.7
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                      nL++LdLs+ N +l  +l +  +++l+   
   mKIAA1163   257    NLRYLDLSS-N-HLH-TLDEFlFsDLQ    280  

LRR_1: domain 4 of 6, from 281 to 304: score 8.1, E = 92
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                       Le+L L + N ++   +  ++++++    
   mKIAA1163   281    ALEVLLLYN-N-HIV-VVDRNaFeDMA    304  

LRR_1: domain 5 of 6, from 305 to 328: score 9.8, E = 47
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                      +L++L+Ls  N ++s  +p + +++     
   mKIAA1163   305    QLQKLYLSQ-N-QIS-RFPVElIkDGN    328  

LRR_1: domain 6 of 6, from 332 to 355: score 13.4, E = 5.5
                   *->nLeeLdLsgCNpslsgslpps.l.glp<-*
                      +L  LdLs+ N +l + lp  +l++lp   
   mKIAA1163   332    KLMLLDLSS-N-KL-KKLPLTdLqKLP    355  

ig: domain 1 of 1, from 429 to 488: score 28.8, E = 0.00013
                   *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyq
                      G+++t++C +      + t  W + + ++  ++ +  s++  +++  
   mKIAA1163   429    GDTLTIRCDT---KQQGMTKVWVSPSNeQVlSQGSNGSVSVRNGD-- 470  

                   tsLtitnvtpeDggtYtCvv<-*
                     L +++v+ eDgg+YtC++   
   mKIAA1163   471 --LFFKKVQVEDGGVYTCYA    488  

I-set: domain 1 of 1, from 420 to 504: score -1.2, E = 0.015
                   *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVsWfKd..Gqplssvl
                           k +  e+  G++++  C+ +     t  W   ++ q ls+  
   mKIAA1163   420    -----KESAWEAHLGDTLTIRCDTKQQ-GMTKVWVSPsnEQVLSQ-- 458  

                   lpsdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeaeasaeLt
                     ++  +v++++      L++++vq +D G+YtC+A  +    + s+eL+
   mKIAA1163   459 --GSNGSVSVRN----GDLFFKKVQVEDGGVYTCYAMGETFNETLSVELK 502  

                   Vq<-*
                   V+   
   mKIAA1163   503 VY    504  

V-set: domain 1 of 1, from 416 to 504: score 5.8, E = 0.16
                   *->qstvtqepprLLLASLfWptsvtvaeGgsvtLpCtysGtfddsssss
                      +s+  +  ++          +  + +G+++t++C  +         +
   mKIAA1163   416    CSEYKE--SA----------W-EAHLGDTLTIRCDTK--------QQ 441  

                   gtgsvyWyrqqppGekpeliii.syytyysysegngtvserfkgrvrfsg
                   g+ +  W+   p+        ++ +++++s++          + +vr   
   mKIAA1163   442 GM-TKVWVS--PS--------NeQVLSQGSNG----------SVSVR--- 467  

                   npskgdfsLtIsnlqlsDsGtYyCa........gggtrLtVl<-*
                        +  L  +++q++D G+Y+C   +++ ++  +++L V    
   mKIAA1163   468 -----NGDLFFKKVQVEDGGVYTCYamgetfneTLSVELKVY    504  

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