hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mph/mph00410/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA1142  ( 597 res)   mph00410

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    315.8    3.1e-90   1
PBD      P21-Rho-binding domain                          62.1    7.3e-14   1
TyrKc    Tyrosine kinase, catalytic domain               61.5    6.1e-15   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PBD        1/1      15    50 ..     1    38 []    62.1  7.3e-14
S_TKc      1/1     327   578 ..     1   231 []   315.8  3.1e-90
TyrKc      1/1     327   578 ..     1   280 []    61.5  6.1e-15

Alignments of top-scoring domains:
PBD: domain 1 of 1, from 15 to 50: score 62.1, E = 7.3e-14
                   *->IStPtGnFkHiaHVGPfDgatgeFtglptewesllkts<-*
                      IS+P+ nF+H++H G fD+++++Ftglp +w+sl+  s   
   mKIAA1142    15    ISAPS-NFEHRVHTG-FDQHEQKFTGLPRQWQSLIEES    50   

S_TKc: domain 1 of 1, from 327 to 578: score 315.8, E = 3.1e-90
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik.......erilrEi
                       +   k+G+G+ G V+ a+ +++g+lvA+K+++ ++++++e + +E+
   mKIAA1142   327    LDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDlrkqqrrELLFNEV 373  

                   kiLkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgrrgl
                    i++  +H+N+V +y ++  +d+l++VmE++eG  G L d+  + +    
   mKIAA1142   374 VIMRDyRHENVVEMYNSYLVgDELWVVMEFLEG--GALTDIVTHTR---- 417  

                   rkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds..hvKlaD
                      ++E++++ ++  +l+aL+ LH qg+iHRD+K + iLL+++++vKl+D
   mKIAA1142   418 ---MNEeQIAAVCLAVLQALAVLHAQGVIHRDIKSDSILLTHdgRVKLSD 464  

                   FGlArql.......ttfvGTpeYmAPEvl...gYgkpavDiWSlGcilyE
                   FG+++q++++ ++++++vGTp++mAPE++++ +Yg+ +vDiWSlG++++E
   mKIAA1142   465 FGFCAQVskevprrKSLVGTPYWMAPELIsrlPYGP-EVDIWSLGVMVIE 513  

                   lltGkpPFp..qldlifkkig.............SpeakdLikklLvkdP
                   ++ G+pP+ ++ + + +k+i+++ +++ ++ ++ Sp++k ++++lLv+dP
   mKIAA1142   514 MVDGEPPYFnePPLKAMKMIRdnlpprlknlhkaSPSLKGFLDRLLVRDP 563  

                   ekRlta.eaLedeldikaHPff<-*
                   ++R ta e+L+       HPf+   
   mKIAA1142   564 AQRATAaELLK-------HPFL    578  

TyrKc: domain 1 of 1, from 327 to 578: score 61.5, E = 6.1e-15
                   *->ltlgkkLGeGaFGeVykGtlk...ieVAVKtLkeda...keeFlrEa
                      l    k+GeG  G+V+ +t ++++  VAVK++   +++++e + +E 
   mKIAA1142   327    LDNFIKIGEGSTGIVCIATVRssgKLVAVKKMDLRKqqrRELLFNEV 373  

                   kiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLldyLr
                    iM+ +  +H+N+V ++   + +       + l++vmE+ egG+L d   
   mKIAA1142   374 VIMRDY--RHENVVEMYNSYLVG-------DELWVVMEFLEGGALTDIVT 414  

                   knrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenkvvKI
                    +r   + ++    +l + +  + L+ ++++HRD+    +L++++++vK 
   mKIAA1142   415 HTR--MNEEQIAAVCLAVLQALAVLHAQGVIHRDIKSDSILLTHDGRVKL 462  

                   sDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEslkdgkFt
                   sDFG +  +  +        + r k+  g+       WmAPE +    + 
   mKIAA1142   463 SDFGFCAQVSKE--------VPRRKSLVGTP-----YWMAPELISRLPYG 499  

                   skSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkkGy..Rlpk
                   ++ D+WS GV+  E+  +Ge+PY +      ++  +++ +++  ++Rl+ 
   mKIAA1142   500 PEVDIWSLGVMVIEMV-DGEPPYFN-----EPPLKAMKMIRDNLppRLKN 543  

                   PendlpiSsvtCPdelYdlMlqCWaedPedRPtFsel..verl<-*
                    +         +++ l     +   +dP++R t +el ++ +l   
   mKIAA1142   544 LHK--------ASPSLKGFLDRLLVRDPAQRATAAELlkHPFL    578  

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